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Öğe The association between mean platelet volume and coronary collateral circulation(Verduci Publisher, 2013) Islamoglu, Y.; Ertas, F.; Acet, H.; Elbey, M. A.; Evliyaogllu, O.; Tekbas, E.; Cil, H.BACKGROUND: Platelets are important in the pathogenesis of atherosclerotic complications. Higher mean platelet volume (MPV) levels are related to greater in vitro aggregation, and have been identified as an independent risk factor for myocardial infarction, and for death or recurrent vascular events. AIM: To determine the relationship between MPV and the coronary collateral circulation. METHODS: The sample consisted of 96 patients with coronary artery disease, and patients were separated into two groups according to their poorly developed or well-developed collateral circulation. Coronary collateral vessels were analyzed according to the Cohen and Rentrop grading system of 0-3. RESULTS: All analyses were conducted using SPSS 11.5 (SPSS for Windows 11.5, Chicago, IL, USA). Continuous variables were expressed as mean +/- SD, and categorical variables were expressed as percentages. Comparison of categorical and continuous variables between the group with well-developed coronary collateral vessels and the group with poorly developed vessels was performed using the chi-squared test and independent samples t-test, respectively. Platelet count and MPV values were similar between the two groups. CONCLUSIONS: Our study found that MPV levels are not related to coronary collateral circulation.Öğe Effect of hypoglycemic drugs on aspirin resistance in patients with diabetes mellitus(Verduci Publisher, 2012) Ariturk, Z.; Islamoglu, Y.; Gunduz, E.; Yavuz, C.; Cil, H.; Tekbas, E.; Soydinc, S.Background: Aspirin reduces the odds of an arterial thrombotic event in high-risk patients. However, 10%-20% of patients with an arterial thrombotic event who are treated with aspirin have a recurrent arterial thrombotic event during long-term followup. Aspirin resistance has been described in some patient populations such as those with an acute coronary syndrome, ischemic stroke, percutaneous coronary intervention with drug-eluting stent, stent re-stenosis, and diabetes mellitus (DM). The aim of this study was to assess aspirin resistance and to compare it to the use of oral anti-diabetic drugs and insulin in patients with diabetes. Methods and Results: Platelet aggregation was measured after aspirin treatment in 101 diabetic patients undergoing percutaneous coronary intervention. Two patient populations were included in the investigation: use of insulin (group 1) and use of oral anti-diabetic agents (OAD) (group 2) in diabetic patients. Platelet aggregation was determined using a multichannel Multiplate analyzer. Among group 1 patients, 4.7% were aspirin non-responders and among group 2 patients, 8.6% were aspirin non-responders. Statistical differences were not found between the groups (p = 0.359). Conclusions: This study demonstrated that there was no significant difference in aspirin resistance between type 2 diabetes mellitus patients on insulin treatment and type 2 diabetes mellitus patients on OAD treatment.Öğe ENTRAPPED THROMBUS IN PATENT FORAMEN OVALE COMPLICATED BY PULMONARY EMBOLISM(Elsevier Ireland Ltd, 2011) Elbey, M. A.; Acet, H.; Cil, H.; Islamoglu, Y.; Tekbas, E.; Ariturk, Z.[Abstract Not Available]Öğe Evaluation of pulmonary vein variations in the middle pulmonary lobe with 64-slice multidetector computed tomography(Verduci Publisher, 2011) Tekbas, G.; Ekici, F.; Tekbas, E.; Gumus, H.; Onder, H.; Bilici, A.; Yavuz, C.Purpose: To evaluate the multi detector computed tomographic (CT) depiction of middle lobe vein variation of the right pulmonary vein and create a diagram for cardiologist and cardiovascular surgeons. Materials and Methods: According to hospital records, between January 2009 and April 2010, 314 consecutive patients underwent pulmonary CT angiography (CTPA) and coronary CT angiography. The CT films from these patients were