Yazar "Toprak, Murat" seçeneğine göre listele

Listeleniyor 1 - 5 / 5
  • Küçük Resim
    Öğe
    Association of pain and clinical factors on disability and quality of life in systemic sclerosis: A cross-sectional study from Turkish League Against Rheumatism Network
    (Bayçınar Tıbbi Yayıncılık, 2023) Çevik, Remzi; Em, Serda; Nas, Kemal; Toprak, Murat; Cengiz, Gizem; Çalış, Mustafa; Sezer, İlhan; Enginar, Ayşe Ünal; Karslı, Pınar Bora; Sağ, Sinem; Sargın, Betül; Melikoğlu, Meltem Alkan; Aydın, Yıldıray; Duruöz, Mehmet Tuncay; Gezer, Halise Hande; Ecesoy, Hilal
    Objectives: In this study, we aimed to evaluate the factors associated with disability and quality of life (QoL) in Turkish patients with systemic sclerosis (SSc). Patients and methods: Between January 2018 and January 2019, a total of 256 SSc patients (20 males, 236 females; mean age: 50.9±12.4 years; range, 19 to 87 years) who were diagnosed with SSc were included in the study. Disability and health-related QoL (HRQoL) were evaluated by the Health Assessment Questionnaire (HAQ), scleroderma HAQ (SHAQ), Duruöz Hand Index (DHI), and Short Form-36 (SF-36). Linear regression analysis methods were used to describe factors associated with disability and QoL of the patients. Results: All disability scores were higher and HRQoL scores were lower in diffuse cutaneous SSc patients compared limited cutaneous SSc, and differentiations were significant (p=0.001 and p=0.007). In multiple regression, pain (VAS) was the strongest predictor for high disability and low QoL scores (p<0.001) as HAQ (β=0.397, 0.386, 0.452), SHAQ (β=0.397, 0.448, 0.372), DHI (β=0.446, 0.536, 0.389), PCS (β=-0.417,-0.499, -0.408) and MCS (β=-0.478, -0.441, -0.370) in combined, lcSSc and dcSSc patients respectively. The factors associated with high disability and low QoL scores were forced vital capacity for HAQ (β=-0.172, p=0.002) and SF-36 PCS (β=0.187, p=0.001); disease duration for HAQ (β=0.208, p<0.001), DHI (β=0.147, p=0.006), and SF-36 PCS (β=-0.134, p=0.014); 6-minute walk test for HAQ (β=-0.161, p=0.005) and SF-36 PCS (β=0.153, p=0.009); and modified Rodnan skin score for SHAQ (β=0.250, p<0.001) and DHI (β=0.233, p<0.001) in SSc patients. Diffusing capacity of the lungs for carbon monoxide for HAQ (β=-0.189, p=0.010) and SHAQ (β=-0.247, p=0.002); erythrocyte sedimentation rate for DHI (β=0.322, p<0.001); age for SF-36 PCS (β=-0.221, p=0.003) and body mass index for SF-36 PCS (β=-0.200, p=0.008) and MCS (β=-0.175, p=0.034) were the other variables associated with high disability or low QoL scores in SSc subsets. Conclusion: Clinicians should consider the management of the pain and its sources as a key to improve better functional state and quality of daily life in SSc.
  • [ X ]
    Öğe
    Decreased neck muscle strength in patients with the loss of cervical lordosis
    (Elsevier Sci Ltd, 2016) Alpayci, Mahmut; Senkoy, Emre; Delen, Veysel; Sah, Volkan; Yazmalar, Levent; Erden, Metin; Toprak, Murat
    Background: The loss of cervical lordosis is associated with some negative clinical outcomes. No previous study has examined cervical muscle strength, specifically in patients with the loss of cervical lordosis. This study aims to investigate whether there is weakness of the cervical muscles or an imbalance between cervical flexor and extensor muscle strength in patients with the loss of cervical lordosis compared with healthy controls matched by age, gender, body mass index (BMI), and employment status. Methods: Thirty-two patients with the loss of cervical lordosis (23 F, 9 M) and 31 healthy volunteers (23 F, 8 M) were included in the study. Maximal isometric neck extension and flexion strength, and the strength ratio between extension and flexion were used as evaluation parameters. All measurements were conducted by a blinded assessor using a digital force gauge. The participants were positioned on a chair in a neutral cervical position and without the trunk inclined during measurements. Findings: Maximal isometric neck extension and flexion strength values were significantly lower in the patients versus healthy controls (P<0.001 and P = 0.040, respectively). The mean (SD) values of the extension/flexion ratio were 1.21 (0.34) in the patients and 1.46 +/- 0.33 in the controls (P = 0.004). Interpretation: According to our results, patients with the loss of cervical lordosis have reduced neck muscle strength, especially in the extensors. These findings may be beneficial for optimizing cervical exercise prescriptions. (C) 2016 Elsevier Ltd. All rights reserved.
