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    Blood glucose fructosamin and HbAlc levels in cases with diabetes mellitus
    (1992) Yenice N.; Kaplan A.; Batun S.; Canoruc N.
    In this research serum glucose, fructosomin and erytroid HbAlc levels were investigated in 50 patiens with diabetes mellitus (Type I and II) and result were compared with the normal control values. (25 normal people) In the control group the levels of serum glucose, fructosamin and erytroid HmAlc were obtained as % 94.52 ± 7.7 mg; 2.29 ± 0.299 mmol/L; % 7.02 ± 0.742 respectively. In cases with Diabetes mellitus the levels of serum glycose, fructosamin and erytroid HbAlc were obtained as % 270.83 ± 98.49 mg, 4.02 ± 0.942 mmol/L, % 13.09 ± 2.387 respectively. The levels of serum glucose, fructosamine and erytroid HbAlc were increased significantly in patients with diabetes mellitus as compared with control group (p < 0.001). The serial determinations of serum fructozamin and erytroid HbAlc levels are of value in cases with diabetes mellitus in the diagnosis, treatment and in estimation of complications of diabetes mellitus which will appear in future.
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    Öğe
    Nitrendipine and stress-induced ulcers: Preliminary tudy
    (1997) Inalöz S.; Ozaydin M.; Sari I.; Cicek R.; Guney B.; Yenice N.
    Nitrendipine is a derivative of the dihydropyridine of calcium channel blockers and released for angina and hypertension. The therapeutic effect of nitrendipine was observed histologically against stress-induced gastric and duodenal ulcers in rats. Twenty-four male Wistar-albino rats were separated into three groups (n = 8), a control (non-stress) and two stress groups. The stressed group rats were exposed to starvation and cold-restraint in this study. The first stress group was given only a placebo whereas the second stress group was treated with nitrendipine. After treatment with nitrendipine, the total rea of the affected lesional mucosa was considerably reduced in both duodenal and gastric mucosa. Macroscopically, the surface area of the affected lesional mucosa was measured as 1/5 of the total duodenal mucosa. Moreover, the surface area of the affected lesional mucosa was measured as 1/8 of the total surface area in the stomach. In microscopic examination, tissue regeneration was conspicuous particularly in the gastric epithelium. A few hyperchromatic epithelial cells were noticed in some fields of the duodenal mucosa. Furthermore, tissue regeneration was not conspicuous as in the gastric mucosa. So we think that nitrendipine can be used in both gastric and duodenal stress ulcer treatment. However, in the healing process, therapeutic effect of nitrendipine was superior in stomach with conspicuous tissue regeneration.