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Öğe Assessment of Serum S100 Protein Levels in Patients with Fibromyalgia(Clinical & Exper Rheumatology, 2014) Cavas, Husamettin; Oktayoglu, Pelin; Verim, Sabahattin; Em, Serda; Caglayan, Mehmet; Bozkurt, Mehtap; Yildiz, Ismail[Abstract Not Available]Öğe Comparison of left ventricular functional parameters obtained from three different commercial automated software cardiac quantification program packages and their intraobserver reproducibility(Springer, 2011) Dostbil, Zeki; Ariturk, Zuhal; Cil, Habib; Elbey, Mehmet Ali; Tekbas, Ebru; Yazici, Mehmet; Yildiz, IsmailObjective ECG-gated myocardial perfusion scintigraphy (MPS) can be used to determine several cardiac functional parameters (e. g., left ventricular ejection fraction (LVEF), end-diastolic volume (EDV), and end-systolic volume (ESV)). In this study, we aimed to compare these cardiac functional parameters calculated by the following cardiac quantification programs: Emory Cardiac Toolbox (ECTb), Quantitative Gated SPECT (QGS), and Myometrix. We also evaluated reproducibility of the cardiac programs. Methods Fifty-seven patients (27 male, 30 female) at Elazig Research and Training Hospital from 2008 to 2009 were included in this study. In all patients, (99m)Tc-MIBI ECG-Gated (8-bin frame mode) myocardial perfusion scintigraphies were performed. By using 3 different cardiac quantification programs (ECTb, QGS, and Myometrix); LVEF, EDV, and ESV were calculated. The same raw data of MPS images were reprocessed at different time periods, and these 3 parameters were recalculated. LVEF, EDV, and ESV yielded by 3 different programs were compared for interprogram variability assessment, and parameters calculated at two different time periods were compared to evaluate intraprogram reproducibility. Results There were statistically significant differences between ECTb, QGS, and Myometrix programs for LVEF, EDV, and ESV (p < 0.001). There was also a statistically significant correlation between LVEF and EDV (p < 0.001, r = 0.546; p < 0.001, r = 0.45, respectively), but no statistically significant correlation was present between the ESV values (p > 0.05, r = 0.09). Statistically significant differences were not found between the values of LVEF, EDV, and ESV obtained from the first and second reconstruction analysis of 3 cardiac quantification programs. Discussion Different MPS cardiac software programs give variable (but correlated) LVEF and left ventricular volumetric measures. Those obtained from different cardiac softwares cannot be used interchangeably. Our findings have shown that ECTb, QGS, and Myometrix programs are reproducible, with respect to LVEF, EDV, and ESV.Öğe Comparison of the effect of local microvibration and pulsed electromagnetic field application on bone fracture(Wiley-Blackwell, 2015) Bilgin, Hakki Murat; Celik, Ferhat; Akpolat, Veysi; Yildiz, Ismail; Ekinci, Aysun; Gem, Mehmet[Abstract Not Available]Öğe Determination of dermatology life quality index, and serum C-reactive protein and plasma interleukin-6 levels in patients with chronic urticaria(Termedia Publishing House Ltd, 2013) Ucmak, Derya; Akkurt, Meltem; Toprak, Gulten; Yesilova, Yavuz; Turan, Enver; Yildiz, IsmailIntroduction: C-reactive protein (CRP) and interleukin-6 (IL-6), which is one of its most important simulators, were determined in great amounts in the sera of patients with chronic urticaria (CU). Aim: To determine the levels of IL-6 in patients with urticaria, and evaluate its relationship with urticaria activity scores and Dermatology Life Quality Index (DLQI). Material and methods: Fifty-three patients with CU were included in the study successively by determining their urticaria activity scores (0-3) and DLQI (0-5). The CRP and IL-6 were measured by immune assay methods. Thirty-two healthy subjects were included as a control group. Results: Serum levels of IL-6 and CRP were significantly higher in patients with CU compared to healthy controls (p < 0.001, p = 0.026 respectively). There was a statistically significant correlation among urticaria activity scores and IL-6 and CRP concentration (p = 0.004, p = 0.042). This correlation was more significant in patients who had moderate and severe disease activity scores than in those who had mild disease activity score (p < 0.001, p < 0.001, respectively). There was a statistically significant association between DLQI and IL-6 (p = 0.025). This correlation was very significant in patients who had severe and very severe disease activity scores (p < 0.001, p < 0.001, respectively). DLQI scores and serum levels of IL-6 were significantly different in the very severe group compared to healthy controls (p = 0.024). Conclusions: The levels of CRP and IL-6 are increased in patients with CU. A relationship of DLQI and urticaria activity scores with CRP and IL-6 was found. These findings support the relationship between the inflammatory process in CU and the clinical findings.