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Öğe The accuracy and validity of a weekly point-prevalence survey for evaluating the trend of hospital-acquired infections in a university hospital in Turkey(Elsevier Sci Ltd, 2011) Ustun, Cemal; Hosoglu, Salih; Geyik, Mehmet Faruk; Parlak, Zafer; Ayaz, CelalObjective: To evaluate the validity of a weekly point-prevalence survey (WPS) by comparing it with a prospective-active incidence survey (PIS). Methods: WPS and PIS were conducted at a tertiary referral hospital between January and December 2006. Each Wednesday, an infection control team reviewed all clinical records of patients with hospital-acquired infections (HAIs) by WPS. Routine PIS was conducted with daily visits by the same team. The Rhame and Sudderth formula was used for converting the data between WPS and PIS. Results: During the study period, 1287 HAIs were detected in 37 466 patients by WPS. The mean observed prevalence and calculated prevalence were 5.42% and 5.45%, respectively. The reanimation intensive care unit (ICU) (49.4%) and burns unit (27.6%) had the highest prevalence rates. Pneumonia (0.94%) and urinary tract infections (0.37%) were the most frequent infections. Overall 602 HAIs were detected in 545 patients by PIS. The mean observed incidence and calculated incidence were 2.42/1000-admissions and 2.41/1000-admissions, respectively. The Critical care ICU (37.0/1000-admissions) and burns unit (24.8/1000-admissions) had the highest incidences of HAI. Pneumonia (0.64/1000-admissions) and urinary tract infections (0.37/1000-admissions) were the most frequent infections. Conclusions: This study confirms a close relationship between prevalence and incidence data. WPS may be a useful method for following HAIs when PIS cannot be performed. (C) 2011 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.Öğe Acute Generalized Exanthematous Pustulosis Associated with Tigecycline(Korean Dermatological Assoc, 2014) Ozturk, Savas; Ustun, Cemal; Pehlivan, Sultan; Ucak, HaydarAcute generalized exanthematous pustulosis (AGEP) is a severe and rare eruption that develops mostly from factors related to drugs. It is characterized by a fever and a pustular eruption on the erythematous skin with an acute onset and without follicular localization. Etiopathogenesis has not yet been fully explained. Although it is similar to pustular psoriasis, its clinical, historical and histopathological characteristics are different. In this article, we present a case of AGEP associated with tigecycline that developed in a patient followed up in the intensive care unit for three months with an intra-abdominal injury after a trauma and Acinetobacter baumannii infection.Öğe A case of brucellar spondylodiscitis involving the cervical spine(Ios Press, 2009) Nas, Kemal; Bukte, Yasar; Ustun, Cemal; Cevik, Remzi; Geyik, Mehmet Faruk; Batmaz, IbrahimWe have presented a patient of 71-year-age with brucellar spondylodiscitis, involving the cervical spine, especially the C3-C4 segment. The patient had painful percussion of the cervical spine and passive mobilization of the neck, decreased range of motion, and cervical paravertebral tenderness; but no abnormalities observed on neurological examination. Wright agglutination test for brucella was positive at 1/320. Cervical localization for brucellar spondylodiscitis is an unusual case and should be detected and treated as early as possible. In endemic regions, spinal involvement of brucellosis should be considered in cases with fever, neck and low back pain.Öğe The efficacy of dexamethasone treatment in massive enteric bleeding in typhoid fever(Sage Publications Inc, 2009) Hosoglu, Salih; Ustun, Cemal; Geyik, Mehmet Faruk[Abstract Not Available]Öğe Epidemiology of Cases with Rabies-Suspected Animal Contact and the Evaluation of Post Exposure Prophylaxis(Ortadogu Ad Pres & Publ Co, 2012) Gulacti, Umut; Ustun, Cemal; Gurger, Mehtap; Sahan, Mustafa; Satici, OmerObjective: This study aims to evaluate the epidemiology of cases with rabies-suspected animal contact (RSAC) and the appropriateness of rabies post-exposure prophylaxis (RPEP). Material and Methods: This retrospective study was carried out at the emergency departments of two general hospitals between January 2010 and August 2011. The management charts of cases with RSAC who were admitted to the emergency room were reviewed. Statistical analysis of data was done using SPSS for Windows (version 16.0). Results: Of 616 study cases, 464 (75.3%) were male and 152 (24.7%) were female. Cases in the subgroup aged 6-15 years had the highest risk for RSAC. Four hundred and thirty one (70%) cases lived in an urban area, and most cases had presented in the spring (36.9%) and summer (31.3%). Dogs were the most common animal (66.9%) causing RSAC with statistical significance (p=0.001). Bite was the most common way of contact with 454(73.7%) cases reaching statistical significance (p=0.001). Of 616 animals responsible for RSAC, 336 (54.6%) had no owner, while the others (280, 45.4%) had owners. RPEP was considered inappropriate in 529 (85.9%) cases according to the Rabies Prevention and Control Guidelines of the Ministry of Health, with statistical significance (p=0.001). The most frequent inappropriate procedure was the lack of rabies immunoglobulin administration in 303 (57.3%) cases. Conclusion: RSAC is an important public health problem in our region. There are some problems in the application of Rabies Prevention and Control Guidelines of the Ministry of Health and this guideline should be updated. Routine training of healthcare workers may be an effective solution against rabies.Öğe Orf. A case of viral skin disease(Aves, 2007) Ustun, Cemal; Ayaz, Celal; Geyik, Mehmet Faruk; Celen, Mustafa Kemal; Hosoglu, Salih37-year-old male patient, who had several vesicular and pustular lesions on his hands, was admitted to our outpatient clinic. He was hospitalised with the diagnosis of cutaneous anthrax. Empirical antibiotic was begun and cutaneous biopsy was performed. A viral skin infection related to orf virus from the Poxviridae family was detected by the histopathological examination of the biopsy material. Thereby the subject of orf was studied.