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Öğe Bilateral symptomatic petrous apex effusion(Springer, 2010) Yildirim, Muzeyyen; Senturk, Senem; Guzel, Ebru; Guzel, Aslan; Topcu, IsmailPetrous apex effusions can present with aural fullness, hearing loss and dizziness. Although they can be followed-up when asymptomatic, clinical management of symptomatic patients is controversial. In this study, we present clinical and radiological findings of a 24-year-old patient with bilateral petrous apex effusion. She had been complaining of bilateral aural fullness and dizziness for 2 years. Radiological examinations revealed bilateral petrous apex effusion. After medical treatment, her symptoms gradually disappeared. In all previous published studies, unilateral petrous apex effusions were reported. To our best knowledge, this is the first patient with trapped fluid in bilateral petrous apex.Öğe Congenital os vomer agenesis: Case report and literature review(Vendome Group Llc, 2012) Yorgancilar, Ediz; Yildirim, Muzeyyen; Gun, Ramazan; Meric, Faruk; Topcu, IsmailDefects of the nasal septum occur as a result of a variety of causes, including tuberculosis, irritation, neoplasia, trauma, infection, and chronic inflammatory diseases. Congenital os vomer agenesis as a cause is very rare. We report the case of a 28-year-old man with a defect in the posteroinferior part of the nasal septum that was discovered incidentally during a routine endoscopic examination. The patient was diagnosed with congenital os vomer agenesis, and the diagnosis was confirmed by computed tomography We discuss the features of this case and review the literature on this rare anomaly.Öğe Deep neck space infections: a retrospective review of 173 cases(W B Saunders Co-Elsevier Inc, 2012) Bakir, Salih; Tanriverdi, M. Halis; Gun, Ramazan; Yorgancilar, A. Ediz; Yildirim, Muzeyyen; Tekbas, Guven; Palanci, YilmazPurpose: The purpose of this study is to review our recent experience with deep neck infections and emphasize the importance of radiologic evaluation and appropriate treatment selection in those patients. Materials and Methods: The records of 173 patients treated for deep neck infection at the Department of Otolaryngology and Head and Neck Surgery of Dicle University Hospital during the period from 2003 to 2010 were retrospectively reviewed. Their demography, symptoms, etiology, seasonal distribution, bacteriology, radiology, site of deep neck infection, durations of the hospital admission and hospital stay, treatment, complications, and outcomes were evaluated. The findings were compared to those in the available literature. Results: Dental infection was the most common cause of deep neck infection (48.6%). Peritonsillar infections (19.7%) and tuberculosis (6.9%) were the other most common cause. Pain, odynophagia, dysphagia, and fever were the most common presenting symptoms. Radiologic evaluation was performed on almost all of the patients (98.3%) to identify the location, extent, and character (cellulitis or abscesses) of the infections. Computed tomography was performed in 85.3% of patients. The most common involved site was the submandibular space (26.1%). In 29.5% of cases, the infection involved more than one space. All the patients were taken to intravenous antibiotic therapy. Surgical intervention was required in 95 patients (59.5%), whereas 78 patients (40.5%) were treated with intravenous antibiotic therapy alone. Life-threatening complications were developed in 13.8% of cases; 170 patients (98.3%) were discharged in stable condition. Conclusion: Despite the wide use of antibiotics, deep neck space infections are commonly seen. Today, complications of deep neck infections are often life threatening. Although surgical drainage remains the main method of treating deep neck abscesses, conservative medical treatment are effective in selective cases. (C) 2012 Elsevier Inc. All rights reserved.