  • [ X ]
    Öğe
    The frequency and effect of fibromyalgia in patients with Behcet's disease
    (Baycinar Medical Publ-Baycinar Tibbi Yayincilik, 2017) Toprak, Murat; Erden, Metin; Alpayci, Mahmut; Ediz, Levent; Yazmalar, Levent; Hiz, Ozcan; Tekeoglu, Ibrahim
    Objectives: This study aims to investigate the scores of depression, anxiety, sleep and quality of life (QoL), to identify the prevalence of fibromyalgia (FM) in Behcet's disease (BD), and to evaluate whether there is a difference between BD patients with and without FM in these scores. Patients and methods: Between March 2008 and January 2009, 97 patients with BD and 95 age- and sex-matched healthy controls were included in the study. The patients with BD were divided into two groups according to the presence or absence of FM. All participants were evaluated by the Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), Pittsburgh Sleep Quality Index (PSQI), and Medical Outcomes Study Short Form-36 (SF-36). Results: Compared to the controls, FM prevalence was higher (19.6% vs 3.2%) with increased BDI and BAI scores, while the subscores of SF-36 including physical function, physical role, pain, general health, social function, and emotional role decreased in BD patients (for all p<0.001). All BD patients with FM were females (n=19), while only 46% of BD patients without FM were females (n=36) (p<0.001). In BD patients with FM, compared to female BD patients without FM, the mean age (p=0.017), disease duration (p=0.028), and BDI scores (p=0.017) were significantly higher, while the PSQI scores (p=0.001) and SF-36 subscores, except general health (p=0.114), were significantly lower (for all p<0.05). Conclusion: Our study results suggest that patients with BD have an increased severity of depression and anxiety, higher frequency of FM, and worsened QoL than healthy individuals. In addition, the presence of FM seems to be related with female sex, longer disease duration, older age, depression, sleep disturbance, and poor QoL in BD patients.
  • [ X ]
    Öğe
    The frequency and effect of fibromyalgia in patients with Behçet’s disease
    (2017) Ediz, Levent; Erden, Metin; Tekeoğlu, İbrahim; Alpaycı, Mahmut; Yazmalar, Levent; Toprak, Murat; Hız, Özcan
    This study aims to investigate the scores of depression, anxiety, sleep and quality of life (QoL), to identify the prevalence offibromyalgia (FM) in Behçet’s disease (BD), and to evaluate whether there is a difference between BD patients with and without FM in thesescores.Patients and methods: Between March 2008 and January 2009, 97 patients with BD and 95 age- and sex-matched healthy controls wereincluded in the study. The patients with BD were divided into two groups according to the presence or absence of FM. All participants wereevaluated by the Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), Pittsburgh Sleep Quality Index (PSQI), and MedicalOutcomes Study Short Form-36 (SF-36).Results: Compared to the controls, FM prevalence was higher (19.6% vs 3.2%) with increased BDI and BAI scores, while the subscores of SF-36including physical function, physical role, pain, general health, social function, and emotional role decreased in BD patients (for all p<0.001). AllBD patients with FM were females (n=19), while only 46% of BD patients without FM were females (n=36) (p<0.001). In BD patients with FM,compared to female BD patients without FM, the mean age (p=0.017), disease duration (p=0.028), and BDI scores (p=0.017) were significantlyhigher, while the PSQI scores (p=0.001) and SF-36 subscores, except general health (p=0.114), were significantly lower (for all p<0.05).Conclusion: Our study results suggest that patients with BD have an increased severity of depression and anxiety, higher frequency of FM,and worsened QoL than healthy individuals. In addition, the presence of FM seems to be related with female sex, longer disease duration,older age, depression, sleep disturbance, and poor QoL in BD patients.
  • [ X ]
    Öğe
    The relationship between facet joint osteoarthritis and Modic changes of the lumbar spine: a retrospective magnetic resonance imaging study
    (Baycinar Medical Publ-Baycinar Tibbi Yayincilik, 2016) Alpayci, Mahmut; Bulut, Mehmet Deniz; Yazmalar, Levent; Yavuz, Alpaslan; Toprak, Murat; Koparan, Ibrahim Halil; Gulsen, Ismail
    Objectives: This study aims to assess the facet joint osteoarthritis in patients with lumbar Modic changes and to investigate the relationship between the Modic types and severity of the facet joint degeneration. Patients and methods: A total of 120 patients (55 males, 65 females; mean age 55.18 +/- 9.47 years; range 40 to 75 years) were included in the study. The patients were divided into four equal groups of 30 patients according to Modic type (No Modic changes, type 1, type 2, type 3). All groups were matched with age, sex, and spinal level. A total of 180 lumbar facet joints of the patients with Modic changes (60 facet joints for each Modic type) and 60 lumbar facet joints of the patients without Modic changes were analyzed. The severity of the facet joint osteoarthritis was assessed. The degree of the facet degeneration was evaluated by using the Pathria grading system with magnetic resonance imaging. Results: Facet joint degeneration increased gradually, as the type of Modic change increased. Compared to the group without Modic changes, all three groups with Modic changes had more degenerative facet joints (all p <= 0.002). The severity of the facet joint degeneration was significantly higher in type 3 versus type 1 Modic changes (p=0.022). Conclusion: Our study results suggest that Modic changes, particularly type 3, are strongly associated with the facet joint osteoarthritis of the lumbar spine. Clinically, facet joint degeneration should be considered in the examination of low back pain inpatients with Modic changes.