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  • Küçük Resim
    Öğe
    Dynamic contrast-enhanced mammography and breast MRI in the diagnosis of breast cancer and detection of tumor size
    (Turkiye Klinikleri, 2024) Tekinhatun, Muhammed; Sabir, Nuran; Erdem, Ergün; Yılmaz, Sevda; Ufuk, Furkan
    Background/aim: The aim of this study is to evaluate the performance of contrast-enhanced mammography (CEM) and dynamic breast MRI techniques for diagnosing breast lesions, assess the diagnostic accuracy of CEM’s using histopathological findings, and compare lesion size measurements obtained from both methods with pathological size. Materials and methods: This prospective study included 120 lesions, of which 70 were malignant, in 104 patients who underwent CEM and MRI within a week. Two radiologists independently evaluated the MR and CEM images in separate sessions, using the BI-RADS classification system. Additionally, the maximum sizes of lesion were measured. Diagnostic accuracy parameters and the receiver operating characteristics (ROC) curves were constructed for the two modalities. The correlation between the maximum diameter of breast lesions observed in MRI, CEM, and pathology was analyzed. Results: The overall diagnostic values for MRI were as follows: sensitivity 97.1%, specificity 60%, positive predictive value (PPV) 77.3%, negative predictive value (NPV) 93.8%, and accuracy 81.7%. Correspondingly, for CEM, the sensitivity, accuracy, specificity, PPV, and NPV were 97.14%, 81.67%, 60%, 77.27%, and 93.75%, respectively. The ROC analysis of CEM revealed an area under the curve (AUC) of 0.907 for observer 1 and 0.857 for observer 2, whereas MRI exhibited an AUC of 0.910 for observer 1 and 0.914 for observer 2. Notably, CEM showed the highest correlation with pathological lesion size (r = 0.660 for observer 1 and r = 0.693 for observer 2, p < 0.001 for both). Conclusion: CEM can be used with high sensitivity and similar diagnostic performance comparable to MRI for diagnosing breast cancer. CEM proves to be a successful diagnostic method for precisely determining tumor size.
  • [ X ]
    Öğe
    İnterstisyel Akciğer Anormallikleri: Özellikleri ve Akciğer Kanseri Birlikteliği
    (2024) Ufuk, Furkan; Tekinhatun, Muhammet
    İnterstisyel akciğer anormallikleri (İAA), farklı bir patolojinin araştırılmasına yönelik elde olunan bilgisa- yarlı tomografi (BT) incelemeleri sırasında saptanan interstisyel anormalliklere işaret eder ve potansiyel olarak interstisyel akciğer hastalığı (İAH) ile ilişkilidir. İAA, özellikle akciğer kanserine yönelik elde edilen toraks BT taramalarının yaygınlaşması ve tanısal BT kullanımının artması (örneğin; koroner BT anjiyografi, metastaz araştırılması gibi) nedeniyle giderek daha sık olarak rapor edilmektedir. Sigara ve ileri yaş, İAA için önemli risk faktörleridir. İAA’nın varlığı, solunum fonksiyonlarında bozulma, İAH’ye radyolojik prog- resyon ve tüm nedenlere bağlı mortalitede artışla ilişkilidir. Ayrıca İAA varlığı, akciğer kanserli olgularda kötü prognoz göstergesidir. Bu nedenle radyologların İAA’nın farkında olması ve raporlaması büyük önem taşımaktadır. Bu derleme, İAA’nın radyolojik bulgularını, klinik önemini ve akciğer kanseri ile olan birlikte- liğini gözden geçirmeyi amaçlamaktadır.
  • Küçük Resim
    Öğe
    Pericardial rupture of mediastinal mature cystic teratoma: An unusual cause of pediatric acute chest pain
    (John Wiley and Sons Inc., 2023) Tekinhatun, Muhammed; Ufuk, Furkan; Yılmaz, Münevver; Gürses, Dolunay; Kış, Argün; Öztürk, Gökhan
    Apreviouslyhealthy12‐year‐old girl presented to the emergency departmentwith severe chest pain and dyspnea that woke her from sleep. She had short‐termsyncope just before the emergency admission. On physical examination,respiratory rate was 26 breaths per minute while resting, and blood pressurewas 92/56 mmHg. Other physical examination findings were insignificant. Shehad no past medical history, and her family history was unremarkable. Laboratorytest results showed elevated C‐reactive protein (27 mg/L; reference range:<5 mg/L) and white blood cell count (13.7 K/μL; reference range: 4–12 K/μL).Other laboratory test results were within normal limits, including troponinT value(3 ng/L; reference range: 3–14 ng/L). An electrocardiogram showed 1 mmST‐segment elevation in bipolar (D1 and D2) limb leads, and augmented vectorfoot leads, and echocardiography revealed a complicated pericardial effusion anda suspicious mass adjacent to the left ventricle.