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Öğe A complicated case of pericardial hydatid cyst manifesting as constrictive pericarditis(Pulsus Group Inc, 2000) Karadede, A; Ülgen, MS; Temamogullari, AV; Toprak, NAlthough cardiac involvement with hydatid cyst is quite rare as a major complication, constrictive pericarditis is even less common. A 55-year-old man is presented in whom a hydatid cyst located in the right cardiophrenic angle anterior to the right ventricle ruptured into the pericardial sac, resulting in constrictive pericarditis.Öğe Relation between QT dispersion and ventricular arrhythmias in uncomplicated isolated mitral valve prolapse(Blackwell Science Asia, 1999) Ülgen, MS; Biyik, I; Karadede, A; Temamogullari, AV; Alan, S; Toprak, NComplications of mitral valve prolapse (MVP), among which serious ventricular arrhythmia and sudden death are of major importance, affect many individuals due to the high incidence of MVP itself in the community despite the actual low incidence of these complications. The present study investigated the incidence and distribution of ventricular arrhythmias according to their severity and relationship with the QT interval and dispersion of repolarization in uncomplicated isolated MVP (IMVP) cases. Fifty-eight uncomplicated IMVP patients, 33 patients with accompanying tricuspid valve prolapse (TVP), to compare its relationship with ventricular arrhythmia, and 60 age- and sex-matched control subjects were enrolled in the study. Individuals with accompanying cardiac or systemic disease, or who were on drug therapy that could potentially affect QT characteristics, were excluded. The incidence of ventricular arrhythmia was 48% in the IMVP group and 64% in the TVP group; the difference was statistically insignificant. In addition, the differences of the QT and Q peak T values were insignificant, whereas QT dispersion (QTd) and Q peak T dispersion (QpeakTd) values were significantly higher in the patient group (60+/-14, 54+/-14 ms, respectively) compared with the control group (42+/-10, 38+/-10 ms, respectively, p<0.001). Complex ventricular arrhythmias (Lown Grade greater than or equal to III) in the IMVP group had a significant relationship with QTd and QpeakTd (p<0.001), but not with QT or QpeakT. As a result of the study, it is concluded that TVP accompanying MVP does not increase the incidence of ventricular arrhythmia, that ventricular arrhythmia is related to QT dispersion rather than QT interval in IMVP, that the QT dispersion is a fairly good marker for identifying the high-risk group for serious ventricular arrhythmia and sudden death, and that QpeakT dispersion measurement is an additional indicator that could be an alternative when QT is difficult to determine in conditions such as high heart rate or the presence of U wave.Öğe The relationship of ST segment elevation shape with preserved myocardium and signal-averaged electrocardiography in acute anterior myocardial infarction(Springer-Verlag, 2002) Karadede, A; Aydinalp, O; Temamogullari, AV; Toprak, NAlthough a relation between magnitude of ST segment elevation and myocardial damage has been shown in the early period of acute myocardial infarction (AMI), such a relation between the shape of the ST segment elevation, myocardial damage, and the clinical course remains obscure. For this purpose 62 first anterior AMI patients admitted in the first 6h were enrolled for the study. On the basis of precordial V3 derivation prior to thrombolytic therapy, the shape of the ST elevation was separated into three groups: concave (n = 26). straight (n = 24), or convex types (n = 12). The relation between the shape of the ST elevation recorded on admission, and the results of pre-discharge low-dose dobutamine stress echocardiography (LDE) performed (n = 53) and signal-averaged ECG values were investigated. The basal wall motion score index (WMSI) and response to LDE in the concave group were better in the infarct zone. Additionally, the average akinetic segment number in the infarct zone was higher, and improvement in these segments was less in the convex and straight groups (concave 3.78 +/- 2 vs 2.17 +/- 2.1. P < 0.01: straight 5.15 +/- 2.7 vs 4.45 +/- 2.8, not significant (NS) convex 5.4 +/- 2.3 vs 4.8 +/- 2.1, NS: basal vs LDE), While only 13% (3/23) of the patients did not respond to LDE (P < 0.05 vs group B and P < 0.01 vs group C), 35% (7/20) of group B and 60% (6/10) of group C patients did not respond to LDE. Although no relation was found between better left ventricular function (WMSI < 2) and shape of the ST elevation in basal evaluation by multiple logistic regression analysis (P = 0.06), an independent relation was found between them following LDE (P = 0.01, odds ratio (OR) 4.5, 95% Confidence Interval (CI) 1.3-14.7). The incidence of ventricular late potential (LP) positivity was 11% (3/26) in the concave group, 16% (4/24) in the straight group. and 58% (7/12) in the convex group (P < 0.001 vs concave and P < 0.05 vs straight groups). We found that shape of the ST elevation could significantly predict the presence of late potentials in multiple logistic regression analysis (P = 0.003, OR 10.7, 95% CI 2.2-51.7). There was no in-hospital death in the concave group, whereas five patients died in either the straight or the convex group. Furthermore, arrhythmia was lower in the concave group during this period (P < 0.05), and exercise capacity was lower. In conclusion, we determined that there wits it higher viable myocardium, and lower LP(positivity) and in-hospital mortality in patients with concave ST elevation on admission.