Öğe Effects of Nicotine on Rat Tongue Muc Histopathological and Immunohistochemical Analysis(Sci Printers & Publ Inc, 2016) Eratilla, Veysel; Uysal, Ibrahim; Deveci, Engin; Gunes, Rojdan Ferman; Eratilla, Elif; Yildiz, Ismail; Soker, SevdaOBJECTIVE: To evaluate the histopathological and immunohistochemical effects of systemically administered nicotine on rat tongue mucosa. STUDY DESIGN: Rats were assigned to groups: the experimental group received nicotine ically (nicotine sulphate 2 mg/kg subcutaneously for 28 days), while the rats in the trol grow ere administered physiological saline mL subcutaneously for 28 days). All animals sacrificed at the end of the study, and tongue tissue ere removed and prepared according his histological procedures. Sections were sta toxylin a sin and observed by. Immunorec y of tongue mucosa , 'E-ca Ilagen IV, and VEr by immunhistochemical staining. RESULTS: There w if cant differences in the average histlogical a between the nicotine-treated treated gr Morphological changes, including inflammatory I to infiltration and cellular desquamation, blood dilation, hemorrhage, and epithelial degeneration r. re noted. Further, E-cadherin expression w significantly decreased in the nicotine-treated grow,w the untreated group. The nicotine treat up showed an increase in collagen IV secondary ae and basal cells. CONCLUSION: The increased level of VEGF exprescs n in the nicotine-treated group may have affected endothelial cell apoptosis.Öğe Emotional and Behavioral Impacts of the February 6, 2023 Earthquake on Children with Autism Spectrum Disorder: An Evaluation from the Parental Perspective(Springer/Plenum Publishers, 2024) Simsek, Biradost Boran; Keskin, Gulseren; Yildiz, Ismail; Eksi, AliPurposeEarthquakes have serious psychosocial and emotional effects on children diagnosed with autism spectrum disorder (ASD) and their parents. The limited number of studies investigating the earthquake experience of children with ASD and their parents indicates a need to improve existing research in this area. The aim of this study was to assess parents' experiences with their children after the earthquake and their reactions to the earthquake.MethodsThis study was subjected to analysis via both phenomenological and thematic analysis methods on the basis of the results of semistructured interviews with the parents of 21 children with ASD who were receiving their education in special education and rehabilitation centers.ResultsTwo principal themes were discerned: the first theme, entitled Post-Eartquake Responses in Children and the second, entitled Parents' Earthquake Experiences and Coping Strategies, were identified. Earthquakes had a significant effect on children's bodily, behavioural and emotional responses. In addition, parents were compelled to devise a range of coping strategies to manage their emotional responses to the earthquake and to facilitate their children's access to constrained educational opportunities and adapt to evolving social dynamics.ConclusionIn disaster situations, access to multidisciplinary support programs for children diagnosed with ASD and their families is highly important. These programs, designed through collaboration across various fields of expertise, can offer comprehensive solutions to the emotional, social, and physical challenges faced by children and their families.