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Öğe Accelerated corneal collagen cross-linking for progressive keratoconus(Taylor & Francis Ltd, 2014) Cinar, Yasin; Cingu, Abdullah Kursat; Turkcu, Fatih Mehmet; Yuksel, Harun; Sahin, Alparslan; Yildirim, Adnan; Caca, IhsanPurpose: To evaluate the efficacy of accelerated corneal cross-linking (CXL) procedure for progressive keratoconus. Materials and methods: Twenty-three eyes of 23 patients undergone accelerated CXL procedure were evaluated preoperatively and postoperatively at 1st, 3rd and 6th month for uncorrected distant visual acuity (UDVA), best corrected distant visual acuity (CDVA), spherical error, cylindrical error, spherical equivalent (SE), keratometric values and thinnest corneal thickness (TCT) values with corneal topography by Scheimpflug camera and endothelial cell density (ECD). Results: The mean UDVA was improved from 0.97 +/- 0.41 logarithm of minimal angle of resolution (logMAR) to 0.76 +/- 0.45 logMAR at the 6th month after CXL (p = 0.332). The mean CDVA was improved from 0.49 +/- 0.30 logMAR to 0.34 +/- 0.22 logMAR at the 6th month after CXL (p = 0.026). The mean sphere was decreased from -4.47 +/- 4.1 diopter (D) to -3.79 +/- 3.86 D and the mean cylinder was decreased from -5.60 +/- 2.2D to -4.55 +/- 1.98 D and the mean SE was decreased from -7.22 +/- 4.48 D to -6.36 +/- 4.34 D at the 6th month after CXL (p = 0.128, p = 0.002 and p = 0.045, respectively). Flat keratometry, steep keratometry, mean keratometry and maximum keratometry were significantly reduced at the 6th month after CXL (p = 0.025, p < 0.001, p = 0.004 and p = 0.03, respectively). TCT and ECD were not changed significantly the 6th month after CXL (p = 0.135 and p = 0.082, respectively). Conclusion: Accelerated CXL procedure was effective to stabilize progression of keratoconus with significant reduction in topographic keratometric values and significant increase in CDVA in 6 months.Öğe Diagnosis of Malignant Hypertension with Ocular Examination: A Child Case(Informa Healthcare, 2014) Yildirim, Adnan; Turkcu, Fatih Mehmet; Yuksel, Harun; Sahin, Alparslan; Cinar, Yasin; Caca, IhsanA 12-year-old female patient was admitted to our clinic complaining about low vision. Bilateral optic disc edema, macular star, and preretinal hemorrhages were found in fundoscopic examination. In fundus fluorescein angiography, massive leakage in the late phase was seen in the optic nerve head and macular area. These findings were compatible with high-grade hypertensive retinopathy. The patient consulted with pediatrics and a diagnosis of vesicourethral reflux and malignant hypertension was made.Öğe Evaluation of choroidal thickness in psoriasis using optical coherence tomography(Springer, 2016) Turkcu, Fatih Mehmet; Sahin, Alparslan; Yuksel, Harun; Akkurt, Meltem; Ucmak, Derya; Cinar, Yasin; Yildirim, AdnanThe purpose of this study was to evaluate choroidal thickness (CT) in patients with psoriasis using enhanced depth imaging optical coherence tomography (EDI-OCT) and to determine its relationship with psoriasis activity indices. In this prospective study, EDI-OCT images were obtained in consecutive patients with psoriasis and in age-gender-matched healthy individuals. Comprehensive ophthalmic examination and EDI-OCT evaluation were performed. CT was measured in the subfoveal area. Correlation analyses were performed to identify the relationship of the CT with disease duration and clinical disease activity score. In total, 65 individuals were evaluated in this study, 35 with psoriasis and 30 controls. The mean disease duration of the patients with psoriasis was 15.7 +/- 8.8 years (0.3-34 years). There was no difference between groups with respect to age and gender (p = 0.695 and p = 0.628, respectively). Five of the 35 patients with psoriasis had anterior uveitis. None of the patients with psoriasis had signs of posterior uveitis. CT was significantly higher in the psoriasis group than that of control subjects (p < 0.001). The mean central foveal thickness was comparable between groups (p = 0.672). There was also no significant correlation between EDI-OCT, disease activity score, and disease duration (p < 0.05). Choroidal thickness is increased in psoriasis patients. Large serial and comparative studies are necessary to evaluate EDI-OCT, an examination that may be helpful in understanding the effects of psoriasis on the eye and its pathophysiology.