Öğe Risk factors for occupational brucellosis among veterinary personnel in Turkey(Elsevier Science Bv, 2014) Kutlu, Murat; Ergonul, Onder; Sayin-Kutlu, Selda; Guven, Tumer; Ustun, Cemal; Alp-Cavus, Sema; Ozturk, Serife BaronVeterinarians and veterinary technicians are at risk for occupational brucellosis. We described the risk factors of occupational brucellosis among veterinary personnel in Turkey. A multicenter retrospective survey was performed among veterinary personnel who were actively working in the field. Of 712 veterinary personnel, 84(11.8%) had occupational brucellosis. The median number of years since graduation was 7 (interquartile ranges [IQR], 4-11) years in the occupational brucellosis group, whereas this number was 9 (IQR, 4-16) years in the non-brucellosis group (p < 0.001). In multivariable analysis, working in the private sector (odds ratio [OR], 2.8; 95% confidence interval [95% CI], 1.55-5.28, p = 0.001), being male (OR, 4.5; 95% CI, 1.05-18.84, p = 0.041), number of performed deliveries (OR, 1.01; 95% CI, 1.002-1.02, p = 0.014), and injury during Brucella vaccine administration (OR, 5.4; 95% CI, 3.16-9.3, p < 0.001) were found to be risk factors for occupational brucellosis. We suggest that all veterinary personnel should be trained on brucellosis and the importance of using personal protective equipment in order to avoid this infection. (C) 2014 Elsevier B.V. All rights reserved.Öğe The Role of Trace Elements in Helicobacter Pylori Infected Patients(Kuwait Medical Assoc, 2011) Bozkurt, Fatma; Gulsun, Serda; Ustun, Cemal; Geyik, Mehmet Faruk; Hosoglu, SalihObjective: To evaluate the effect of trace elements in patients with Helicobacter pylori associated chronic gastritis Design: Prospective study Settings: Clinical services of the clinical microbiology and infectious diseases and gastroenterology clinics at Dicle University, Turkey Subjects:A total of 92 patients with variable severity of chronic gastritis (45 Helicobacter pylori positive and 47 Helicobacter pylori negative gastritis) and 90 age and sex matched healthy subjects were included in the study conducted between October 2006 and November 2008. Intervention: Histopathologic examination, culture of Helicobacter pylori and urease tests were performed for each patient. The atomic absorption spectrophotometer was used in the measurement of trace elements in the serum. Main Outcome Measures: Serum copper and zinc levels were significantly elevated in patients with Helicobacter pylori associated gastritis compared to Helicobacter pylori negative gastritis and healthy controls (p < 0.0001). Serum copper, zinc and Cu / Zn levels in patients with Helicobacter pylori negative chronic gastritis was not significantly different from the serum levels in healthy controls (p > 0.05). Conclusions: Our results suggest a relationship between Helicobacter pylori associated chronic gastritis and the elevation of trace element levels in serum. This study confirms that the elevation of trace element levels in serum (Cu and Zn levels) will be helpful in the diagnosis of Helicobacter pylori associated chronic gastritis in the abscence of invasive procedures, and is useful in predicting the severity of infection in patients with chronic gastritis.Öğe The role of trace elements in wagner classified diabetic patients(Academic Journals, 2011) Bozkurt, Fatma; Gulsun, Serda; Ustun, Cemal; Geyik, M. Faruk; Tegin, Ibrahim; Satici, OmerWagner's classification is the most widely used grading system in diabetic foot infections. The aim of this study was to evaluate the role of the trace elements in diabetic foot infected patients graded with Wagner's classification. This prospective study was carried out on 50 diabetic patients with variable severity of foot infections and 50 age and sex matched healthy subjects in Dicle University, Turkey, between October 2006 and November 2008. Diabetic foot infections were graded according to Wagner classification and deep tissue cultures were performed from all diabetic foot infected patients. The atomic absorption spectrophotometer was used in the measurement of trace elements in the serum. serum zinc and copper levels were significantly elevated in patients with Wagner 3 and 4 compared to Wagner 2 and 1 graded patients and healthy controls. Also Wagner 1 and 2 graded patients had higher serum zinc levels compared to healthy controls (p < 0.001). This study confirms that trace elements may be used as a leading sign to determine the severity of infections in diabetic foot wounds and may be used to predict outcome of diabetic foot infections.Öğe The surveillance of device-related health care-associated infections in neurosurgical intensive care unit(Aves, 2008) Ustun, Cemal; Ayaz, Celal; Guzel, Aslan; Celen, Mustafa Kemal; Tekin, RecepThe invasive device utilization ratios and device-related health care-associated infections (DRIs) rate were analyzed in 2006, at neurosurgical intensive care unit (NICU) in Dicle University. Data were recorded to a standard form daily. The patients were defined by using Centers for Diseases Control and Prevention definitions. NICU has six beds, where 134 patients were hospitalized, in 2006. Of the patients 89 (66%) were male, 45 (34%) were female. Fourteen nosocomial infection (NI) attacks were detected in 13 patients. NI rate was detected as 10.4%. Six of these NIs were DRIs (43%). DRIs rate for mechanical ventilator and urinary catheter were found as 14.5 and 1.1, respectively. Central venous catheter-related bacteremia was not detected. ICUs are areas of high risk for NIs, associated with the invasive procedures frequently performed; and areas where patients in bad general condition were hospitalized in. A close monitorization of the patients, in terms of DRIs, may decrease the DRIs rate.
