Yazar "Yaman, Ferhan" seçeneğine göre listele
Listeleniyor 1 - 20 / 28
Sayfa Başına Sonuç
Sıralama seçenekleri
Öğe A Bimaxillary Orthognathic Surgery Approach to a Case of Long Face and Gummy Smile(Ankara Diş Hekimleri Odası, 2007) Erol, Behçet; Yaman, Ferhan; Atılgan, SerhatThe long face patients’ clinical characteristics are accompanied with gummy smileand/or anterior open bite. In these types ofpatients, both aesthetic and functionalreconstruction depend on a carefullyosteotomy planning.Upper lip position in relax, the relationbetween upper lip and incisors, face proportions are important criteria to decidewhether a patient has gummy smile and/oranterior open bite problems. Often verticalmaxillary excess is seen in these types ofdevelopmental malformation patients.Reducing the maxillary excess by Le Fort Iosteotomy and locating the mandible withrespect to maxilla by mandible osteotomyfor treatment provides satisfactory results.This study aims to present and discuss theaesthetic and functional results of a bimaxillary orthognathic surgical operation, conducted on a 21-year old female patient,who applied to our clinic with the complaints of aesthetic and chewing problemsÖğe Ağız içine sürmüş submandibular sialolitiazis: Olgu sunumu(2006) Ünlü, Gülten; Yaman, Ferhan; Atılgan, SerhatTükürük bezi taşları, tükürük bezi hastalıklarının genel bir sebebi olup herhangi bir tükürük bezinde ve her yaşta oluşabilmektedir. Bununla birlikte sialolit-lerin büyük bir kısmı (yaklaşık %85'i) submandibular bezlerde kendini gösterir. Sialolitiazis, tükürük bezi veya kanalını etkileyen ağrılı rekürrent şişlikler ile seyredebilen nispeten yaygın olmayan bir durumdur. Bu çalışmada ağız içine sürmüş submandibular sialolitiazisli olgu ve cerrahi tedavisi tartışılmıştır.Öğe A comparative evaluation of the effects of bevacizumab and 5-fluorouracil on wound healing in rat model(Drunpp-Sarajevo, 2012) Gunay, Ahmet; Atilgan, Serhat; Yesilova, Yavuz; Yaman, Ferhan; Ozgoz, Mehmet; Lacin, NihatPurpose: Our aim is to evaluate the use of combined bevacizumab with 5-Fluorouracil (5-FU) on post-operative scarring survival following experimental skin incision surgery in comparison to the agents alone. Material and methods: Skin incision surgery was performed on 28 female Spraque-Dawley rats. The rats were allocated to one of four treatments: 5-FU combined with Bevacizumab, 5FU alone, bevacizumab alone and phosphate buffered saline (PBS). A single subcutaneous injection was administered immediate postoperatively. Histological staining determined the presence of cutaneous fibrosis and mRNA expression of collagen I and fibronectin in the tissue was quantified. Results: Relative quantity of Colla1 mRNA transcript 5 fold increased in Group 1 (PBS) in comparison to control group. However, Colla1 level in Group 2 (5-FU) and 3 (bevacizumab) is decreased. The lowest level of Colla1 was detected in Group 4 (combination of 5-FU and bevacizumab). On the other hand, relative quantity of Fn1 is slightly elevated in Group 1 (PBS) and decreased in Group 2 (5-FU) and group 3 (bevacizumab) in comparison to control group. The lowest level of Fn 1 was detected in Group 4 (combination of 5-FU and bevacizumab). Conclusions: Bevacizumab in combination with 5-FU resulted in a greater anti-fibrotic effect compared to monotherapy with 5FU or bevacizumab alone, as evidenced by the attenuation in fibronectin and mature collagen I expression and deposition. (P<0.05) The results provide compelling evidence that combined bevacizumab and 5-FU offers superior anti-fibrotic effect over monotherapy. A synergistic effect is suggested to be present.