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Öğe Chronic fatigue and depression experienced by senior students of dicle university(Acta Medica Mediterranea, 2014) Aslan I.; Tanriverdi M.H.; Erten Bucaktepe P.G.; Celepkolu T.; Yilmaz A.Aims: Chronic fatigue syndrome (CFS) is a debilitating disease that presents with a chronic fluctuating course of multi-systemic symptoms. The purpose of this study was to examine chronic fatigue syndrome and depression, experienced by senior students attending Diyarbaki{dotless}r Dicle University, to investigate the factors involved in the development of CFS and depression and to shed light on preventive measures that can be taken to overcome CFS, with the help of the collected data. Methods: The study was conducted in Dicle University Campus between January and April 2012 and 525 students participated in the study. The questionnaire, used for this study, included 22 questions regarding the participants' demographic features, working conditions, habits and activities and a 17-item extracted from the HAM-D scale (Hamilton Depression Rating Scale), and the CFS evaluation criterias of the CDC (Center for Disease Control and Prevention). In order to analyze the data, Student's t-test, Chi-square (Fisher's exact) test, One way Analysis of Variance (ANOVA), Pearson correlation test and logistic regression analysis were used. Results: Of all the students, 2% of them (n=11) were found to suffer from CFS. CFS was found to be more prevalent among females. Minor depressive symptoms were found to occur in 92 students (18%), and 20 students (4%) had major depressive symptoms. Gender, non-relaxing sleep, social life and person's perception of their health status were found to have a relationship with CFS. The CFS cases were found to have a higher HAM-D scale value. Conclusion: The school stress experienced by the students and their social life experiences are influential on depression and on the development of CFS. For this reason, the guidance departments and social support units of universities must be improved, in order to prevent CFS.Öğe The effect of magnesium carbonate on NMR spin-lattice relaxation rate in iron-doped solution of serum(1991) Yilmaz A.; Ensari Y.; Ebeoglu M.A.; Rici C.; Vidimari R.; Renzi R.[No abstract available]Öğe The plasma level of parathormon and homocysteine in migraine patients; Another aspect on migraine-stroke associaton(Acta Medica Mediterranea, 2015) Varol S.; Akil E.; Yunce M.; Kaplan B.; Özdemir H.H.; Arslan D.; Yilmaz A.The pathogenesis of migraine has been well studied and it is associated with oxidative stress, neurogenic inflammation, and endothelial dysfunction. To the best of our knowledge, no studies have focused on the impact of the parathormone (PTH) and homocysteine levels in migrane patients. To determine migraine-stroke association, our study focused on the levels of PTH and homocysteine in the blood of migraine patients. Fifty five migraine patients in the presence or absence of aura were included. The patients in the migraine group were divided into subgroups: (I) migraine in the attack period (with and without aura) (n = 23), and (II) migraine in the interictal period (with and without aura) (n = 32). As a control, 30 healthy volunteers were also enrolled in the study. As a result, we found that PTH and homocysteine levels of the migraine patients were increased significantly when compared with healthy volunteers (p = 0.001). The PTH and homocysteine levels of the patients with aura were higher than patients without aura in the migraine group (p < 0.05). There were no statistically significant differences between PTH/homocysteine levels and migraine duration or migraine attack frequency (p > 0.05). There was a positive correlation between PTH and homocysteine levels in the migraine patients (p = 0.001, r = 0.49). To summarize, we found statistically significant increases in PTH and homocysteine blood levels of migraine patients versus healthy volunteers. These results may help to understand the pathogenesis of migraine ischemia, and potentially identify new prognostic markers for this condition.Öğe The value of new inflammatory parameters in Malignant mesothelioma prognosis(Acta Medica Mediterranea, 2015) Tanrikulu A.C.; Hocanli I.; Yilmaz A.; Meteroglu F.; Taylan M.; Demir M.; Kaya H.Aim: Malignant mesothelioma (MM) has a poor prognosis. Inflammation is associated with MM prognosis and symptoms. Several inflammatory markers were investigated to estimate MM prognosis. We investigated the role of available inflammatory index and markers for MM prognosis. We developed the advanced mesothelioma index (AMI) to assess the degree of inflammation in MM. Materials and methods: We performed a retrospective study of 202 MM patients (116, male, 86 female) evaluated at Dicle University. Demographic parameters and laboratory data were collected. The AMI was calculated as Body Mass Index*serum albumin value (g/dl)/platelet-to-lymphocyte ratio. Results: The mean age of patients was 59.04 years. A total of 135 (66.8%) patients showed epithelial-type histopathological subtypes and 177 patients had pleural MM. The mean survival time was 13.1±11.5 months in the all MM patients. Twenty-four potential prognostic factors were associated with a poor outcome and then analyzed in the univariate analysis. Eighteen of them were definitely associated with a poor prognosis. These 18 potential prognostic factors were analyzed in the multivariate analysis. Based on the results of the multivariate analysis, only patients with an AMI<0.5 had an associated poor prognosis. An AMI<0.5 increased the mortality rate by 10.47. Furthermore, low AMI was associated with other bad inflammatory markers (such as high platelet count, high C reactive protein level, low Body Mass Index, low albumin and low hemoglobin). Conclusion: Our findings indicate that the AMI can be used to assess the degree of systemic inflammation.
