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    Öğe
    Arteria femoralis varyasyonlarının multidedektör bilgisayarlı tomografi anjiografi yöntemi ile morfolojik incelenmesi
    (Dicle Üniversitesi, Sağlık Bilimleri Enstitüsü, 2021) Turan, Bilal; Tuncer, M. Cudi
    Amaç: Bu çalışmanın amacı, arteria femoralis (AF), arteria profunda femoris (APF), arteria circumflexa femoris medialis (ACFM) ve arteria circumflexa femoris lateralis (ACFL)’in hem klinik hem de cerrahi uygulamalar için gerekli olan anatomisinin multi dedektör bilgisayarlı tomografi (MDBT) görüntülerine dayalı analizini yapmaktı. Bu kapsamda damar paternlerinin varyasyonlarını ve çeşitli morfometrik ölçümlerin belirlenmesi amaçlandı. Gereç ve Yöntem: Çalışma Dicle Üniversitesi Tıp Fakültesi Radyoloji Anabilim dalı veri tabanından elde edilmiş retrospektif bir araştırmadır. 302’si (%75,5) erkek, 98’i (%24,5) kadın olmak üzere 400 bireyin sağ ve sol toplam 800 adet a. femoralis MBDT anjiografi görüntüleri incelenip çalışmaya dahil edildi. Çalışmadaki ölçümler uygun istatistiksel analizler yapılarak değerlendirildi. Bulgular: A. femoralis ve dallarının çok sayıda varyason tiplerine sahip olduğu bulundu. Çalışmada ACFM’in doğrudan AF’den (%24,87) ve APF ile ortak bir truncus şeklinde AF’den orjin aldığı varyasyon (%21,61) şekli en yüksek oranlarda tespit edildi. APF en çok a. femoralis’in posterolaterlinden orjin almaktaydı(%53). A. femoralis varyasyonlarının büyük çoğunluğunun unilateral yani tek taraflı olduğu belirlendi (%40,12). Sonuç: AF, APF, ACFM ve ACFL’nin önemli ve sık görülen varyasyonların bilinmesi, femoral bölgedeki invaziv ve non invaziv prosedürler sırasında bilinçli kararlar alınmasına yardımcı olacağı kanaatine varıldı.
  • [ X ]
    Öğe
    Morphological investigation of deep femoral artery variations using multidetector computed tomography angiography
    (Taylor & Francis Ltd, 2023) Turan, Bilal; Tuncer, Mehmet Cudi; Ertugrul, Ozgur Zulfikar; Cetincakmak, Mehmet Guli
    Purpose The deep femoral artery (DFA) is the largest and thickest branch of the femoral artery (FA), separated from the posterior lateral surface of the FA. This study aimed to analyze the anatomy of DFA using multidetector computed tomography (MDCT) angiography images to improve its clinical applications. Materials and methods Eight hundred right and left DFA MDCT angiography images from 400 individuals, 302 males (75.5%) and 98 females (24.5%), were included. Results It was determined that the DFA originates from six different aspects of the FA. The DFA was found to most commonly originate from the posterolateral aspect of the FA, with an incidence of 53%. The DFA originated from the posterior, lateral, medial, anterolateral, and posteromedial aspects at an incidence of 35.3%, 9.8%, 1%, %0.5, and 0.37%, respectively. The average distance between the DFA's origin and the midpoint of the inguinal ligament (IL) was 43.07 mm across both genders. The average distance between the DFA's origin and the midpoint of the IL was 43.07 mm. The average diameters of the DFA, medial circumflex femoral artery (MCFA), and lateral circumflex femoral artery (LCFA) were 5.62 mm, 3.01 mm, and 3.44 mm, respectively. The average distance between the DFA and MCFA was 14.64 mm, while between the DFA and LCFA, it was 19.05 mm. Conclusion Knowledge regarding the anatomical variants and morphology of the DFA will enhance the accuracy of decision-making during interventional procedures and operations in the femoral region, as well as aid in the prevention of iatrogenic injuries.
  • Küçük Resim
    Öğe
    Spreading depolarization: A phenomenon in the brain
    (University of Pisa, 2022) Aboghazleh, Refat; Alkahmous, Baraah; Turan, Bilal; Tuncer, Mehmet Cudi
    In 1944, the physiologist Leão while studying epilepsy in the rabbit noticed a sudden temporary cessation of electrocorticographic (ECoG) activity accompanied with a large negative slow potential change recorded by extracellular electrodes, that is later known as spreading depolarizations (SDs). The depression of the brain electrical activity was slowly propagating through the cerebral cortex. The mechanism of propagation is still controversial. SDs and seizures are following each other interchangeably, yet the puzzle needs more investigation to be clarified. SDs have an obvious effect on blood-brain barrier integrity mainly through transcellular and paracellular routs, but not much known about that especially following traumatic brain injury (TBI). The cortical spreading depolarization (CSD) and the depression of brain activity have been recognized following a variety of neurological diseases and brain injuries. CSD has been studied in animal models and recently in humans, and it has been recognized and described as a massive neuronal depolarization accompanied with high level of disturbances in transmembrane ion gradients and significant changes in cerebral blood flow1-3. Although there is a considerable amount of literatures on SD have been done since 1944, but the biophysical mechanism of SD, the long term effect on the brain structures and functions, and it is role in different disorders are still incompletely understood. Here, we summarize the history of spreading depolarization and the most accepted hypothesis for mechanism of initiation and propagation of that phenomenon. Most importantly, we present the most updated research on the relationship and interaction between spreading depolarization and traumatic brain injuries, seizure, blood-brain barrier, neurovascular coupling, and other neurological conditions. Learning more about the spreading depolarization will increase our understanding about that phenomenon and may explain its association with different clinical presentations.