Öğe Comparison of the Effects of Local and Systemic Zoledronic Acid Application on Mandibular Distraction Osteogenesis(Lippincott Williams & Wilkins, 2017) Dundar, Serkan; Artas, Gokhan; Acikan, Izzet; Yaman, Ferhan; Kirtay, Mustafa; Ozupek, Muhammed Fatih; Asutay, FatihBisphosphonates are antibone resorptive drugs that are used to prevent bone tissue resorption in several skeletal diseases. The aim of this study was to examine the effects of systemic and local applications of zoledronic acid (ZA) on newly regenerated bone in a model of experimental distraction osteogenesis (DO). To do this mandibular DO was applied to 30 adult female Sprague Dawley rats, which were randomly divided into 3 groups: control, DO only, systemic zoledronic acid (SZA), and local zoledronic acid (LZA). In the LZA group, the gap between the bone fragments was filled with a gelatin sponge soaked in 2mg of ZA and 0.1 mL of sterile saline. In the SZA group, a single dose of 0.1 mg/kg ZA was administered systemically. After the surgery, there was a 5-day latent waiting period and 10-day distraction phase. Following a 28-day consolidation period, the rats were euthanized and theirmandibles were collected. The distracted bone area was seen to be filled with newly regenerated bone tissue in all 3 groups, both histologically and histomorphometrically. In addition, amounts of new bone formation, osteoblast cella, osteoclast (OC) cells, osteopontin, and vascular endothelial growth factor in the SZA and LZA groups were found to be higher when compared with the controls. Furthermore, in the SZA group, new bone formation, osteoblast, OC, osteopontin, and vascular endothelial growth factor were detected in significant amounts compared with the LZA group. Osteoclast numbers did not differ in a statistically significant manner in the SZA group with respect to the LZA group. Based on the results of this study, systemic and local applications of ZA could increase the formation of new bone in patients of DO, and systemic application is a more effective method compared with local application.Öğe Dietary arginine silicate inositol complex increased bone healing: histologic and histomorphometric study(Dove Medical Press Ltd, 2016) Yaman, Ferhan; Acikan, Izzet; Dundar, Serkan; Simsek, Sercan; Gul, Mehmet; Ozercan, Ibrahim Hanifi; Komorowski, JamesBackground: Arginine silicate inositol complex (ASI; arginine 49.5%, silicon 8.2%, and inositol 25%) is a novel material that is a bioavailable source of silicon and arginine. ASI offers potential benefits for vascular and bone health. Objective: The aim of this study was to evaluate the potential effects of ASI complex on bone healing of critical-sized defects in rats. Methods: The rats were randomly assigned to two groups of 21 rats each. The control group was fed a standard diet for 12 weeks; after the first 8 weeks, a calvarial critical-sized defect was created, and the rats were sacrificed 7, 14, and 28 days later. The ASI group was fed a diet containing 1.81 g/kg of ASI for 12 weeks; after the first 8 weeks, a calvarial critical-sized defect was created, and the rats were sacrificed 7, 14, and 28 days later. The calvarial bones of all the rats were then harvested for evaluation. Results: Osteoblasts and osteoclasts were detected at higher levels in the ASI group compared with the control group at days 7, 14, and 28 of the calvarial defect (P<0.05). New bone formation was detected at higher levels in the ASI group compared with the controls at day 28 (P<0.05). However, new bone formation was not detected at days 7 and 14 in both the groups (P>0.05). Conclusion: ASI supplementation significantly improved bone tissue healing in rats with critical-sized defects. This study demonstrated that ASI can enhance bone repair and has potential as a therapeutic regimen in humans.Öğe Displaced lower third molar tooth into the submandibular space: Two case reports(Medknow Publications, 2014) Köse, İbrahim; Koparal, Mahmut; Güneş, Nedim; Atalay, Yusuf; Yaman, Ferhan; Atılgan, Serhat; Kaya, GürkanThe aim of this article is to emphasize that the accidental displacement of a lower third molar during extraction is a rare, but potentially serious complication. We present two case reports on a lower third molar tooth dislodged into the submandibular space following its removal from the sockets and the subsequent management of this rare complication. Differences in the direction of displacement, the size of fragment, delay in retrieval, and tissue reactions can all influence this potential serious complication and hence no one technique is uniformly applicable. Though a rare complication, clinicians must be aware of possible lower third molars dislodgement into tissue spaces and the necessity to initiate prompt and appropriate management.