Yazar "Tolan V." seçeneğine göre listele

Listeleniyor 1 - 3 / 3
  • [ X ]
    Öğe
    Chemical composition, antimicrobial and antioxidant activities of hyssop (Hyssopus officinalis L.) essential oil
    (2010) Kizil S.; Haşimi N.; Tolan V.; Kilinç E.; Karataş H.
    The essential oil of hyssop is widely used in food, pharmaceutical and cosmetic industries throughout the world. Therefore, it is very important to know the chemical characteristics of the oil for economic use and enhanced performance of the end products. This study was carried out to determine antimicrobial and antioxidant activities of the essential oil of Hyssopus officinalis (L.) (Lamiaceae) collected from wild in the Southeast Anatolian, Turkey. Chemical compositions of hydrodistilled essential oils obtained from hyssop leaves were analyzed by gas chromatography-mass spectrometry (GC-MS). For antimicrobial activity, disc diffusion tests were carried out on Escherichia coli line ATCC25922, Pseudomonas aeroginosa line ATCC27853, Staphylococcus aureus line 25923, Staphylococcus pyogenes line ATCC19615 and Candida albicans line ATCC10231, and the antioxidant activity was determined by using the diphenylpicrylhydrazyl (DPPH) radical-scavenging method. It was determined that hyssop essential oil contained isopinocamphone (57.27%), (-)-?-pinene (7.23%), (-)-terpinen-4-ol (7.13%), pinocarvone (6.49%), carvacrol (3.02%), p-cymene (2.81%) and myrtenal (2.32%) as major components. As shown by treatments with 5 and 10 ?l of oil; which exhibited strong antimicrobial activity against S. pyogenes, S. aureus, C. albicans and E. coli, but not against P. aeruginosa. The antioxidant activity of H. officinalis essential oil was lower compared to butylated hydroxytoluene (BHT) and ascorbic acid. These results demonstrated that hyssop essential oil has relatively low antioxidant activity and good antimicrobial activity against some test organisms.
  • [ X ]
    Öğe
    Evaluation of antioxidant, cholinesterase inhibitory and antimicrobial properties of Mentha longifolia subsp. noeana and Its secondary metabolites
    (ACG Publications, 2015) Ertaş A.; Gören A.C.; Haşimi N.; Tolan V.; Kolak U.
    The aim of the present study was to determine the chemical structures of the isolated compounds, the essential oil and fatty acid compositions of Mentha longifolia subsp. noeana with their biological activities. Ursolic acid (1), uvaol (2), stigmast-5-ene-3?-yl formate (3), stigmast-5-en-3-one (4), ?-sitosterol (5), bis(2- ethylhexyl) benzene-1,2-dicarboxylate (6), hexacosyl (E)-ferulate (7) and 5-hydroxy-6,7,3',4'-tetramethoxy flavone (8) were obtained from the aerial parts. The compounds (2-4, 6, 7) were isolated for the first time from a Mentha species. Palmitic acid (40.8%) was the major component of the non-polar fraction obtained from the petroleum ether extract. Pulegone (32.3%) was the main constituent of the essential oil which exhibited strong butyrylcholinesterase inhibitory activity (77.36 ± 0.29%), moderate antimicrobial activity against Escherichia coli, Staphylococcus aureus, and Candida albicans. The methanol extract showed 80% inhibition of lipid peroxidation, and the acetone extract possessed moderate DPPH free radical scavenging activity (60% inhibition) at 100 ?g/mL. © 2015 ACG Publications. All rights reserved.
  • [ X ]
    Öğe
    Genotoxicity of essential oil of thymbra spicata l. var spicata in salmonella/microsome and sos chromotest
    (2009) Tolan V.; Kizil S.; Özdemir S.; Demirci O.
    Essential oils are concentrated, hydrophobic liquid containing volatile aroma compounds from plants, which are called aromatic herbs or aromatic plants. Various essential oils and their monoterpenoid constituents have been widely used as fragrances in cosmetics, as flavouring food additives, and as scenting agents in a variety of household products. The present study was undertaken to investigate the mutagenic potential of essential oil of Thymbr? spic?t? L. var spic?t? by S?lmonell?/ mic?osome assay TA98 and TA100 tester strains, and also SOS chromotest with E.coli PQ37 strain, with and without addition of an S9 metabolic activation mixture. The essential oil of T. spic?t? L. var spic?t? showed weakly mutagenic activity on both strains of Salmonella either without or with S9 mixture. No mutagenicity was found in the SOS chromotest either with or without S9 mixture. These results indicate a weak mutagenicity of the essential oil of Thymbra spicata in vitro.