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Öğe Can the Density of Mineralized Dental Tissues (Dentin and Enamel) Be Measured and Compared with 3D Cone Beam Computed Tomography in Cases of Ectodermal Dysplasia?(Int Scientific Information, Inc, 2022) Yavuz, Yasemin; Akleyin, Ebru; Dogan, Mehmet Sinan; Goncharuk-Khomyn, Myroslav; Akkus, ZekiBackground: Since 3-dimensional cone beam computed tomography (CBCT) started to be used in dentistry, mineral density can now be examined with computer software from the data on the images obtained. Detailed and clear im-ages at different slice intervals can be obtained with CBCT, and mineral density can be measured from the im-age data on a computer with a Hounsfield unit (HU) scale. In addition to the broad opportunities presented by CBCT, this feature has presented a wider perspective to researchers. Material/Methods: In this study, the CBCT images obtained from patients with the genetic disorder of ectodermal dysplasia were compared with the images of a control group to determine differences in mineralization of the teeth and to show that these could be compared by measuring the mineral density of dentin and enamel tissues using the HU scale on data from CBCT images. This opens new opportunities for cognitive and implementation research. Results: In the study, CBCT images of 14 ectodermal dysplasia and 14 control group cases previously obtained for vari-ous reasons were used. Mineral density measurements were made from 4 different regions of the teeth of the ectodermal dysplasia and control groups (incisor edge of the crown, the center buccal, cervicale line, and apex of the teeth), and the groups were compared. Conclusions: The aim of this study was to provide a new overview of the feasibility and suitability of mineralization mea-surement of dentin and enamel dental tissues with CBCT in ectodermal dysplasia and control groups.Öğe Clinical and radiological findings, SEM analysis and evaluation of caries risk in ectodermal dysplasia cases(Taylor & Francis, 2022) Yavuz, Yasemin; Akleyin, Ebru; Akdağ, Mehmet Zülküf; Çolak, Mehmet; Doğan, Mehmet Sinan; Kotanlı, SedefEctodermal dysplasia (ED) consists of many different combinations of irregularities that include developmental defects that occur in two or more of the following tissues: teeth, nails, skin, hair and sweat glands. The aim of this study was to evaluate the possible carries risk, perform scanning electron microscopy (SEM) mineral analysis in ectodermal dysplasia cases and describe the oral aspects. Ectodermal dysplasia cases, 41 patients (22 males and 19 females, aged 1.5 to 45 years), had a clinical examination. SEM analyses were performed from teeth that had to be extracted from ED cases for various reasons. Forty-one patients had tooth agenesis (from hypodontia to anodontia), multiple caries, hair and nail dystrophy. Also, extra orally they had sparse or absent hair, a short face, an unusual facial concavity, maxillary retrusion and relative mandibular protrusion. Differences between tooth samples were determined by SEM analyses. SEM analyses showed that the mineral content of ED teeth was lower than that of normal teeth and the surface properties of dentin and enamel were different. It is necessarily to support this observation with more comprehensive research. When dentists examine ED patients, they should consider the oral mucosa for excessive dryness and increased dental caries and should conduct a comprehensive, multidisciplinary approach to these patients in order to improve their dental, masticatory and caries conditions.Öğe Çürük Nedeniyle Dişlerin Mineralize Dokularında oluşan Kayıplar KIBT ile Kantitatif Olarak Ölçülebilir mi?(Harran Üniversitesi, 2022) Yavuz, Yasemin; Akleyin, Ebru; Akkuş, Zeki; Doğan, Mehmet EminBilindiği gibi günümüzde diş hekimliğinde yaygın olarak kullanılmaya başlanılan üçboyutlu konik ışınlı bilgisayarlı tomografiler (KIBT) ile elde edilen görüntülerde bilgisayarortamında Hounsfield units (HU) skalası yardımıyla sert dokularının mineral yoğunluklarıölçülebilmektedir. Çalışmamızda çeşitli nedenlerle elde edilmiş olan KIBT tarama görüntülerindenseçilmiş olan 15 çürük dişte çürük ve sağlıklı mine-dentin dokularından elde edilen HUskalası ölçüm değerleri karşılaştırılmıştır.Bu öncül çalışmada, çürük diş mine ve dentin dokularının mineralizasyon yoğunlukölçümünün yapılabilirliği bu sayede çürük dişlerin kantitatif değerler ışığındakarşılaştırılabileceği belirlenmiştir. Ancak KIBT görüntüleri elde edilirken hastanın yüksekradyasyon dozlarına maruz kalmasından dolayı günümüz için çürük tespitinde klinikmuayene ve geleneksel görüntüleme yöntemlerinin yeterli olduğu düşünüldü.