Öğe Effect of intracanal medication with calcium hydroxide and 1% chlorhexidine in endodontic retreatment cases with periapical lesions(Elsevier Singapore Pte Ltd, 2007) Ercan, Ertugrul; Dalli, Mehmet; Dulgergil, C. Turksel; Yaman, FerhanBackground/Purpose: Calcium hydroxide (Ca(OH)(2)) has been widely used as an intracanal medicament for endodontic retreatment, but very few studies used both Ca(OH)(2) and 1% chlorhexidine (CHX) as intracanal medicaments. The purpose of this study was to assess the in vivo effectiveness of a combination of Ca(OH)(2) and 1% CHX as intracanal medicaments in endodontic retreatment cases with periapical lesions. Methods: Previous cases of endodontically treated teeth with periapical pathosis in 70 patients (36 men and 34 women, age range 18-60 years) were included. Of these teeth, 59 had received root canal treatment and 11 had been subjected to previous apical surgery, indicating endodontic failure. Following the routine procedures, including canal reshaping and irrigation with 2% CHX, a canal medication material containing Ca(OH)(2) powder and a 1% CHX solution was placed into the root canals. Over a 6-week period, the intracanal medication was periodically changed until the teeth became asymptomatic. Patients were recalled at 3-month intervals for radiographic and clinical examination. Results: Our clinical and radiographic assessment of retreatment cases showed complete healing in 41 (64%) teeth, incomplete healing in 9 (14%) teeth, and failure in 14 (22%) teeth. For complete healing teeth, the healing time varied from 6 to 36 months. The size of the periapical lesions and previous surgical treatment had no influence on the prognosis. Conclusion: Our results suggest that a combination of Ca(OH)(2) and 1% CHX can be successfully used as intracanal medicament for disinfection in endodontic retreatment cases with periapical lesions.Öğe Effects of caffeic acid phenethyl ester on palatal mucosal defects and tooth extraction sockets(Dove Medical Press Ltd, 2014) Gunay, Ahmet; Arpag, Osman Fatih; Atilgan, Serhat; Yaman, Ferhan; Atalay, Yusuf; Acikan, IzzetAim: The purpose of this study was to evaluate the effects of caffeic acid phenethyl ester (CAPE) on palatal mucosal defects and tooth extraction sockets in an experimental model. Materials and methods: Forty-two male Sprague-Dawley rats with a mean age of 7 weeks and weighing 280-490 g were used in this study. The rats were randomly divided into two groups: group A (the control group, n=21) and group B (the experimental group, n=21). Under anesthesia with ketamine (8 mg/100 g, intraperitoneally), palatal mucosal defects were created and tooth extraction was performed in the rats in groups A and B. Group A received no treatment, whereas group B received CAPE. CAPE was injected daily (10 mu mol/kg, intraperitoneally). The rats were killed on days 7, 14, and 30 after the procedures. Palatal mucosa healing and changes in bone tissue and fibrous tissue were evaluated histopathologically. Result: Pairwise comparisons showed no statistically significant difference between days 7 and 14 in either group (P>0.05). At day 30, bone healing was significantly better in group B (CAPE) than in group A (control) (P<0.05). Fibrinogen levels at day 30 were significantly higher in group A (control) than in group B (CAPE) (P<0.05). Pairwise comparisons showed no statistically significant difference in palatal mucosa healing levels between days 7 and 14 in both groups (P>0.05). Conclusion: In conclusion, the findings of this study suggest that CAPE can significantly improve tooth socket healing.