Öğe Effects of chlorhexidine/benzydamine mouth spray on pain and quality of life in acute viral pharyngitis: A prospective, randomized, double-blind, placebo-controlled, multicenter study(Sage Publications Inc, 2010) Cingi, Cemal; Songu, Murat; Ural, Ahmet; Yildirim, Muzeyyen; Erdogmus, Nagehan; Bal, CengizWe conducted a prospective, randomized, double-blind, placebo-controlled, multicenter study to assess the efficacy of chlorhexidine gluconate/benzydamine HCl mouth spray for reducing pain and improving quality of life in patients with acute viral pharyngitis. Prior to treatment, patients rated the intensity of their pain on a visual analog scale and evaluated their quality of life on the 36-Item Short-Form Health Survey. Patients were then randomized to receive either paracetamol (acetaminophen) plus chlorhexidine/benzydamine or paracetamol plus placebo for 7 days. On days 3 and 7 of treatment, the participants again rated the intensity of their pain, and on day 7, they again rated their quality of life. A total of 164 patients were evaluable at study's end-80 in the chlorhexidine/benzydamine group and 84 in the control group. A comparison of self-evaluations revealed that the active treatment group reported less pain on both day 3 (p < 0.001) and day 7 (p = 0.002). Likewise, the chlorhexidine/benzydamine group reported a significantly better quality of life on day 7 (p < 0.001). Chlorhexidine/benzydamine was well tolerated, and no serious adverse events were observed.Öğe Is it necessary to accompany probing with endoscopy in cases of congenital nasolacrimal canal obstruction?(Elsevier Ireland Ltd, 2010) Cakmak, Sevin Soker; Yildirim, Muzeyyen; Sakalar, Yildirim Bayezit; Keklikci, Ugur; Alakus, FuatObjective To compare the results of probing with and without endoscopy in cases of congenital nasolacrimal duct obstruction who had previously not undergone probing Methods Fifty-one children with congenital nasolacrimal duct obstruction who underwent surgical intervention between June 2007 and April 2009 in our hospital were included in the study Patients who had had previous probings were excluded from the study. Conventional probing was performed in 37 eyes of 25 patients, and probing with intranasal endoscopic visualization in 36 eyes of 26 patients. Diagnosis was based on history of epiphora since birth or shortly after, and fluorescein dye disappearance test. Results Thirty-two of 37 eyes (86.48%) were cured by probing Of the 5 cases with complaints. I had lacrimal sac fistula. Thirty-four of 36 eyes (94.44%) were cured by probing guided by endoscope observation. Thirty-two cases had stenosis at the lower end of the nasolacrimal duct which required probing. In two cases the probe passed submucosally to the floor of the nose In two cases a false passage was made at the upper end of the inferior meatus In these cases, the operation was continued by repeating the process until the distal end of the nasolacrimal canal was seen to have been passed Conclusion Probing with endoscopy may be excessive in primary cases but in cases which have undergone unsuccessful probing, it is useful for visualization of anomalies in the lower nasolacrimal canal and to obtain the correct anatomic position for the probe (C) 2010 Elsevier Ireland Ltd All rights reserved.Öğe Is there Epithelial Tissue in Bone Pate? A Histopathology Study(Mediterranean Soc Otology & Audiology, 2012) Yorgancilar, Ediz; Firat, Ugur; Alabalik, Ulas; Gun, Ramazan; Yildirim, Muzeyyen; Bakir, Salih; Kinis, VefaObjectives: To evaluate the histology of bone pate collected during mastoidectomy in chronic suppurative otitis media (CSOM) patients with or without cholesteatoma. Study Design: Prospective controlled study. Materials and Methods: The study recruited 32 patients (15 males, 17 females; average age 25.3 (range 19-56 years) who underwent mastoidectomy for CSOM: 16 with cholesteatomas (group I) and 16 controls with granulation or polyp tissue (group II). In all patients, bone pate was collected separately from the mastoid cortex (Level 1), subcortical air cells (Level 2), and just before the antrum mastoideum (Level 3). All samples were stained with hematoxylin-eosin (H&E) and immunochemically with a monoclonal antibody against epithelial membrane antigen (EMA). The presence of squamous epithelium in the bone pate was examined under a light microscope. Results: In Group I, we detected epithelial cells in the bone pate samples obtained from the mastoid subcortex (two of 16 patients) and antrum (four of 16 patients) levels. However, no epithelial cells were observed in bone pate from the mastoid cortex. In the controls (group II), no epithelial tissue was observed in any sample from any level. Conclusions: Epithelial cells can inoculate bone pate collected from the subcortical and antral areas of the mastoid bone in patients with cholesteatomatous CSOM. To prevent epithelial cell inoculation, we recommended that bone pate be collected only from the cortical bone of the mastoid.