Öğe Evaluation of postoperative undescended testicles using point shear wave elastography in children(Elsevier Science Bv, 2016) Hattapoglu, Salih; Goya, Cemil; Arslan, Serkan; Alan, Bircan; Ekici, Faysal; Tekbas, Guven; Yildiz, IsmailPurpose: To demonstrate the difference in tissue stiffness by comparing the value of the shear wave velocity (SWV) of postoperative undescended testicles with that of normal testes. Methods: This study included 39 patients and 30 healthy controls. US and p-SWE (VTQ) were performed using with a linear probe (4-9 MHz). Forty-seven operated undescended testicles comprised Group A, 27 testes with normal scrotal placement since birth in patient population comprised Group B. A total of 60 testes in 30 healthy controls were included as Group C. Finally, the testes of Group A, B, C were statistically compared in terms of the SWV and volume. Results: The shear wave values of the 47 testes in Group A were 0.75-2.8 (median, 1.1) m/s, and the SWVs of the 27 testes in Group B were 0.62-1.2 (median, 0.84) m/s. The SWVs of the 60 testes in Group C were 0.65-1 (median, 0.82) m/s. The testicular volumes of Group A ranged from 0.19 to 4.7 (median, 0.15) cm(3), Group B ranged from 0.34 to 8 (median, 0.74) cm(3) and Group C ranged as 0.4-15.5 (median, 0.91) cm(3). Conclusions: VTQ method of p-SWE is a new method that may reveal the difference in stiffness between scrotally placed testes and postoperative undescended testicles. (C) 2016 Elsevier B.V. All rights reserved.Öğe The frequency of workplace violence against healthcare workers and affecting factors(Public Library Science, 2023) Sari, Hidir; Yildiz, Ismail; Baloglu, Senem cagla; oezel, Mehmet; Tekalp, RonayBackgroundWorkplace violence has become a global issue, especially among healthcare workers. This study aimed to determine the influencing factors and legal processes of workplace violence incidents, as well as the frequency of workplace violence in a tertiary hospital. MethodsThis observational, descriptive, retrospective frequency study was conducted between January 2020 and March 2022. This study examined the workplace violence records of 135 healthcare professionals at a tertiary hospital's Patient Rights and Employee Safety and Law departments. Factors affecting workplace violence were categorized as noncompliance with the procedure, communication, and dissatisfaction. ResultsWorkplace violence frequency was observed in the cumulative total of 10821 healthcare workers at 1.2%. In terms of workplace violence types, 71.9% were verbal and 28.1% were physical. In terms of exposure to workplace violence, doctors accounted for 62.3%, nurses for 20%, and medical secretaries for 7.4%. Most cases were observed in outpatient clinics (34.8%), followed by emergency departments (25.9%). Among the main reasons for workplace violence against healthcare workers, non-compliance with procedures (49.6%), communication (27.4%), and dissatisfaction (23.1%) were identified. Legal aid was provided to all notifications of workplace violence. 37.1% were not prosecuted, 55.5% were under investigation, 4.4% were accepted indictments, and 3.0% were punished by a judicial fine. ConclusionThis study can provide significant contributions to the formulation of workplace violence prevention policies and programs by analyzing white-code notifications for workplace violence frequency and preventable factors. Healthcare workers may have underreported workplace violence events due to the length of the proceedings and the perceived lack of protection from legal regulations.Öğe HIGH OCCURRENCE OF METABOLIC SYNDROME IN PATIENTS WITH RHEUMATOID ARTHRITIS(Oxford Univ Press, 2011) Karakoc, Mehmet; Batmaz, Ibrahim; Tahtasiz, Mehmet; Nas, Kemal; Cevik, Remzi; Tekbas, Ebru; Yildiz, Ismail[Abstract Not Available]Öğe HLA-DRB1 Alleles Distribution in Patients With Rheumatoid Arthritis in A Tertiary Center in the Southeastern Anatolia Region of Turkey(Galenos Yayincilik, 2013) Batmaz, Ibrahim; Sariyildiz, Mustafa Akif; Dilek, Banu; Yildiz, Ismail; Nas, Kemal; Ayyildiz, Orhan; Cevik, RemziObjective: The HLA-DRB1 alleles play an important role in the genetic predisposition to rheumatoid arthritis (RA). The relationship between HLA-DRB1 and rheumatoid arthritis show differences according to various ethnic groups and geographical distributions. The aim of this study was to determine the distribution of HLA-DRB1 among the Turkish RA patient population in the Southeastern Anatolia Region. Materials and Methods: 96 patients diagnosed with RA and a control group consisting of 84 healthy individuals were enrolled in the study. The HLA-DRB1 type and subtypes were specified using the polymerase chain reaction with sequence specific primers (PCR-SSP) method. The between-group HLA-DRB1 type and certain subtype frequencies were compared. Results: The DRB1*10 alleles were found to be statistically significantly