Öğe Impact of Collagen Cross-linking on Psychological Distress and Vision and Health-Related Quality of Life in Patients With Keratoconus(Lippincott Williams & Wilkins, 2015) Cingu, Abdullah Kursat; Bez, Yasin; Cinar, Yasin; Turkcu, Fatih Mehmet; Yildirim, Adnan; Sahin, Alparslan; Tas, CumaObjective: To evaluate the changes in psychological distress level and quality of life (QoL) scores of keratoconus (KC) patients 1 year after corneal collagen cross-linking (CXL). Methods: Observational cross-sectional study. Thirty-three, consecutive progressive KC patients who received CXL treatment were enrolled in the study. All patients were evaluated before and 1 year after CXL ophthalmologically and psychologically. Main outcome measures were the visual, refractive, and topographic changes and the Beck Depression Inventory, State-Trait Anxiety Inventory (STAI), Short Form-36 (SF-36), and The National Eye Institute Visual Function Questionnaire (NEI-VFQ-25). Results: There were significant improvements in the keratometric readings at flat axis, steep axis, the mean keratometric reading, the corneal astigmatism (K-ast), and the maximum keratometric reading. State-Trait Anxiety Inventory-II scores, QoL dimensions, such as physical role difficulty, general health, mental health, ocular pain, near activities, distance activities, peripheral vision, and mental health scores, and the composite score of NEI-VFQ-25, were higher after surgery. There was a positive correlation between the changes observed in K-ast and mental health; a negative correlation between the changes in K-ast and STAI-II, and a negative correlation between the changes in mental health and STAI-II. Change in STAI-II has significantly predicted the improvement observed in general health. Conclusions: Our results suggested lower trait anxiety and better vision-related and health-related QoL in KC patients 1 year after successful CXL treatment. Better QoL in these patients seems to be related not only with the visual and refractive results but also improvement observed in trait anxiety.Öğe Response: comment on: mean platelet volume in patients with retinal artery occlusion(Consel Brasil Oftalmologia, 2016) Sahin, Muhammed; Sahin, Alparslan; Yuksel, Harun; Turkcu, Fatih Mehmet; Yildirim, Adnan[Abstract Not Available]Öğe Response: comment on: mean platelet volume in patients with retinal artery occlusion(Consel Brasil Oftalmologia, 2016) Sahin, Muhammed; Sahin, Alparslan; Yuksel, Harun; Turkcu, Fatih Mehmet; Yildirim, Adnan[Abstract Not Available]Öğe Retinopathy of prematurity screening with mobile phones(Wichtig Publishing, 2016) Sahin, Alparslan; Turkcu, Fatih M.; Yildirim, Adnan[Abstract Not Available]Öğe Spontaneous bilateral corneal perforation in a patient with ichthyosis(Springer, 2014) Cinar, Yasin; Selcuk, Caferi Tayyar; Cingu, Abdullah Kursat; Turkcu, Fatih Mehmet; Yuksel, Harun; Yildirim, Adnan; Cinar, TubaWe present an 8-month-old female patient with bilateral spontaneous corneal perforation and lamellar ichthyosis. On examination, the skin of the body and face of the patient was completely dry and scaly. Cicatricial ectropion and descemetocele with small perforations were seen. Double-layered amniotic membrane transplantation on the cornea with eyelid construction was performed on both eyes. At the 6-month follow-up, lower eyelid minimal ectropion formation and inferior corneal leukoma were seen bilaterally. In ichthyosis patients, the cornea should be monitored closely due to the risk of severe visual loss and corneal perforation.