Öğe Prevalence of allergic rhinitis among the adult population in Turkey(Informa Healthcare, 2010) Cingi, Cemal; Topuz, Bulent; Songu, Murat; Kara, Cuneyt Orhan; Ural, Ahmet; Yaz, Aytekin; Yildirim, MuzeyyenConclusion: The prevalence of self-reported and physician-diagnosed allergic rhinitis (AR) exhibits significant variability across the seven geographical regions in Turkey. Our findings may contribute to the formulation of public health policy and development of preventive and therapeutic strategies for AR in Turkey. Objective: The purpose of this study was to assess the prevalence of AR in the Turkish adult population, with emphasis on descriptive parameters in seven distinct geographical regions in Turkey. Methods: The volunteers were evaluated with a custom-designed questionnaire for AR. Sample size for the study was calculated by allowing for 2% error in prevalence along with a 95% confidence interval (CI). At the end of the study, we reached 4125 volunteers. The data were analyzed with chiÖğe Thyroid Nodule Demonstrating Itself as Calcified Lung Lesion(Derman Medical Publ, 2010) Yorgancilar, Ediz; Yildirim, Muzeyyen; Gun, Ramazan; Meric, Faruk; Topcu, IsmailMultinodular goiter (MNG) is the most prevalent thyroid pathology. Thyroid gland enlarge as a result of MNG, the initial extension is typically outward. After this cervical enlargement, expansion may extend in to the mediastinum. As substernal goiters enlarge within the mediastinum, vascular and visceral structures may slowly became compressed. The most common symptoms of substernal goiter result from compression of the trachea and/ or esophagus and include dyspnea, choking sensation, cough, and dysphagia. Progressive hoarseness and superior vena cava syndrome are less common symptoms. Substernal goiters can remain asymptomatic for many years and it may be diagnosed incidentally. For example, routine chest radiography may reveal a mediastinal mass or tracheal deviation. Many authors have advocated surgical removal of all substernal goiters, even when these goiters are asymptomatic. In this article, we report a case of substernal MNG which demonstrating itself as a nodular calcification on chest X-Ray radiography.Öğe Use of endocanalicular dacryocystorhinostomy with multidiode laser in children(Elsevier Ireland Ltd, 2010) Cakmak, Sevin Soker; Yildirim, MuzeyyenObjective: To evaluate the clinical outcome and efficacy of endocanalicular laser dacryocystorhinostomy using a multidiode laser in cases unresponsive to medical therapy, probing or intubation of pediatric nasolacrimal duct obstruction. Methods: Eight children with nasolacrimal duct obstruction were treated with a multidiode laser. The study was prospective, non-randomized, and noncomparative. The patients, 2 (25%) males and 6 (75%) females, ranged in age from 8 to 13 years (mean 11.25 +/- 2.43). Surgery was performed under general anesthesia. All procedures were performed using a multidiode laser. The nasal passage was visualized with a 30 degrees nasal video endoscope. In all cases, silicone stents were inserted. The main outcome measure was resolution or improvement of the epiphora and no major laser damage intranasally. Patients were followed for at least 6 months. Results: The endocanalicular laser dacryocystorhinostomy failed in one of the 8 (12.5%) cases, which had been secondary to trauma. The others were due to primary nasolacrimal duct obstruction. External dacryocystorhinostomy was performed on the failed case. None of the cases with primary nasolacrimal duct obstruction had obstruction after the endocanalicular laser dacryocystorhinostomy operation. Conclusions: Endocanalicular laser dacryocystorhinostomy using a multidiode laser appears to be an effective technique in cases unresponsive to medical therapy, probing or intubation of primary nasolacrimal duct obstruction. (C) 2010 Elsevier Ireland Ltd. All rights reserved.