retrospectively analyzed. Results: Under normal conditions, the middle pulmonary vein (MPV) drains into the left atrium either by the direct or indirect route. Direct (37 patients, 11.8%) drainage means that the MPV does not drain into the upper or lower pulmonary veins but instead drains directly into the right pulmonary vein system. In contrast, indirect (276 patients, 87.9%) drainage occurs when the MPV drains into the upper or lower pulmonary veins. In this study, 12 different variations in drainage patterns were found. Conclusion: Increasing the number of patients may have led to the identification of additional variants. However, clinically important variations are rarely seen. Correct mapping of the MPV is very important for cardiologists and for surgeons in order to provide the best treatment and avoid complications.Öğe GUNSHOT INJURY OF THE HEART: AN UNUSUAL LOCALIZATION OF BULLET FRAGMENT(Elsevier Ireland Ltd, 2011) Elbey, M. A.; Yavuz, C.; Islamoglu, Y.; Cil, H.; Atilgan, Z.; Tekbas, E.[Abstract Not Available]Öğe Increased echocardiographic epicardial fat thickness is related to impaired diurnal blood pressure profiles(Oxford Univ Press, 2013) Ertas, F.; Kaya, H.; Acet, H.; Cil, H.; Akyuz, A.; Islamoglu, Y.; Tekbas, E.[Abstract Not Available]Öğe Increased epicardial fat thickness is related with body mass index in women with polycystic ovary syndrome(Verduci Publisher, 2013) Soydinc, E.; Soydinc, S.; Ariturk, Z.; Tekbas, E.; Cakici, M.; Islamoglu, Y.; Ercan, S.AIM: We aimed to investigate the relationship between PCOS and epicardial fat thickness with transthoracic echocardiography. PATIENTS AND METHODS: PCOS patients were divided into two groups according to the lean or obesity status: PCOS patients with lean 34 subjects (BMI: 23.3+/-2.8; mean age: 25.5+/-4), PCOS patients with obese16 subjects (BMI: 32.3+/-7.6; mean age: 27.2+/-3.7) were compared with control healthy lean subjects (BMI: 23.5+/-1.7; mean age: 25.9+/-2.2). RESULTS: There was increased epicardial thickness in obese PCOS subjects compared to lean PCOS subjects (6.3+/-0.9 mm, 4.7+/-0.5, respectively, p < 0.001). However, epicardial fat thickness between lean PCOS subjects and lean healthy control groups were not significantly varied (4.7+/-0.5 mm, 4.5+/-0.5, respectively, p = 0.6). There was increased epicardial thickness in obese PCOS subjects compared to lean healthy control subjects (6.3+/-0.9 mm, 4.5+/-0.5, respectively, p < 0.001). This sudy showed for the first time that increased epicardial fat thickness measured using transthoracic echocardiography is associated with increased BMI in PCOS subjects. CONCLUSIONS: Epicardial fat thickness between lean PCOS subjects and lean healty control group were similar which indicate the importance of obesity in PCOS subjects.Öğe SAFETY AND EFFICACY OF IBUTILIDE DURING ATRIAL FIBRILLATION ABLATION(Elsevier Ireland Ltd, 2011) Aktas, M. K.; Islamoglu, Y.; Tekbas, E.; Cil, H.; Ariturk, Z.; Elbey, M. A.; Guler, A.[Abstract Not Available]Öğe STENT FRACTURE(Elsevier Ireland Ltd, 2011) Ariturk, Z.; Tekbas, E.; Islamoglu, Y.; Soydinc, S.; Davutoglu, V.; Cil, H.; Elbey, M. A.[Abstract Not Available]Öğe AN UNUSUAL PRESENTATION OF HYPERTHYROIDISM: ATRIOVENTRICULAR COMPLETE HEART BLOCK(Editura Acad Romane, 2011) Ariturk, Z.; Islamoglu, Y.; Tekbas, E.; Cil, H.; Soydinc, S.; Yazici, M.Complete heart block associated with hyperthyroidism is infrequent, and the diagnosis of hyperthyroidism is usually not considered in the absence of tachycardia. A 55-year-old woman was admitted to our emergency clinic with dizziness and syncope attack. Her electrocardiogram showed complete heart block. Hyperthyroidism had been diagnosed. and she had been treated with propylthiouracil as an anti-thyroid treatment 3 years ago, although she had not taken this drug during the last 2 months. Her thyroid Junction tests showed hyperthyroidism. Antithyroid treatment was started again. Her rhythm returned from complete atrioventricular block to normal sinus rhythm on the seventh day of hospitalization.
