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    Pregnancy and H1N1 infection in Southeast Turkey
    (J Infection Developing Countries, 2012) Soydinc, Hatice Ender; Celen, Mustafa Kemal; Yildiz, Bahri; Sak, Muhammet Erdal; Evsen, Mehmet Siddik; Gul, Talip
    Introduction: H1N1 Influenza made a great impact a worldwide, as well as in Turkey, in 2009. Clinical experiences have shown that it had a more serious prognosis in pregnant women. In this report, we summarize the cases of 16 pregnant women with H1N1 Influenza. Methodology: The study included 16 pregnant women hospitalized in Dicle University Hospital with complaints of fever, sore throat, cough and myalgia between October and December 2009. The diagnosis of pandemic H1N1 Influenza was confirmed on nasopharyngeal specimens using real-time reverse-transcriptase polymerase chain reaction (RT-PCR) in all patients. Patients who had the same complaints but were not diagnosed as H1N1 Influenza were excluded. The epidemiological, clinical, diagnostic, and outcome features of the patients were recorded. Results: The median age of the patients was 27 years (range 18-41 years). The mean gestational age was 25.4 weeks (range 5-38 weeks). Two cases were twin pregnancy. Two cases had co-morbid diseases including asthma and anemia. The most frequent admission symptoms were fever in 13 cases (81%), cough in 12 cases (75%) and dyspnea in 6 cases (37,5%). Antiviral treatment (oseltamivir 75 mg p.o. bid) was applied in 15 cases. Four cases needed intensive care monitoring and two of them died (12.5%) because of severe respiratory insufficiency. Conclusion: Patients with late gestational age, the presence of co-morbid disease, and multiple pregnancy have poor prognosis. Immediate intervention with antiviral treatment is associated with reduced severity of the disease and duration of hospital stay.
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    The ratio of HBsAg and AntiHCV Seropozitivity in pregnant and other patients admitted to Department of Obstetrics and Gynecology and their relationships with the other risk factors
    (Duzce Univ, 2012) Yildiz, Bahri; Bucaktepe, P. Gamze Erten; Yildiz, Ismail; Kara, Ismail Hamdi
    Objective: In this study, it has been aimed to define and compare sociodemographic properties of patients with positive HBsAg and AntiHCV who had hospitalized between January and December 2010 at Department of Obstetrics and Gynecology, Dicle University Faculty of Medicine (DUFM). Method: In this retrospective and descriptive study, HBsAg and/or AntiHCV positive 132 patients were detected among a total of 4491 scanned patients by using chemiluminescent microparticle immunoassay (CMIA) method. Admission diagnoses, ages, sociodemographic characteristics, obstetric histories, biochemical values, babies' conditions-if they are pregnant, lengths of hospital stay and risk factors for hepatitis of these patients were identified. AntiHCV and HBsAg-positive patients were compared according to their properties listed above. Results: 46.2% of studied patients (n=61) were between the ages of 26-35 years, 67.4% (n=89) of them were admitted from rural areas and 62.9% of them had green card (n=83). Fourty six of the patients (34.9%) were admitted due to problems relating to the pregnancy complications or baby. HBsAg and AntiHCV positivity rates were determined to be 2.63% (n=118) and 0.29% (n=13), respectively. Among the pregnant women admitted to the clinic, HBsAg and AntiHCV positivity rates were determined to be 2.66% and 0.20%, respectively. Conclusion: Since taking infection at birth will increase the risk of developing a fatal complication in advancing ages, all pregnant women should be examined against preventable disease HBV. This should be done as routine antepartum examination. Carrier mothers should be enlightened on the importance of passive and active immunization after delivery of the baby.