Öğe The effects of high-fat diet on implant osseointegration: an experimental study(Korean Acad Oral & Maxillofacial Surgery, 2016) Dundar, Serkan; Yaman, Ferhan; Ozupek, Muhammed Fatih; Saybak, Arif; Gul, Mehmet; Asutay, Fatih; Kirtay, MustafaObjectives: In this study, we investigated whether a high-fat diet (HFD) affected the bone implant connection (BIC) in peri-implant bone. Materials and Methods: Four male rabbits were used in this study. Dental implant surgery was introduced into each tibia, and four implants were integrated into each animal. In both the normal diet (ND) group (n=2) and HFD group (n=2), 8 implants were integrated, for a total of 16 integrated implants. The animals continued with their respective diets for 12 weeks post-surgery. Afterward, the rabbits were sacrificed, and the BIC was assessed histomorphometrically. Results: Histologic and histomorphometric analyses demonstrated that BIC was not impaired in the HFD group compared to the ND group. Conclusion: Within the limitations of this study, we found that HFD did not decrease the BIC in rabbit tibias.Öğe Effects of Local and Systemic Zoledronic Acid Application on Titanium Implant Osseointegration: An Experimental Study Conducted on Two Surface Types(Lippincott Williams & Wilkins, 2017) Dundar, Serkan; Yaman, Ferhan; Gecor, Orhan; Cakmak, Omer; Kirtay, Mustafa; Yildirim, Tuba Talo; Karaman, TahirThe aim of this study was to evaluate the effects of local and systemic zoledronic acid (ZA) applications on titaniumoksit ceramic blasted (TiO-CB)- and sandblasted large acid-grit (SLA)-surfaced titanium implant osseointegration. Twelve New Zealand White rabbits were used in the study, divided into 6 groups: the TiO-CB (TiO-CB-CNT) (n = 2) and SLA (SLA-CNT) (n = 2) control groups in which TiO-CB- and SLA-surfaced titanium implants were surgically inserted into rabbit tibias but no treatment was applied; the TiO-CB (TiO-CB-LZA) (n = 2) and SLA (SLA-LZA) (n = 2) local ZA groups in which 1 mL of normal saline solution containing 2 mg of ZA was injected into sockets and after this the implants were integrated; and the TiO-CB (TiO-CB-SZA) (n = 2) and SLA (SLA-SZA) (n = 2) systemic ZA groups in which a single infusion of 0.1 mg/kg of ZA was administered during surgical implant insertion. Following a period of osseointegration, bone implant contact (BIC) was recorded as a proportion of the total implant surface length in direct contact with the bone. Results of this study indicate that BIC was greater in the systemic ZA application groups than in the local ZA application groups, and BIC was greater in the local ZA groups than in the controls. Statistically significant differences in BIC were not detected between the TiO-CB- and SLA-surfaced implants in all the groups. Furthermore, this study did not reveal significant differences between the 2 types of surfaces due to similar average roughness values. Overall, systemic ZA application was found to be more effective in increasing BIC than local ZA application based on the results obtained by testing 2 implant surfaces.Öğe Effects of Sildenafil on Dental Pulp: Immunohistochemical and Ultrastructural Evaluation(Soc Chilena Anatomia, 2016) Soker, Sevda; Deveci, Engin; Yaman, Ferhan; Atilgan, Serhat; Ipek, Fikret; Uysal, IbrahimSildenafil is a strong peripheral vasodilator and is used to treat cardiovascular and neurosurgery. The purpose of this study was to investigate the immunohistochemical and ultrastructural effects of sildenafil on dental pulp of rats. The study was performed with adult female Wistar-Albino rats. Control group (n=7) were fed on standard laboratory diet until surgery. The study group (n=7) were administered sildenafil orally with orogastric tube 10 mg.kg(-1) once a day for 30 days. Each rat was anesthetized and incisor teeth were removed. This study examined the immunohistochemical and ultrastructural effects of sildenafil on the dental pulp in rats. The relaxation from the vessel, endothelial cell hyperplasia, moderate degeneration of collagen fibers were observed to cause degenerative changes in odontoblast with sildenafil. In the pulp tissue long-term use sildenafil is thought to cause degeneration and new vessel formation.