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Öğe A case of orf (ecthyma contagiosum) with multiple lesions(Pakistan Medical Assoc, 2013) Turan, Enver; Yesilova, Yavuz; Ucmak, DeryaOrf, also known as ecthyma contagiosum or contagious pustular dermatitis, is a viral zoonotic disease resulting from the direct or indirect contact of damaged skin with infected animals. The causative microorganism is the orf virus, an epitheliotropic DNA virus from the Parapoxvirus group, which generally infects sheep, goats, and various other domestic and wild ovine animals. A male patient presented to our outpatient clinic with multiple nodular lesions on his right wrist after incurring an injury during ovine slaughter. Diagnoses other than ecthyma contagiosum were eliminated by punch biopsy. Orf generally manifests as solitary lesions on hands and fingers, but it may rarely present as multiple nodular lesions. Here we present the case of a 42-year-old man diagnosed with orf based on clinical and histopathological findings.Öğe Determination of dermatology life quality index, and serum C-reactive protein and plasma interleukin-6 levels in patients with chronic urticaria(Termedia Publishing House Ltd, 2013) Ucmak, Derya; Akkurt, Meltem; Toprak, Gulten; Yesilova, Yavuz; Turan, Enver; Yildiz, IsmailIntroduction: C-reactive protein (CRP) and interleukin-6 (IL-6), which is one of its most important simulators, were determined in great amounts in the sera of patients with chronic urticaria (CU). Aim: To determine the levels of IL-6 in patients with urticaria, and evaluate its relationship with urticaria activity scores and Dermatology Life Quality Index (DLQI). Material and methods: Fifty-three patients with CU were included in the study successively by determining their urticaria activity scores (0-3) and DLQI (0-5). The CRP and IL-6 were measured by immune assay methods. Thirty-two healthy subjects were included as a control group. Results: Serum levels of IL-6 and CRP were significantly higher in patients with CU compared to healthy controls (p < 0.001, p = 0.026 respectively). There was a statistically significant correlation among urticaria activity scores and IL-6 and CRP concentration (p = 0.004, p = 0.042). This correlation was more significant in patients who had moderate and severe disease activity scores than in those who had mild disease activity score (p < 0.001, p < 0.001, respectively). There was a statistically significant association between DLQI and IL-6 (p = 0.025). This correlation was very significant in patients who had severe and very severe disease activity scores (p < 0.001, p < 0.001, respectively). DLQI scores and serum levels of IL-6 were significantly different in the very severe group compared to healthy controls (p = 0.024). Conclusions: The levels of CRP and IL-6 are increased in patients with CU. A relationship of DLQI and urticaria activity scores with CRP and IL-6 was found. These findings support the relationship between the inflammatory process in CU and the clinical findings.Öğe Early-onset basal cell carcinoma(Turkish J Pediatrics, 2013) Turan, Enver; Yurt, Nurdan; Yesilova, Yavuz; Turkcu, GulBasal cell carcinoma (BCC) is a common skin cancer that is responsible for approximately 75% of non-melanoma skin cancers. BCC occurs on sun-exposed areas in fair-skinned individuals; frequency increases with age and peaks in the seventh decade of life. Although it usually occurs in the elderly population, it has been reported in children as well. Here, we present a case of BCC in an eight-year-old child without any predisposing characteristics.Öğe Effects of Isotretinoin on Social Anxiety and Quality of Life in Patients with Acne Vulgaris: A Prospective Trial(Croation Dermatovenerological Soc, 2012) Yesilova, Yavus; Bez, Yasin; Ari, Mustafa; Turan, EnverSocial anxiety is common in acne patients and the effects of isotretinoin treatment on social anxiety symptoms have not yet been thoroughly investigated. The aim of the study was to assess the effects of isotretinoin treatment on the quality of life and social anxiety symptoms in a group of acne vulgaris patients. The Liebowitz Social Anxiety Scale (LSAS) and Short Form-36 (SF-36) were administered to 39 (24 female and 15 male) patients with acne vulgaris who accepted isotretinoin treatment and agreed to participate in the study. The severity of acne was evaluated using the Global Acne Grading System. Thirty patients completed 6-month treatment with oral isotretinoin at 0.5-1.0 mg/kg daily doses. Measurements were repeated at the end of 6 months. Acne significantly improved over time in the study group. The mean performance avoidance score in LSAS and mean pain and social functioning scores in SF-36 were significantly better at the end of isotretinoin treatment. In conclusion, isotretinoin treatment improves the quality of life and social anxiety symptoms in acne patients.Öğe Nevus lipomatosus cutaneus superficialis associated with nevus sebaceous of Jadassohn(Medknow Publications & Media Pvt Ltd, 2014) Turan, Enver; Yesilova, Yavuz; Ucmak, Derya; Turkcu, Gul; Celik, Ozgur Ilhan; Gurel, Mehmet Salih[Abstract Not Available]Öğe Paederus Dermatitis: A Sporadic Case From Batman Region(Galenos Yayincilik, 2013) Turan, Enver; Yesilova, Yavuz; Ucmak, Derya; Yurt, Nurdan; Karakoca, Yeliz Basaran[Abstract Not Available]Öğe Reduced serum paraoxonase-1 levels in vitiligo: further evidence of oxidative stress(Taylor & Francis Ltd, 2012) Yesilova, Yavuz; Turan, Enver; Ucmak, Derya; Selek, Sahabettin; Yavuz, Brahim Halil; Tanrikulu, OsmanVitiligo is a common disorder that results in depigmented areas of the skin. The pathogenesis of the disease remains unclear, but oxidative stress is one suggested cause. Oxidative stress may be induced by increasing the generation of reactive oxygen species and other free radicals. The generation of reactive oxygen species is known to be associated with a decrease in antioxidant levels. This study examined oxidative stress index in active lesions of generalized vitiligo patients. We analysed serum levels of paraoxonase 1, arylesterase, catalase, ceruloplasmin, total antioxidant capacity, and oxidative stress index in patients with active lesions of generalized vitiligo, as well as in matched, healthy controls. Serum oxidants and oxidative stress indexes were higher, and serum antioxidants were lower, in vitiligo patients compared with healthy controls. Our findings suggest that oxidative stress may play an important role in the pathogenesis of vitiligo. Paraoxonase 1 can be used as an indicator in determining oxidative stress existent in the pathogenesis of vitiligo diseases.Öğe Thermal pillow: an unusual causative agent of erythema ab igne(Turkish J Pediatrics, 2013) Turan, Enver; Yesilova, Yavuz; Ucmak, Derya; Celik, Ozgur IlhanErythema ab igne (EAI), also known as toasted skin syndrome or heat-induced circumscribed dermal melanosis, presents with pigmented reticular skin lesions with telangiectasias due to prolonged thermal radiation exposure. This article describes a 16-year-old male patient with EAI due to the use of a thermal pillow, and discusses a potential causative agent of EAI. The potential hazards of misusing new technological equipment and the importance of consumer education are also discussed.
