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    The frequency and effect of fibromyalgia in patients with Behçet’s disease
    (2017) Ediz, Levent; Erden, Metin; Tekeoğlu, İbrahim; Alpaycı, Mahmut; Yazmalar, Levent; Toprak, Murat; Hız, Özcan
    This study aims to investigate the scores of depression, anxiety, sleep and quality of life (QoL), to identify the prevalence offibromyalgia (FM) in Behçet’s disease (BD), and to evaluate whether there is a difference between BD patients with and without FM in thesescores.Patients and methods: Between March 2008 and January 2009, 97 patients with BD and 95 age- and sex-matched healthy controls wereincluded in the study. The patients with BD were divided into two groups according to the presence or absence of FM. All participants wereevaluated by the Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), Pittsburgh Sleep Quality Index (PSQI), and MedicalOutcomes Study Short Form-36 (SF-36).Results: Compared to the controls, FM prevalence was higher (19.6% vs 3.2%) with increased BDI and BAI scores, while the subscores of SF-36including physical function, physical role, pain, general health, social function, and emotional role decreased in BD patients (for all p<0.001). AllBD patients with FM were females (n=19), while only 46% of BD patients without FM were females (n=36) (p<0.001). In BD patients with FM,compared to female BD patients without FM, the mean age (p=0.017), disease duration (p=0.028), and BDI scores (p=0.017) were significantlyhigher, while the PSQI scores (p=0.001) and SF-36 subscores, except general health (p=0.114), were significantly lower (for all p<0.05).Conclusion: Our study results suggest that patients with BD have an increased severity of depression and anxiety, higher frequency of FM,and worsened QoL than healthy individuals. In addition, the presence of FM seems to be related with female sex, longer disease duration,older age, depression, sleep disturbance, and poor QoL in BD patients.