Öğe Effect of electromagnetic fields and antioxidants on the trace element content of rat teeth(Dove Medical Press Ltd, 2017) Dogan, Mehmet Sinan; Yavas, Mehmet Cihan; Yavuz, Yasemin; Erdogan, Sait; Yener, Ismail; Simsek, Ibrahim; Akkus, ZekiThe purpose of this study was to examine the possible effect of extremely low-frequency electromagnetic fields (ELF-EMFs), from a high-voltage source, on rat teeth in terms of changes in trace elements (TEs) and the effect of antioxidants (melatonin [MLT] and Ganoderma lucidum [GL]) in counteracting these effects. We used adult male Wistar albino rats with a mean weight of 250-300 g and divided the rats into eight groups. The groups were subjected to an ELF- EMF that was applied with a high- voltage line for 8 hours/day for 26 days (Groups I, II, and III) or 52 days (Groups V, VI, and VII). Groups IV and VIII were the 26- and 52- day control/sham groups, respectively. Groups II and VI were treated with GL, and Groups III and VII were treated with MLT. MLT and GL were administered daily based on the weight of the animals and appropriate standards. At the end of the study, the rats were euthanized, and their anterior teeth were extracted. The teeth were preserved in pure water before evaluating the major TEs. At the end of the study, TE concentrations (in mg/kg) were assessed in the control and test groups. Compared with Group V, statistically significant differences in the concentrations of zinc (Zn) and strontium (Sr) were found for Group VII (ELF- EMF + MLT) (P< 0.05). Therefore, ELF- EMF exposure can change the content of certain TEs in teeth and, after administering MLT and GL, the values of some of the TEs return to normal.Öğe Effects of Chlorhexidine Gluconate and Ozone on Bond Strength(Univ Indonesia, Fac Dentistry, 2018) Yavuz, Yasemin; Bahsi, EmrullahObjective: To examine the effects of chlorhexidine gluconate (Chx) and ozone on the bond strength of currently used restorative materials to dentin. Methods: Ninety third molar teeth were randomly divided into three groups of 30 each. Samples in Groups 1 and 2 were disinfected with Chx and ozone, respectively, whereas those in Group 3 were not disinfected (controls). Subsequently, the samples in all three groups were further divided into three subgroups of 10 teeth each and restored with Filtek Silorane (a), Gradia Direct (b), or Quixfil (c). Shear force was applied to the samples at 1 mm/min until breaking point. Fracture types were determined by examining the broken surfaces under a stereomicroscope. Results: No significant differences in bond strengths were noted between the Chx and control groups. However, the bond strengths in the ozone subgroups were found to be significantly lower than that of the control subgroups (p < 0.05). Adhesive type fractures were observed in majority of the treatment groups. Conclusion: As Chx did not affect the shear bond strength of the restorative materials, it may be considered for use as a cavity disinfectant before restoration; conversely, ozone should be used with caution for cavity disinfection.Öğe Evaluation of clinical and oral findings in patients with epidermolysis bullosa(Multidisciplinary Digital Publishing Institute (MDPI), 2023) Yavuz, Yasemin; An, İsa; Yazmacı, Betül; Akkuş, Zeki; Ortaç, HaticeIntroduction: Epidermolysis bullosa (EB) is a genetically inherited disease characterized by recurrent bullae and erosions on the skin with numerous signs of dental caries and poor oral hygiene. The aim of this study was to investigate the general clinical and oral findings of patients with EB. Materials and Methods: In this prospective study, the clinical and oral findings and family history of 26 cases with EB were evaluated. The type of EB, gender, age, parental consanguinity, dental caries, oral