Yazar "Yavuz, D." seçeneğine göre listele
Listeleniyor 1 - 5 / 5
Sayfa Başına Sonuç
Sıralama seçenekleri
Öğe CD34 expression of chorionic villous in pre-eclamptic placenta: an immunohistochemical and ultrastructural study(I R O G Canada, Inc, 2013) Kalkanli, S.; Deveci, E.; Sak, M. E.; Evsen, M. S.; Baran, O.; Ozekinci, S.; Yavuz, D.In this study, pre-eclampsia, proteinuria, and edema associated with hypertension in pregnancy were assessed at the Dicle University School of Medicine Department of Obstetrics and Gynecology Clinic. One group included 20 pre-eclamptic pregnant women with gestational age 20-35 weeks of pregnancy and the same in the control group that included; however, 20 normotensive pregnant women. Histochemistry, immunohistochemistry, and electron microscopy techniques were used. Histopathological examination of syncytial nodes and stromal cells were observed in the increase in hyperplasia and hyalinization. The evaluation immnunohistochemical of chorionic villi, placenta, and hematopoietic stem cell markers showed a positive reaction with CD34. Ultrastructural examination showed endoplasmic reticulum dilatation, degeneration of mitochondria in endothelial cells, and capillary vessel edema.Öğe EFFECTS OF MANGANESE ETHYLENE-BIS-DITHIOCARBAMATE (MANEB) ON RAT NASAL RESPIRATORY MUCOSA(Carbone Editore, 2013) Deveci, E.; Yorgancilar, E.; Ekinci, C.; Koparal, M.; Akkus, Z.; Yavuz, D.Maneb (Mn-ethylene(bis)dithiocarbamate is a dithiocarbamate pesticides. It is a fungicide pesticide used in the control of mildew disease on certain crops. In general, dithiocarbamates are considered chemicals of low toxicity for humans. However, the effects of maneb in humans are diverse. It has some effects to humans via absorption through skin and respiratory system. The nasal mucosa is the first part of the airways in contact with the environment and toxic agents. The aim of this study was todetermine the histopathological effects of numb on nasal mucosa. In experimental group, the maneb was administered with inhalation to 10 male Wistar-Albino rats for five days a week. The control group (n=10) received distilled water with spray at the same time period. The experiment was terminated after three weeks. In each case, sections of the nosewere taken. In experimental group,microscopic examination of nasal respiratory mucosa revealed; Hypertrophy of epithelial cells and goblet cells, increasing of mucus secretion, decreasing in sizes of cilia and flattening of the cells near the basement membrane and apoptotic cells in the degenerated respiratory epithelial cells, detected a mild inflammatory reaction and a vascular dilatation in the connective tissue. All changes were statistically significant. In control group of 10 rats no significant histopathologic lesions were found. As a result, our study, maneb is potentially toxic agent to respiratory mucosa.Öğe Expression of Human Chorionic Gonadotropin (?hCG) in Pre-eclamptic Placenta(Soc Chilena Anatomia, 2015) Ekinci, C.; Tahaoglu, A. E.; Balsak, D.; Deveci, E.; Yavuz, D.; Togrul, C.; Karaman, E.This study aimed to assess association between preeclampsia with trophoblast cells and serum level of b-human chorionic gonadotropin (beta-hCG). Were compared 20 patients with preeclampsia and 20 control patients with respect to demographics, hematological parameters and the presence of trophopblast in placental samples. Patchy necrosis with loss of microvilli and gross thinning of the syncytium with distorted microvilli were seen in terminal villi of placentae of women with pre-eclampsia Syncytial cells at the molecular level crossings, especially at the level of beta hCG in conjunction with the changes in the preeclampsia was made on the histopathological changes to clarify the villi.Öğe Expression of VEGF and CD68 in the Placenta of Gestational Diabetic Mothers (Immunohistochemistry and Ultrastructural Study)(Soc Chilena Anatomia, 2015) Yavuz, D.; Balsak, D.; Ekinci, C.; Tahaoglu, A. E.; Togrul, C.; Goruk, N.; Aktas, A.Placental angiogenesis, is essential for embryonic and fetal development. In this study, 18 gestational diabetes mellitus and 22 control pregnancies were included. Gestational diabetes mellitus (GDM) groups compared to the control group significantly higher values were detected (p<0.01). The following histological results were assessed; villous immaturity, chorangiosis, presence of, sncytial knots, mononuclear cell infiltration ischemia and fibrinoid necrosis. To evaluate and compare the placental histology of normal and GDM pregnancies. placentas of pregnant women with gestational diabetes also in terms of angiogenesis and macrophages and ultratructural revealed by examining the possible relationship between fetal complications were investigated.Öğe Ultrastructural Effects of the Propineb on Brain of Fetuses During Rat Pregnancy(Soc Chilena Anatomia, 2014) Ekinci, C.; Tahaoglu, A. E.; Yavuz, D.; Deveci, E.; Aktas, A.; Yilmaz, T.; Yumusak, O.Propineb is a fungicide with a propylene-bis-dithiocarbamate structure. Pregnant Wistar rats were exposed to 400 ppm propineb concentrations in 5 ml distilled water, 5 days per week until the end of pregnancy. The rats were treated with propineb for 16 days and the brains of litter rats were sacrificed at first day of birth after which their brains were collected. Ultrastructural examination of the brains of the fetuses and propineb-treated pregnant females revealed a variety of histopathological effects. We suggest that mitochondrial damage may be an effective factor for neuron necrosis. These results supported the proposal that the exposure to fungicides such as propineb and to other naturally occurring compounds which inhibit mitochondrial function, may contribute to Parkinson's disease development.