Öğe Effects of Sildenafil on Dental Tissue(Medwell Online, 2011) Yaman, Ferhan; Soker, Sevda; Atilgan, Serhat; Erol, Behcet; Alp, Harun; Agacayak, Serkan Kamil; Gunay, AhmetTo investigate the effects of Sildenafil on dental tissue. The study was performed with adult female Wistar-Albino rats. Control group (n = 7) were fed on standard laboratory diet until surgery. The study group (n = 7) were administered Sildenafil orally with orogastric tube 10 mg kg(-1) once a day for 30 days. Each rat was anesthetized and mandibular bone with incisor teeth and soft tissue were removed. Dental pulp, dentin, periodental ligament, periodental soft tissue and bone were examined histologically. Neovascularization on the dental pulp and gingiva were significantly higher in the study group. Sildenafil can be used as a supporting factor in dental tissue healing.Öğe Effects of Systemic Zoledronic Acid Administration on Osseointegration of Hydroxyapatite-Coated and Resorbable Blast Material Surface Implants in Rabbit Models(Quintessence Publishing Co Inc, 2012) Yaman, Ferhan; Agacayak, Serkan; Atilgan, Serhat; Benlidayi, Emre; Ucan, Musa Can; Erol, Behcet; Kaya, BeyzaPurpose: It is unknown whether zoledronic acid (ZA) interferes with initial bone healing at implant sites. The goal of this study was to examine the effects of systemic zoledronic acid administration on osseintegration of hydroxyapatite (HA)-coated and resorbable blast material surface (RBM) implants in rabbit models. Materials and Methods: Twenty-eight male New Zealand rabbits (aged 6 to 12 months) were used in this study. Rabbits were randomly assigned to four groups. In group A, HA-coated implants were placed in the right tibia of seven rabbits. In group B, RBM-surface implants were placed in the right tibia of seven rabbits. In group C, HA-coated implants were placed in seven rabbits with intravenous (IV) administration of ZA. Finally, in group D. ROM-surface implants were placed in seven rabbits with IV administration of ZA. For groups C and D, IV zoledronic acid (0.1 mg/kg) was performed monthly during the entire osseointegration period. All of the rabbits were sacrificed 12 weeks after the implantation, and tibial specimens were harvested. Histomorphometric bone-to-implant contact (BIC) analysis and the data were statistically analyzed. Results: The highest BIC percentage was detected in group D, with a mean value of 56.73% +/- 1.85%, as compared with 45.80% +/- 3.77% in group C, 35.11% +/- 0.76% in group B, and 3114% +/- 1.04% in group A. Conclusions: Histomorphometric analyses showed significant improvement in the osseointegration of implants in the RBM-surface ZA group compared with the HA-coated ZA group. The results of this study suggest that systemic ZA administration may improve osseointegration of titanium implants in bone. INT J ORAL MAXILLOFAC IMPLANTS 2012;27:1443-1447Öğe Evaluation of Effects of Topical Melatonin Application on Osseointegration of Dental Implant: An Experimental Study(Allen Press Inc, 2016) Dundar, Serkan; Yaman, Ferhan; Saybak, Arif; Ozupek, M. Fatih; Toy, Vesile Elif; Gul, Mehmet; Ozercan, I. HanifiThe aim of the present study was to evaluate the effect of local melatonin application during surgery on bone implant connection (BIC) in rabbit tibiae. Six 0.8- to 1-year-old male New Zealand rabbits were divided into 3 groups: (1) a control group (CG) in which rabbits were not treated with additive materials and only implant integration was executed; (2) a melatonin dose 1 (MLT D-1) group in which rabbits were treated with 1.2 mg of melatonin locally before implant placement into the rabbits' tibiae; and (3) a melatonin dose 2 (MLT D-2) group in which rabbits were treated with 3 mg melatonin locally before implant placement into the rabbits' tibiae. Four weeks after the procedure, the rabbits were euthanized; their tibiae were dissected from muscles and soft tissues, fixed with formaldehyde, and later embedded in methacrylate. Histologic and histomorphometric analyses were then performed under light microscopy. Following this, BIC was detected histomorphometrically, and P<.05 was considered statistically significant. Results showed that the highest BIC percentage was detected in MLT D-2, with a mean value of 39.46% +/- 0.78, as compared with a mean value of 33.89% +/- 0.92 in group MLT D-1 and 27.42% +/- 0.89 in CG. Similarly, the mean BIC percentage of the MLT D-2 group was the highest among the three, with the mean BIC percentage of the MLT D-1 still registering as higher than CG. Within the limitations of this rabbit study, it appears that local melatonin application during implant surgery may improve BIC.