findings, distribution of lesions and presence of associated anomalies, clinical and oral findings correlated with gender were recorded. Results: All 26 patients with EB had a history of consanguinity and siblings with EB to varying degrees. In our study, malnutrition, anemia and growth retardation, gastrointestinal system complications, hair thinning, hand and nail deformity, ocular problems and renal disease (in one case) were observed with variable frequencies. When the intraoral findings of the patients were investigated, extensive dental caries in all EB types, enamel hypoplasia in junctional EB (JEB) and the presence of tooth-root to be extracted in dystrophic EB (DEB), intraoral bullae and lesions, ankyloglossia, vestibular sulcus insufficiency, microstomia and maxillary atrophy were observed. Three cases had restorative treatment and one case had prosthetic rehabilitation. Conclusions: Oral involvement can be seen with varying frequencies depending on the type of EB and the severity of the disease. It may result from delayed oral and dental rehabilitation due to physical disabilities, limitations and more pressing medical problems. Microstomy, pain from mucosal lesions, and restricted access to the mouth can be caused by poor oral hygiene. Oral complications and caloric needs of individuals with EB should be determined, and individual prophylaxis should be applied to prevent caries formation and protect teeth.Öğe Evaluation of ectodermal dysplasia(Elsevier (Singapore) Pte Ltd, 2006) Başkan, Zelal; Yavuz, İzzet; Ülkü, Refik; Kaya, Sadullah; Yavuz, Yasemin; Başaran, Güvenç; Adıgüzel, Özkan; Özer, Torun; 0000-0001-6953-747X; 0000-0001-6953-747X; 0000-0001-6089-3013This case series report outlines possible cranio-maxillofacial deformation consequences associated with ectodermal dysplasia (ED) and embryonic malformations, including dental agenesis. Also described are the oral aspects and rehabilitation. A total of 14 ED patients (7 males and 7 females, aged 5-45 years) underwent clinical examination before assessment and treatment. Lateral cephalometric radiography, Steiner's analysis, and respiratory capacity tests were performed. Most of the patients had sparse or absent hair, a short face with an unusual facial concavity, a maxillary retrusion, and a relative mandible protrusion. Depending on age and orthopedic abnormalities, patients were treated with prosthodontic and orthodontic approaches or implant treatment. Therapists should take a comprehensive and multidisciplinary approach with these patients to improve their dental, masticatory, growth, and orthognathic conditions, as well as esthetic appearance.Öğe Evaluation of radiation exposure due to dental radiographs taken during endodontic treatment sessions in young permanent teeth(MDPI, 2022) Akleyin, Ebru; Yavuz, YaseminBackground and Objectives: The aim of this study was to retrospectively analyze the duration of treatment and the number of dental radiographs taken during endodontic treatment (endo-t) of young permanent teeth (YPT). Materials and Methods: Age, gender, affected tooth number, apex status, duration of treatment and dental radiographs taken during this period were retrospectively evaluated in pediatric patients aged 6–15 years who presented to the pedodontic department for endo-t of anterior YPT. Data were analyzed with Kruskal Wallis H, Dunn and Pearson chi-square tests. p < 0.05 was accepted as statistically significant in all analyses. Results: Anterior endo-t was initiated in 471 of 9,200 pedodontic patients between the ages of 6 and 15 years who applied to our university. The reason for seeking treatment was caries (8.1%) and trauma (91.9%). It was observed that 59% of the teeth had an open apex and 45.7% had a closed apex. A total of 1893 periapical radiographs (Per-R) and 245 panoramic radiographs (Pan-R) were taken from 471 pediatric patients during the treatment period. Total number of dental radiographs was 2138 with 4.5 per patient. Number of Per-R was lower in patients whose treatment was completed in a single session (p < 0.001). There was no difference in the number of Pan-R with respect to duration of treatment (p = 0.560). Conclusions: In children, the number of Per-R significantly increased with prolonged duration of treatment encompassing multiple sessions for endo-t procedures of anterior YPT, decided based on the apex and lesion status of the affected tooth. Especially in long-term traditional apexification treatments, treatment should be carried out in children with the ALADAIP (As Low As Diagnostically Achievable being Indication-oriented and Patient-specific) principle in mind.