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Öğe The effects of bilateral adrenalectomy on mandibular condyle of rat(Indian Veterinary Journal, 2008) Zengingul, A. I.; Ketani, M. A.; Baskan, S. Z.; Elitok, O. M.This study was aimed to evaluate the scaning electron microscope changes of mandibular condule in adrenalectomised rats.Öğe Effects of Ovariectomy and Bilateral Molar Teetless on Mandibular Condyle of Rat(Medwell Online, 2012) Zengingul, A. I.; Ketani, S.; Karadede, M. I.; Uysal, E.; Ketani, M. A.This study, researchers examined the ovariectomy and bilateral molar teetless of mandibular condyle in rat by histologically and histomorphometrically. In this part of the study, 12 Wistar Albino rats, 120 days old and weighing 200-250 g were used. The rats were divided into three groups, a control and two experimental group. The experimental groups of rats were subjected to ovariectomy in. order to create oestrogen deficiency and bilateral molars extraction. After 35 days of ovariectomy, control and experimental group rats were killed and their mandible condyle removed. The speciemens were stained with Hematoxylin and Eosin (HE) and examined for structure of histologically and histomorphometrically. Histomorphometric analysis; mandibular condyle of control and experimental groups were statistically significant results of the histological layers (p<0.05). It was concluded that ovariectomy application and molar teetless can induce histopathological and histomorphometrically changes in the structure of the condyle.Öğe THE EFFECTS OF SIALOADENECTOMY AND EPIDERMAL GROWTH FACTOR ON GINGIVAL TISSUE IN RATS: AN ULTRASTRUCTURAL STUDY(Diagnosis Press Ltd, 2008) Dag, A.; Ketani, M. A.; Zengingul, A. I.; Ketani, S.Submandibular salivary glands (SMGs) synthesize, accumulate and secrete a large amount of epidermal growth factor (EGF) in rats. EGF stimulates cell proliferation and differentiation by binding to its reseptors (EGFR). The aim of the present study was to mimic an endogenous epidermal growth factor deficiency through sialoadenectomy in paralel to exogenous EGF administration and to observe the ultrastructural changes in rat gingival tissue, employing electron microscopy Thirty adult female Wistar albino rats were divided randomly into three groups: a control group (n:10), a sialoadenectomy group (n:10) and a sialoadenectomy group to which an EGF was administered (n: 10). The experimental groups of rats were subjected to sialoadenectomy in order to create EGF deficiency. After 2 7 days both control and experimental rat groups were euthanized by pentobarbital and their gingival tissue was removed. Tissue samples from gingiva were processed for ultrastructural study Electron microscopic evaluation indicated that while in the control group gingival tissues showed a normal appearance changes were observed in the experimental groups. We observed a partial degeneration of the epithelial cell junctions. Widespread crystolisis was also observed in a group of mitochondria. It is concluded that epidermal growth factor deficiency achieved by sialoadenectomy caused ultrastructural changes in gingival epithelium.Öğe Effects of unilateral molar teeth less condition on the mandibular condyle of rats(Indian Veterinary Journal, 2006) Zengingul, A. I.; Dag, A.; Nigiz, R.; Ketani, S.[Abstract Not Available]Öğe Tooth wears and dentoalveolar compensation of vertical height(Taylor & Francis Ltd, 2007) Zengingul, A. I.; Eskimez, S.; Deger, Y.; Kama, J.The present study aims to determine differences in vertical facial dimensions as a result of dental wear The study consisted of 20 subjects with vertical tooth wear. The mean age of sample was 52.4 years. The control group consisted of 20 dental school students. The mean age of control group was 22 years (subjects with severe malocclusion or tooth wear were not included). All subjects cephalometric and panoramic radiographs were taken from natural head posture. Dentoalveolar height was recorded as in the maxilla and in the mandible on the both cephalometric and panoramic radiograph. Result of the cephalometric measurements showed that significant differences lower face height (ANS-Me), lower dentoalveolar height (Ii-MP) between the groups (p< 0, 001). Upper dentoalveolar height (Is-PP) and total face height (N-Me) was greater than control group (P<0,01). According to the result of panoramic measurement dentoalveolar compensatory, of samples was greater than control group in mandibuler premolar area (p < 0, 05). We found out that dentoalveolar structure is compensating the loss of vertical height when there is the severe occlusal tooth wears.