higher in patients with RA compared to the control group (p=0.001). However, the DRB1*07 and DRB1*11 alleles were statistically significantly lower in patients with RA (p<0.001 and p=0.02, respectively). In the RA patient group, the DRB1*0401, DRB1*0408 and DRB1*1001 subtypes were found to be statistically significantly higher (p=0.04, p=0.01, p=0.005, respectively), while the DRB1*0402, DRB1*0403 and DRB1*0701 subtypes were statistically significantly lower (p=0.01, p=0.02, p<0.001, respectively). Conclusion: This study has revealed the HLA-DRB1 distribution in the Southeastern Anatolia Region of Turkey. DRB1*10 type and DRB1*0401, DRB1*0408, DRB1*1001 subtypes were observed to be related with RA. DRB1*07, BRB1*11 types and DRB1 *0402, DRB1*0403, DRB1*0701 subtypes were accepted as protective alleles and subtypes.Öğe HLA-DRB1 EXPRESSION IN THE RHEUMATOID ARTHRITIS PATIENTS AMONG THE POPULATION IN THE SOUTHEAST ANATOLIAN REGION OF TURKEY(Oxford Univ Press, 2012) Batmaz, Ibrahim; Sariyildiz, MehmetAkif; Dilek, Banu; Yildiz, Ismail; Ayyildiz, Orhan; Nas, Kemal; Cevik, Remzi[Abstract Not Available]Öğe Investigation of the effects of pulsed electromagnetic fields and calcium-channel blockers on osteogenesis(Wiley-Blackwell, 2016) Bilgin, Hakki Murat; Agacayak, Serkan; Akpolat, Veysi; Yildiz, Ismail[Abstract Not Available]Öğe Possible Association of FAS and FASLG Polymorphisms with the Risk of Idiopathic Azoospermia in Southeast Turkey(Mary Ann Liebert, Inc, 2014) Balkan, Mahmut; Atar, Murat; Erdal, Mehmet Emin; Rustemoglu, Aydin; Yildiz, Ismail; Gunesacar, Ramazan; Hatipoglu, Namik KemalTo investigate the association of the genetic variants of FAS/FASLG cell death pathway genes in male infertility, we genotyped the FAS -670A/G, -1377G/A, and FASLG -124A/G single-nucleotide polymorphisms (SNPs) by real-time polymerase chain reaction in 108 infertile men with idiopathic azoospermia and in 125 proven fertile controls. The distribution of genotypes and alleles for SNPs at FAS -1377G/A and FASLG -124A/G loci were determined not to be statistically different between the case and control groups. However, the genotype frequencies of SNPs, FAS -670AA and FAS -670AG, were found to be significantly different between the case and control groups. Whereas the FAS -670AA genotype might be regarded as a higher predisposition for idiopathic azoospermia, FAS -670AG could be interpreted to mean that this genotype provides protection against idiopathic azoospermia. The study of combined genotype and haplotype frequencies has found statistically significant differences between case and control subjects for some combinations. The AA-GG binary genotype for the FAS670 and FAS1377 loci couple, in particular, may have a high degree of predisposition to idiopathic azoospermia. Our results suggest that FAS -670A/G SNP may be a genetic predisposing factor of idiopathic azoospermia among southeastern Anatolian men. Larger studies are needed to verify these findings. Furthermore, our data indicated a possible linkage between the FAS and FASLG genes and idiopathic azoospermia.Öğe Prolidase, Matrix Metalloproteinases 1 and 13 Activity, Oxidative-Antioxidative Status as a Marker of Preterm Premature Rupture of Membranes and Chorioamnionitis in Maternal Vaginal Washing Fluids(Ivyspring Int Publ, 2013) Soydinc, Hatice Ender; Sak, Muhammet Erdal; Evliyaoglu, Osman; Evsen, Mehmet Siddik; Turgut, Abdulkadir; Ozler, Ali; Yildiz, IsmailObjective: Etiology of premature preterm rupture of membranes (PPROM) is not yet completely known and chorioamnionitis is one of the most important complications of its. We aimed to evaluate whether prolidase, matrix metalloproteinases, oxidative-antioxidative status, and inflammation markers in vaginal washing fluid (VWF) were associated with etiology of PPROM and whether these markers could be used to predict chorioamnionitis in PPROM. Study Design: This prospective case control study enrolled fifty pregnant women with PPROM and 50 healthy pregnant women. The VWF samples were taken at the time of admission in the PPROM group and patients were followed for chorioamnionitis. Prolidase, matrix metalloproteinases, oxidative-antioxidative status, and inflammation markers in VWF were assayed. Results: VWF levels of prolidase, matrix metalloproteinases 1-13 (p<0.001), oxidative stress parameters, total oxidative stress (TOS) (p < 0.001) and oxidative stress