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Öğe Simultaneous choriocarcinoma metastases to brain, spine and lung(2007) Güzel A.; Tatli M.; Zileli M.Cerebral metastasis of choriocarcinoma is well documented. However, multifocal metastasis of choriocarcinoma is an extremely rare event. A 20-year-old married woman was admitted through A & E presented with spastic paraplegia and sensory deficit below T4 level. She was not having any obstetric or gynaecological problems. Magnetic resonance imaging revealed bilateral multiple lesions in the lungs and an extradural mass of T2-T3 vertebrae, along with metastatic haemorrhagic cerebral lesions. The patient was operated and histopathology revealed choriocarcinoma. She died on the 5th postoperative day in intensive care unit due to massive haemoptysis. Lung and brain haemorrhages of metastatic choriocarcinoma are indicators of a poor outcome in gestational trophoblastic neoplasia. To our knowledge, this is the first reported case of multifocal choriocarcinoma metastases in brain, thoracic spine and lungs.
