Yazar "Ulgen, Mehmet Siddik" seçeneğine göre listele

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    Atrial Fibrillation in Turkey: Epidemiologic Registry (AFTER) study design
    (Turkish Soc Cardiology, 2013) Ertas, Faruk; Kaya, Hasan; Yuksel, Murat; Soydinc, Mehmet Serdar; Alan, Sait; Ulgen, Mehmet Siddik
    Objective: Atrial fibrillation (AF) is an important health problem in Turkey. However, no prospective, multicenter, large trial reflecting national data has been published so far. Therefore, the aim of this study was to follow, analyze and evaluate patients with AF in a large multicenter nation-wide trial. Methods: Two thousand three hundred consecutive patients with AF in their electrocardiogram, reflecting all the population of seven geographical regions of Turkey will be included in the study. The patients will be followed up for two years and death, transient ischemic attack, stroke, systemic thromboembolism, major bleeding, hospitalization will be recorded as the primary end-point. Results: Will be available at the end of the study; preliminary results will be due December 2012. Conclusion: General risk profile of patients with AF, frequency of anticoagulation, frequency of effective treatment and risks of bleeding will be evaluated according to the current guidelines. Major adverse events and their independent predictors will be determined.
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    The effect of ACE gene polymorphisms on Doppler blood flow parameters of carotid and brachial arteries in patients with myocardial infarction
    (Sage Publications Inc, 2006) Bilici, Aslan; Ulgen, Mehmet Siddik; Nazaroglu, Hasan; Ozturk, Onder; Ekici, Faysal; Akgul, Cihan; Alan, Bircan
    The authors investigated the relationship between the angiotensin-converting enzyme (ACE) insertion/deletion (I/D) polymorphism and the blood flow characteristics of common carotid (CCA) and brachial arteries (BA) by color Doppler ultrasound (CDUS) in patients with acute anterior myocardial infarction (AAMI). Sixty four patients (11 women and 53 men), aged 25 to 77 years, with AAMI were studied. The ACE genotypes were established. Peak-systolic (PSV) and end-diastolic velocity (EDV) of right and left CCA, PSV of right BA, and intimal-medial thickness (IMT) of both CCAs were measured by CDUS. All results were evaluated statistically. The ACE genotypes were distributed as follows: 43.8% DD, 43.8% ID, and 12.5% II. PSVs of BA and both CCAs were lower in patients with DD and ID than with 11 (p < 0.05). EDVs of both CCAs were also lower in the same groups, but statistically not significant (p > 0.05). IMTs of both CCAs did not differ among patients with various ACE genotypes (p > 0.05). These results suggest that ACE I/D polymorphism influences Doppler blood flow parameters of both BA and CCA, but does not affect IMT of CCA.
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    A second percutaneous closure due to residual mitral paravalvular leak and successful treatment of device embolization
    (Turkish Soc Cardiology, 2013) Kaya, Hasan; Ertas, Faruk; Ulgen, Mehmet Siddik; Goktekin, Omer
    Paravalvular leak (PVL) is a common complication after surgical valve replacement. Most PVLs remain clinically silent; however, some may require reoperation due to symptomatic PVL. Surgical closure of PVL remains the most common therapy for these defects; however, redo surgery has some disadvantages, including a high recurrence rate as well as high morbidity and mortality rates. Percutaneous closure of PVLs has emerged as an alternative to surgical closure. A 42-yearold male patient underwent a second percutaneous closure due to residual mitral paravalvular leak. During the procedure, the closure device embolized in the descending aorta. The device was captured with a snare and successfully retrieved, and then PVL was successfully occluded with another device.