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Öğe Aggressive periodontitis associated with Kindler syndrome in a large Kindler syndrome pedigree(Turkish J Pediatrics, 2017) Yildirim, Tuba Talo; Kaya, Filiz Acun; Taskesen, Mustafa; Dundar, Serkan; Bozoglan, Alihan; Tekin, Gulucag Giray; Akdeniz, SedatKindler syndrome (KS) is a rare genetic disorder. The clinical features include aggressive periodontal disease and severe desquamative gingivitis. Five individuals with KS were assessed by oral examination, radiographic analysis and periodontal measurements. All the patients' indexes were recorded prior to periodontal treatment and at the end of the 1th, 3th, 6th, 9th and 12th month respectively. All the patients had improvement of periodontal status and enhancement in index scores. The affected individuals were previously screened for FERMT1 mutations. KS patients' periodontal disease activity could be taken under control with regular follow-up.Öğe Brainstem involvement in subacute sclerosing panencephalitis(Turkish J Pediatrics, 2010) Yaramis, Ahmet; Taskesen, MustafaSubacute sclerosing panencephalitis (SSPE), which usually develops 2-10 years after measles infection, is a progressive neurologic disorder with an insidious onset. The neurologic dysfunctions associated with SSPE include generalized myoclonic jerks and seizure activity, and progression of the disease usually results in coma and death within one to two years after onset. Most of the cerebral lesions in SSPE are observed in the periventricular and subcortical white matter. Brainstem involvement in SSPE is very rare. In this paper, we report two cases with brainstem involvement in SSPE that was accompanied by other intracranial lesions with magnetic resonance imaging (MRI). These two patients died in a short time. Thus, brainstem involvement should be considered in patients with SSPE.Öğe Clinical and cranial magnetic resonance imaging (MRI) findings of 21 patients with serious hyperbilirubinemia(Sage Publications Inc, 2008) Katar, Selahattin; Akay, Hatice Ozturkmen; Taskesen, Mustafa; Devecioglu, CelalThis study aims to compare neurological examination and cranial magnetic resonance imaging (MRI) findings in patients with serious hyperbilirubinemia. Twenty-one serious hyperbiluribinemic term neonates (6 girls, 15 boys) who underwent exchange transfusions were included in the study. Neurological examination findings, body weight, age at admission, blood culture, urine culture, urine analysis, C-reactive protein, thyroxine, thyroid-stimulating hormone, total and indirect bilirubin levels, causes of hyperbilirubinemia (blood group typing, glucose-6-phosphate dehydrogenase, blood smear, tandem mass), treatment and duration of follow-up, auditory test results, and cranial MRI findings were evaluated. All patients were term neonates with an average body weight of 2943 +/- 533 g. The mean age at admission was 4.47 +/- 2.22 days, and the mean bilirubin level was 35.0 +/- 10.8 mg/dL. Exchange transfusion was performed once in all, except 4 patients who needed 2 transfusions. Kernicterus findings were found in 76% of patients on neurological examination, and cranial MRI detected a pathological finding in 71% of patients. In 2 patients, cranial MRI showed kernicterus findings, despite normal neurological examination. In contrast, in 3 patients, despite kernicterus findings in neurological examination, cranial MRI was normal. Although cranial MRI has an important place in the diagnosis of kernicterus, it does not always correlate with clinical findings. We believe that studies with larger series are warranted.Öğe Cranial magnetic resonance imaging findings of nutritional Vitamin B12 deficiency in 15 hypotonic infants(Elsevier Sci Ltd, 2012) Taskesen, Mustafa; Yaramis, Ahmet; Pirinccioglu, Ayfer Gozu; Ekici, FaysalBackground: Nutritional vitamin B-12 deficieny is common among infants in the developing and underdeveloped countries. There is limited information concerning neuroimaging findings in infants with vitamin B-12 deficiency in the literature. Aims: The aim of this study is to evaluate the cranial magnetic resonance imaging (MRI) changes and clinical characteristics of hypotonic infants due to vitamin B-12 deficiency. Materials and methods: A total of 15 infants with neuroradiologic investigations were diagnosed with nutritional B-12 vitamin deficiency. Cranial MRI was performed on all infants. Results: Five infants were female (33%) and the mean age of infants was 12.3 +/- 5.5 months. Hypotonia and neurodevelopmental retardation were present in all patients. MRI demonstrated thinning of the corpus callosum in 6 (40%), cortical atrophy in 5 (33.3%), large sylvian fissures in 5 (33.3%), ventricular dilatation in 3 (20%), asymetric large lateral ventricle in 2 (13.3%) and delayed in myelination in 2(13.3%) patients. Four infants had normal MRI findings. Conclusion: Because of the importance of vitamin B-12 in the development of the brain, MRI findings may be detected and useful in infants with vitamin B-12 deficiency. (C) 2011 European Paediatric Neurology Society. Published by Elsevier Ltd. All rights reserved.