Öğe Evaluation of Mandibular Fractures in Children during Five years' in a Dental School(Drunpp-Sarajevo, 2012) Yaman, Ferhan; Atilgan, Serhat; Erol, Behcet; Ucan, Musa Can; Yilmaz, Utku Nezih; Agacayak, Serkan Kamil; Gunes, NedimMandibular fractures are rarely encountered among the pediatric population, and when they do present, their clinical features differ from those in adults. This retrospective study looked at the age, sex, type and cause of fracture, treatment method and associated injuries and complications in 260 cases of mandibular fracture in children under age 16. Among the most significant findings: Fracture incidence had a 3:5 male:female ratio; 52% of all mandibular fractures involved condyle/subcondyle fractures and 50.7% involved symphysis/parasymphysis fractures; the most common treatment method was intermaxillary fixation; in no cases were severe complications observed during the healing period.Öğe Finite element analysis of the stress distributions in peri-implant bone in modified and standard-threaded dental implants(Taylor & Francis Ltd, 2016) Dundar, Serkan; Topkaya, Tolga; Solmaz, Murat Yavuz; Yaman, Ferhan; Atalay, Yusuf; Saybak, Arif; Asutay, FatihThe aim of this study was to examine the stress distributions with three different loads in two different geometric and threaded types of dental implants by finite element analysis. For this purpose, two different implant models, Nobel Replace and Nobel Active (Nobel Biocare, Zurich, Switzerland), which are currently used in clinical cases, were constructed by using ANSYS Workbench 12.1. The stress distributions on components of the implant system under three different static loadings were analysed for the two models. The maximum stress values that occurred in all components were observed in F-III (300 N). The maximum stress values occurred in F-III (300 N) when the Nobel Replace implant is used, whereas the lowest ones, in the case of F-I (150 N) loading in the Nobel Active implant. In all models, the maximum tensions were observed to be in the neck region of the implants. Increasing the connection between the implant and the bone surface may allow more uniform distribution of the forces of the dental implant and may protect the bone around the implant. Thus, the implant could remain in the mouth for longer periods. Variable-thread tapered implants can increase the implant and bone contact.Öğe Gecikmiş bilateral mandibular kondil fraktürünün tedavisi: Olgu raporu sunumu(2008) Ünlü, Gülten; Atılgan, Serhat; Yaman, FerhanÇocuklarda kondu fraktürlerinin tedavisi özellik gösterir ve bu tür fraktürlerin uygun tedavisi uzun zamandan beri tartışma konusu olmuştur. Tedavi alternatifleri olarak; intermaksil-ler fiksasyon (IMF) ile birlikte intra-osseoz fiksasyon, IMF ile birlikte immobilizasyon, erken hareket ve normal yemek yeme alışkanlığını vurgulayan immobilizasyonsuz tedavi seçenekleri sıralanabilir, "primum nü nocere " prensibi ile splintleme yoluyla konservatif non-invaziv tedaviyi, fraktürün cerrahi tedavisine tercih ettiğimiz bilateral kondu fraktürü olan olgumuzun tedavi şeklini ve sonuçlarını tartışmayı amaçladık.Öğe Guided bone regeneration with local zoledronic acid and titanium barrier: An experimental study(Spandidos Publ Ltd, 2016) Dundar, Serkan; Ozgur, Cem; Yaman, Ferhan; Cakmak, Omer; Saybak, Arif; Ozercan, Ibrahim Hanifi; Alan, HilalThe aim of this study was to evaluate the effects on new bone formation of autogenous blood alone or in combination with zoledronic acid (ZA), a -tricalcium phosphate (-TCP) graft or ZA plus a -TCP graft placed under titanium barriers. For this purpose, eight adult male New Zealand white rabbits were used in the study, each with four titanium barriers fixed around four sets of nine holes drilled in the calvarial bones. The study included four groups, each containing 2 