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    The effects of age and gender on some biochemical serum parameters in Zom sheep raised in the vicinity of Karacadağ
    (Israel Veterinary Medical Association, 2015) Durak M.H.; Erkan R.E.C.; Çelik R.; Yokuş B.; Kurt D.; Gürgöze S.
    A hundred and seventy three clinically healthy Zom sheep aged 1-6 years and grazed on grassland under similar conditions in six villages of the Karacadağ and Ovabağ towns of the central, Bismil and Çınar districts of Diyarbakır province. The effect of gender in the evaluation for serum glucose, ?~glutamyltransferase, and alkaline phosphatase were observed for Zom sheep. The effect of age on the assessment made by taking into consideration the serum cholesterol, direct bilirubin, very low-density lipoprotein, alkaline phosphatase, ?~glutamyltransferase and direct bilirubin and high-density lipoprotein were also observed. In conclusion the age and gender of the Zom sheep needs to be taken into consideration in order to ensure an accurate clinical diagnosis and prognosis. © 2015, Israel Veterinary Medical Association. All rights reserved.
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    Öğe
    Protective role of lycopene on aflatoxin B1 induced changes sperm characteristics and testicular damages in rats
    (2010) Taş M.; Güney Saruhan B.; Kurt D.; Yokuş B.; Denli M.
    The aim of this study was to investigate if lycopene could diminish the adverse effects of aflatoxin B1 (AFB1) on sperm characteristics, the testes, epididymis and oxidative stress in rats. A total of 28 adult male Wistar-Albino rats (8 weeks old weighing 180-220 g) were divided into four groups; Controls, lycopene treated rats (10 mg/kg BW, daily by gavage), AFB1 treated rats (2.5 mg/kg BW, single dose intra peritonal) and lycopene (10 mg/kg BW, daily by gavage) + AFB1 (2.5 mg/kg BW, single dose intra peritonal) treated rats. Traits of reproductive organs (testes and sperm characteristics, testicular histological findings and the testicular tissue oxidative status) were determined after 15 days of treatment. The sperm motility was significantly decreased while the rate of total abnormal sperms was significantly increased in rats treated with AFB1 alone compared to their levels in controls (P<0.001). The level of testes malondialdehyde (MDA) in rats treated with AFB1 was significantly higher than its level in controls (P<0.001). Treatment with AFB1 significantly decreased testes diameter and seminifer epithelium thickness (P<0.0001) when compared with the others. Similarly, the thickness of the germinative cell layer at seminifer tubul (ST) in rats treated with AFB1 was significantly smaller than controls. Treatment with lycopene significantly increased sperm motility (P<0.001) and alleviated the many negative effects of AFB1 on sperm characteristic and testicular damage in rats. In conclusion our results showed that consumption of 10 mg of lycopene/ BW given by gavage protected the rats to the toxicity of AFB1 when it is administrated as a single dose intraperitoneally.