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    900 MHz radiofrequency radiation has potential to increase the expression of rno-miR-145-5p in brain
    (University of Dicle, 2019) Dasdag S.; Erdal M.E.; Erdal N.; Tasdelen B.; Kiziltug M.T.; Yegin K.; Akdag M.Z.
    Interaction between radiofrequency radiation (RFR) and miRNA which plays paramount role in growth, differentiation, proliferation, and cell death by suppressing one or more target genes, is still unknown. Therefore, the purpose of this study is to investigate the effects of long term 900 MHz mobile phone exposure on some of the miRNA in brain tissues (sham: 7; Exposure: 7)., which were kept in appropriate laboratory conditions for the second phase of our previous study [5]. It is remembered that rats in the exposure group were exposed to 900 MHz RFR for 3 h per day (7 days a week) for one year. For the aim of this study, expression of miRNAs such as rno-miR-22-3p, rno-miR-24-1-3p, rno-miR-132-3p, rno-miR-145-5p, rno-miR-181a-5p, rno-miR-186-5p, rno-miR-195-5p, rno-miR-219a-5p, rno-miR-221-3p and rno-miR-222-3p were investigated. Results indicated that long-term exposure of 900 MHz RF radiation increased only expression of rno-miR-145-5p (adj P * = 0.047) value where 1g average SAR value in brain was 0.198 W/kg. Our results indicated that chronic exposure of 900 MHz RFR has potential to increase expression of rno-miR-145-5p. Therefore, further studies are necessary to understand the relation between 900 MHz mobile phone exposure and diseases related to the expression of rno-miR-145-5p. © University of Dicle.
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    Öğe
    Effect of mobile phone signals on electrical impulses of myelinated nerve fibres
    (University of Dicle, 2017) Yegin K.; Yegin E.G.; Dasdag S.
    One of the seldom studied effects of mobile phone radiation is its impact on impulse transmission in nerve fibers. Effects could be; although unlikely, stimulation of a nerve pulse, change in depolarization threshold rest potentials, conduction velocity, and energy spectrum of the impulse. To study these effects, 3D electromagnetic field distributions inside a volumetric pixel model of a human were simulated with a GSM antenna in proximity of hand. The electric field and SAR distributions due to a radiating antenna 10 mm away from hand were calculated for 0.8 W and 2 W peak pulsed GSM signals at 900 MHz. Maximum SAR in the hand was found to be 5.78 W/kg for 10 g average and 8.21 W/kg for 1g average. As the depth from skin surface increases, the probe readings can get as high as 20 mV and as low as 1 mV for 2-W peak-power transmission. Coupled signal voltage waveform along a myelinated nerve fibre was calculated and superimposed on nerve impulse at four different instances. Spectrums of the resulting impulse with and without GSM coupling were also compared to each other. The noise floor in the spectrum of the nerve impulse has increased due to presence of GSM signal. It was observed that GSM-signal coupling could distort the shape and the spectrum of the nerve impulse, but it did not reach a level to trigger an impulse from its resting potential nor perturb the nerve conduction velocity if only the induced electrical force is considered.