rabbits. In the autogenous blood (AB group), only autogeneous blood was placed under the titanium barriers. The three experimental groups were the AB+ZA group, with autogenous blood plus ZA, the AB+-TCP group, with autogeneous blood plus a -TCP graft, and the AB+-TCP+ZA group, with autogeneous blood plus a -TCP graft and ZA mixture under the titanium barriers. The animals were sacrificed after 3 months. The amounts of new bone formation identified histomorphometrically were found to be higher after 3 months than at the time of surgery in all groups. The differences between the groups were examined with histomorphometric analysis, and statistically significant differences were identified at the end of the 3 months. The bone formation rate in the AB+-TCP+ZA group was determined to be significantly higher than that in the other groups (P<0.05). In the AB+ZA and AB+-TCP groups, the bone formation rate was determined to be significantly higher than that in the AB group (P<0.05). No statistically significant difference in bone formation rate was observed between the AB+-TCP and AB+ZA groups. Local ZA used with autogeneous blood and/or graft material appears to be a more effective method than the use of autogeneous blood or graft alone in bone augmentation executed with a titanium barrier.Öğe Guided bone regeneration with polyethylene membrane, zoledronic acid and hydroxiapatide bone graft in peri-implant bone defect: An experimental study(Allied Acad, 2017) Yaman, Ferhan; Dundar, Serkan; Cakmak, Omer; Saybak, Arif; Kirtay, Mustafa; Kaya, Beyza; Kom, MustafaThis study aimed to determine the guided bone regeneration (GBR) capacity of peri-implant bone defect treatment, either with only a hydroxyapatite bone graft or with a hydroxyapatite bone graft mixed with zoledronic acid (ZA) and employing polyethylene glycol (PEG) barrier membranes. In this study, four male New Zealand rabbits were used. First, the rabbits were randomly divided into two groups, the hydroxyapatite graft group (HA) (n=2) and the HA graft + zoledronic acid group (HA+ZA) (n=2). For the HA group, peri-implant GBR was performed with only an HA bone graft, and a resorbable PEG barrier membrane was placed over each surgical defect to cover the peri-implant bone defects. For the HA+ZA group, peri-implant GBR was performed with an HA bone graft that had previously been mixed with ZA. A resorbable PEG barrier membrane was placed over each surgical defect to cover the peri-implant bone defects. Experiments were performed using a standardised peri-implant bone tissue defect model in rabbit tibia for 60 days. Circumferential defects were surgically induced around the dental implants on the tibias of four rabbits. Sixty days after the surgical procedures, the rabbits were sacrificed, and their tibias with the graft sites were harvested for histologic evaluation. In the HA+ZA group, significantly more new bone formation was detected as compared with the HA group (P<0.05). Within the limitations of this study, locally administered ZA with an HA synthetic graft and PEG membrane was a more effective method as compared to using only a graft in a peri-implant GBR procedure. Additionally, a PEG membrane should be useful in GBR as a barrier membrane. Further studies are needed to confirm these results.Öğe Malpractise in a child with mandibular fracture: A case report(2006) Yaman, Ferhan; Atılgan, Serhat; Erol, BehçetThis study aims to discuss malpractise case report and treatment principles for pediatric mandibular fractures. In our study an 11-year-old girl was reffered to our clinic with facial asymmetry who were treated with titan mech for mandibular fracture when she was 4 years old. Titan mech was to be left in her mouth for seven years. Under local anesthesia titan mech and screws were removed by intra-oral approach. Furthermore distraction osteogenesis was planned for the treatment of facial asymmetry. As a result of this paper we recommend that screws and plates should be removed as soon as healing period is over and especially in pediatric cases, doctors must have a greater responsibility about therapy period.