Öğe Evaluation of stress distribution of a new restorative material and composite resin: a finite-element analysis study(Taylor & Francis Ltd, 2017) Dogan, Mehmet Sinan; Demirci, Fatih; Eratilla, Elif; Eratilla, Veysel; Yavuz, Yasemin; Unal, MehmetGlass carbomer cement is a new dental material developed from the traditional glass ionomer cements. It has better mechanical and chemical features when compared to the conventional glass ionomer cements. The purpose of this in silico investigation was to examine the influence of glass carbomer and composite resin materials with class I cavity design on stresses happening in the inlay. Finite-element analysis and three-dimensional modelling were used to examine the stress in the glass carbomer and hybrid composite inlays resulting from a 300-N point load on occlusal surfaces. Two different inlay materials, glass carbomer cement and hybrid composite resin, were evaluated. The maximum von Misses stress values in the composite resin inlays were significantly lower than those in the glass carbomer inlays. The results from this study showed that the resistance of the glass carbomer against the forces was higher than that of the composite resin inlays. The stresses were concentrated mostly at similar regions. The obtained results suggest that glass carbomer may be recommended as a preferred filler restorative material in teeth with much structure loss.Öğe Geleneksel kavite dezenfektanı ve ozonun, güncel restoratif materyal uygulanmış dişlerde makaslama bağlanma dayanımına etkisi(2015) Yavuz, Yasemin; Bahşi, EmrullahAmacı; Enfekte dentinin mekanik uzaklaştırılması sonrası kavitede ve smear tabakasında kalması muhtemel mikroorganizmaların eliminasyonu amacıyla kullanılan kavite dezenfektanı klorheksidin glukonat ve ozonun, güncel restoratif materyallerde (kompozit, siloran) dentine bağlanma dayanıklılık etkisinin incelenmesidir. Materyal ve metot; Çalışmamızda 90 adet çürüksüz, restorasyonsuz üçüncü molar diş kullanıldı. Dişler dentin yüzeyi yere paralel olacak şekilde 2 cm çapında, 3 cm boyunda silindirik kalıplara kökleri içinde kalacak şekilde soğuk akril yardımıyla yerleştirildi. Orta koronal düz dentin yüzeyleri elde edilinceye kadar aşındırıldı. Örnekler rastgele üç ana gruba (n=30) ayrıldı. Her bir grup daha sonra kendi içinde rastgele üç alt gruba (n=10) ayrıldı. Ana gruplardan birincisine dentin yüzeylerine klorheksidin (Ceraxidin-C), ikincisine ozon (Prozone ) uygulandı, üçüncü grup ise kontrol grubu olarak hazırlandı. Alt gruplardaki örneklerin dentin yüzeylerine çapı 3 mm, yüksekliği 4 mm olan silikon şeffaf kalıplar içerisine üç farklı restoratif dolgu materyali kullanılarak restore edildi (Filtek Silorane, Gradia Direct, Quıxfil). Kontrol gruplarına dezenfeksiyon işlemi uygulanmadan restorasyon tamamlandı. İnstron universal test cihazına yerleştirilen örnekler 1 mm/dak. hızda makaslama kuvveti uygulanarak kırılıncaya kadar kuvvet uygulandı. Elde edilen değerler MPa cinsinden kaydedildi. Kırılan yüzeyler, x40 büyütmede stereo mikroskopta incelenerek kırık tipleri tespit edildi. Bulgular: Çalışmamızın istatistiksel değerlendirilmesinde Veriler Kolmogorov-Smirnov testine göre normal dağılış göstermediğinden tüm grupların karşılaştırılmasında Non-parametrik testlerden Kruskal Wallis varyans analiz yöntemi uygulandı. Grupların kendi aralarında ikişerli karşılaştırmalarında ise çoklu karşılaştırma testlerinden Bonferroni Düzeltmeli Mann-Whitney U testi kullanıldı. Çalışmanın makaslama bağlanma dayanımı incelenmesinde gruplar arasındaki farklılık istatistiksel olarak anlamlı bulunmuştur (P<0,05). Sonuç: Kavite dezenfeksiyonu amacıyla uygulanan klorheksidinin restoratif materyallerin makaslama bağlanma dayanımını kontrol gruplarıyla karşılaştırıldığında istatistiksel olarak etkilemediğinden restorasyon öncesinde kullanılabileceği sonucuna