index (OSI) (p = 0.002), and hs-CRP (p = 0.045) were significantly higher in the PPROM group than in the controls. Antioxidative status parameters, levels of paroxanase (PON-1) (p < 0.001) and total antioxidant capacity (TAC) (p < 0.001), were significantly lower in the PPROM group than in the controls. Mean VWF levels of prolidase (p < 0.001), metalloproteinases (p<0.05), and oxidative-antioxidative status parameters (p<0.05) were significantly different in women with versus women without chorioamnionitis in the PPROM group. Prolidase, MMP-13, TOS, TAC, and PON-1 were found as important predictors for chorioamnionitis in the PPROM group by the multivariate logistic regression analysis. When the ROC curve analysis for prolidase, MMP-13, TOS, TAC, and PON-1 were performed, all of them were statistically significant for area under the curve (areas under the curve were 0.94, 0.90, 0.80, 0.25, and 0.19, respectively). Conclusions: This study showed that collagen turnover mediators, especially prolidase, and increased oxidative stress are significantly associated with PPROM. Also, chorioamnionitis can be predicted with prolidase, MMP-13, TOS, TAC, and PON-1 in PPROM patients.Öğe The ratio of HBsAg and AntiHCV Seropozitivity in pregnant and other patients admitted to Department of Obstetrics and Gynecology and their relationships with the other risk factors(Duzce Univ, 2012) Yildiz, Bahri; Bucaktepe, P. Gamze Erten; Yildiz, Ismail; Kara, Ismail HamdiObjective: In this study, it has been aimed to define and compare sociodemographic properties of patients with positive HBsAg and AntiHCV who had hospitalized between January and December 2010 at Department of Obstetrics and Gynecology, Dicle University Faculty of Medicine (DUFM). Method: In this retrospective and descriptive study, HBsAg and/or AntiHCV positive 132 patients were detected among a total of 4491 scanned patients by using chemiluminescent microparticle immunoassay (CMIA) method. Admission diagnoses, ages, sociodemographic characteristics, obstetric histories, biochemical values, babies' conditions-if they are pregnant, lengths of hospital stay and risk factors for hepatitis of these patients were identified. AntiHCV and HBsAg-positive patients were compared according to their properties listed above. Results: 46.2% of studied patients (n=61) were between the ages of 26-35 years, 67.4% (n=89) of them were admitted from rural areas and 62.9% of them had green card (n=83). Fourty six of the patients (34.9%) were admitted due to problems relating to the pregnancy complications or baby. HBsAg and AntiHCV positivity rates were determined to be 2.63% (n=118) and 0.29% (n=13), respectively. Among the pregnant women admitted to the clinic, HBsAg and AntiHCV positivity rates were determined to be 2.66% and 0.20%, respectively. Conclusion: Since taking infection at birth will increase the risk of developing a fatal complication in advancing ages, all pregnant women should be examined against preventable disease HBV. This should be done as routine antepartum examination. Carrier mothers should be enlightened on the importance of passive and active immunization after delivery of the baby.Öğe The Relationship between Disease Activity and Visceral Fat in Patients with Rheumatoid Arthritis(Clinical & Exper Rheumatology, 2014) Aydin, Fatma; Caglayan, Mehmet; Bozkurt, Mehtap; Oktayoglu, Pelin; Em, Serda; Yildiz, Ismail; Nas, Kemal[Abstract Not Available]Öğe Relationship between serum leptin level and disease activity in patients with systemic sclerosis(Springer London Ltd, 2014) Budulgan, Mahmut; Dilek, Banu; Dag, Sevin Buluttekin; Batmaz, Ibrahim; Yildiz, Ismail; Sariyildiz, Mustafa Akif; Cevik, RemziTo determine the relationship between serum leptin levels and disease activity in systemic sclerosis (SSc). A total of 60 subjects (30 controls and 30 patients) were included. The inflammatory markers and leptin levels were evaluated and body mass index (BMI) was measured for both groups. The assessment of the skin involvement was performed based on the modified Rodnan skin score (mRSS). Disease activity was evaluated according to the Valentini scleroderma disease activity index. There was a significant difference between the patient and control groups in terms of BMI (p < 0.05); however there was no difference with regards to age and gender (p > 0.05). Valentini scores and mRSS were determined to be significantly higher in active patients (n = 14) than in inactive patients (n = 16) (p < 0.05). No significant difference was determined between groups in terms of leptin levels (p > 0.05). However, leptin levels were significantly lower in active patients than in inactive patients (p < 0.05). We found a significant positive correlation between serum leptin and BMI (p < 0.05), and leptin and serum C3 levels (p < 0.05); no relationship was detected between leptin and other parameters. Leptin can be used as an activity marker in SSc. Further studies, including larger series, should be carried out to clarify this relationship.Öğe Relationship of the HLA-DRB1 alleles and seropositivity, anti-MCV, functional status and radiological damage in Turkish patients with rheumatoid arthritis(Ios Press, 2013) Sariyildiz, Mustafa Akif; Batmaz, Ibrahim; Cetincakmak, Mehmet Guli; Yildiz, Ismail; Nas, Kemal; Cevik, RemziOBJECTIVES: The HLA-DRB1 gene plays an important role in the genetic predisposition to rheumatoid arthritis. The anti-citrullinated protein antibody (ACPA) is known to be associated with the susceptibility to rheumatoid arthritis (RA), as well as the severity of the disease. The aim of this study is to determine the HLA genes that are associated with the severity of the RA measured by seropositivity, functional status, radiological damage and the anti-modified citrullinated vimentin (MCV) levels. MATERIAL AND METHOD: Ninety-six patients diagnosed with rheumatoid arthritis and a control group consisting of 84 healthy individuals were enrolled in the study. The HLA-DRB1 type and subtypes were specified using the polymerase chain reaction with sequence-specific primers (PCR-SSP). The association of the HLA-DRB1 type and subtypes with seropositivity, anti-MCV levels, functional status and anatomical joint damage were explored using the modified Larsen scoring method. RESULTS: The DRB1*01, DRB1*04, DRB1*07, DRB1*10, DRB1*11 and DRB1*15 alleles were found to be related with higher anti-MCV levels (p < 0.05). The DRB1*11 type and the DRB1*1001 subtype were observed to be associated with poor functional status (Stages 3-4). The DRB1*0801 subtype was associated with lower anti MCV levels (OR = 8.35, p = 0.02). DRB1*04 type and DRB1*0405 subtypes were related with radiological damage (OR = 0.52 and 0.25; p = 0.04 and 0.03, respectively). No significant relationship was observed between the RF seropositivity and the HLA-DRB1 alleles. CONCLUSION: This study revealed the association between the HLA alleles and seropositivity, functional status, anti-MCV levels and radiological damage in patients in the Southeast Anatolian region of Turkey.Öğe Which Mechanism is Effective on the Hyperamylasaemia After Coronary Artery Bypass Surgery?(Elsevier Science Inc, 2017) Algin, Halil Ibrahim; Parlar, Ali Ihsan; Yildiz, Ismail; Altun, Zekiye Sultan; Islekel, Gul Huray; Uyar, Ibrahim; Tulukoglu, EnginBackground and Aim Acute pancreatitis is one of the less frequently diagnosed lethal abdominal complications of cardiac surgery. The incidence of early postoperative period hyperamylasaemia was reported to be 30-70% of patients who underwent coronary artery bypass grafting (CABG) with cardiopulmonary bypass (CPB). The mechanism of pancreatic enzyme elevation after cardiac surgery is not clear. Our aim was to determine the relationship between ischaemia associated temporary renal dysfunction and elevation of pancreatic enzymes after CABG. Methods Forty-one consecutive patients undergoing CABG under CPB were prospectively studied to determine serum total amylase, phospholipase A2, macroamylase, Cystatin C and urine NAG levels. Results Hyperamylasaemia was observed in 88% of the cases, with a distribution of 6% at the beginning of cardioplegic arrest, 5% at the 20th minute after cardioplegic arrest, 7% at the 40th minute after cardioplegic arrest, 14% when the heart was re-started, 26% at the 6th hour of intensive care and 30% at the 24th hour of intensive care. All of these patients had asymptomatic isolated hyperamylasaemia, and none of them presented with clinical pancreatitis. As indicators of renal damage; Cystatin C and NAG levels were higher compared to baseline values. Conclusion Amylase began to rise during initial extracorporeal circulation and reached a maximum level postoperatively at 6 and 24 hours. Decreased amylase excretion is the main reason for post CABG hyperamylasaemia.