varıldı. Ozon uygulamasının makaslama bağlanma dayanımı kontrol gruplarıyla karşılaştırıldığında istatistiksel olarak anlamlı düşüş görüldü. Bu nedenle restoratif tedaviler öncesi kavite dezenfeksiyonu amacıyla ozon uygulamasına kuşkuyla yaklaşılmalı ve sebeplerinin araştırılması için ileri in vitro/ in vivo deneysel ve klinik çalışmalara ihtiyaç duyulmaktadır.. Anahtar Kelimeler: Ozon, klorheksidin, bağlanma dayanımı, kompozitÖğe Mineral Density Distribution Differences in Enamel and Dentin Tissues in the Teeth Array According to the HU Scale(Assoc Apoio Pesquisa & Saude Bucal-Apesb, 2023) Yavuz, Yasemin; Akleyin, EbruObjective: To evaluate the mineral density of enamel and dentin tissues of healthy individuals using three-dimensional cone-beam computed tomography. Material and Methods: CBCT images of 15 healthy individuals, previously obtained for various reasons, were used in this study. In HU measurements, mineral density measurements were made from three different regions of enamel and three different regions of dentin, and the values obtained were compared. Enamel and dentin mineralization density measurements were measured from six regions, namely the crown cutting edge, buccal middle and cervical region for enamel, and the crown cutting edge, cervical region and root apex for dentin. In the comparisons of groups, the parametric One-Way ANOVA variance analysis method was applied. In the paired comparisons between the groups, the Tukey HSD test was applied as the multiple comparison post hoc test. A value of p<0.05 was accepted as statistically significant. Results: Mineralization density of tooth enamel and dentin tissues was quantitatively different in the maxilla and mandible in anterior and posterior teeth. Conclusion: In all the teeth, there were statistically significant decreases in the mineral density values of enamel and dentin tissue from occlusal towards the cemento-enamel junction. Statistically significant decreases were observed in the mineral density values of enamel and dentin tissue from the anterior region towards the posterior region in the teeth in both the upper and lower jaws.Öğe Three-Dimensional Modeling and Quantitative Assessment of Mandibular Volume in Ectodermal Dysplasia: A Case Series(Mdpi, 2024) Akleyin, Ebru; Yavuz, Yasemin; Yardimeden, AhmetBackground and Objectives: Ectodermal dysplasia (ED)-a genetic disorder-is characterized by severe tooth deficiency. We compared the mandibular volume and the sagittal and horizontal mandibular widths between patients with ED (ED group) and individuals without tooth deficiency (control group) using three-dimensional modeling. We hypothesized that the mandibular volume differs in ED cases owing to congenital tooth deficiency. Materials and Methods: We used previously obtained cone-beam computed tomography (CBCT) images of 13 patients with ED. The control group data comprised retrospective CBCT images of patients of similar age and sex with a skeletal relationship of class 1. Further, using the three-dimensional image analysis software, the tooth crowns were separated from the mandible, the mandible was reconstructed and the gonion-to-gonion distance in the mandible was marked, the distance to the menton point was measured, and the distance between the two condyles was measured and compared with the control group. Results: Overall, 46.2% and 53.8% of the participants were men and women, respectively. In the ED group, the mean age of the participants was 15.46 (range, 6-24) years, and the mean number of mandibular teeth was 4.62. Notably, the edentulous mandible volume of the ED group (27.020 mm(3)) was statistically significantly smaller than that of the control group (49.213 mm(3)) (p < 0.001). There was no difference between the two groups in terms of the marked points. For data analysis, the Shapiro-Wilk test, independent samples t-test, and Mann-Whitney U test were used. Conclusions: It has been considered that mandible volume does not develop in ED cases because of missing teeth. Modern practices, such as the CBCT technique and three-dimensional software, may be effective in identifying the true morphologic features, especially in patients with genetic syndromes affecting the maxillofacial structure.