Öğe Diameters of normal thoracic vascular structures in pediatric patients(Springer France, 2009) Akay, Hatice Ozturkmen; Ozmen, Cihan Akgul; Bayrak, Aylin Hasanefendioglu; Senturk, Senem; Katar, Selahattin; Nazaroglu, Hasan; Taskesen, MustafaPurpose To determine the normal range of aortic and pulmonary artery diameters on chest CT, and to search a constant ratio when the diameters of thoracic vascular structures are compared with an internal reference. Methods Contrast-enhanced chest CT scans of 133 pediatric patients were retrospectively evaluated. Diameters of ascending and descending aorta, main pulmonary artery, right and left pulmonary arteries and a constant thoracic vertebra were measured. The mean ratios of thoracic vascular diameters to the diameter of the thoracic vertebra were calculated. Results There was a positive correlation between the age of the patients and vascular diameters. The mean ratios of vascular diameters to the diameter of thoracic vertebra, ranged from 1.1 for the ascending aorta to 0.70 for the right and left pulmonary arteries, were consistent. Conclusions Diameters of thoracic vascular structures increase with age. The consistent vertebral to vessel ratios can be useful in evaluation of chest CT of pediatric patients.Öğe Elevated Plasma Levels of N-terminal pro-Brain Natriuretic Peptide in Children with Acute Poststreptococcal Glomerulonephritis(Tohoku Univ Medical Press, 2009) Taskesen, Mustafa; Taskesen, Tuncay; Katar, Selahattin; Karadede, Abduelaziz; Tas, Mehmet AliAcute poststreptococcal glomerulonephritis (APSGN) is the most common prototype of acute glomerulonephritis in children, and is characterized by the sudden onset of gross hematuria, edema, hypertension and volume overload. Brain natriuretic peptide (BNP) is produced in both the brain and the heart. Its prohormone, proBNP, is cleaved to biologically active BNP and an inactive N-terminal peptide of proBNP (NT-proBNP). NT-proBNP is released predominantly from the ventricles in response to hypervolemia and pressure overload. We therefore investigated the relationship between NT-proBNP levels and cardiac functions of patients with APSGN. NT-proBNP levels were measured in 28 patients with APSGN (17 boys and 11 girls of 8.2 +/- 2.9 years old) and in 26 healthy children (control group). Echocardiograms were performed in both patient and control groups on admission, and only in the patient group two weeks later. Upon admission, the plasma NT-proBNP levels were higher in the patients than in the control group (8876.2 +/- 9650.8 vs 69.5 +/- 22.2 pg/mL, p < 0.001), and left ventricular dysfunction was detected in six patients. Moreover, NT-proBNP levels were significantly higher in the patients with left ventricular dysfunction than other patients (n = 22). There was no significant difference in the levels of NT-proBNP between the patient and control groups, after diuretic treatment of the patients. Plasma NT-proBNP levels were positively correlated with the severity of APSGN. Thus, NT-proBNP level may be a useful marker to assess the volume overload and cardiac function in the follow up of selected APSGN patients.Öğe Etkisi The Effect of Transport on Mortality and Morbidity in Preterm Infants Less than 32 Weeks of Gestation(Galenos Yayincilik, 2014) Katar, Selahattin; Yildiz, Dogan; Turgut, Abdulkadir; Taskesen, Mustafa; Saka, GunayIntroduction: The aim of this study was to compare mortality and morbidity rates of premature infants with gestational age of less than 32 weeks who were born in our hospital and those who were transported to our hospital after birth from other centers. Materials and Methods: Patients were divided into two groups; Group 1 included 40 patients who were born before gestational age of 32 weeks in our hospital, and Group 2 included 108 premature patients who were born before gestational age of 32 weeks in other centers and later transferred to our hospital. Morbidity and mortality rates were compared between the two groups (intraventricular hemorrhage (IVH), retinopathy of prematurity (ROP), respiratory distress syndrome (RDS), necrotizing enterocolitis (NEC), and bronchopulmonary dysplasia (BPD)). Results: Demographic characteristics, gender, body weight, and gestational age were similar in both groups (p> 0.05). The rate of normal vaginal delivery births was higher in Group 2 (p< 0.001). On admission, hypothermia was detected in 90% of the patients and hypoglycemia was found in 2.7% of patients in Group 2. Mortality was higher in Group 2 than in Group 1, however the difference was not significant (p> 0.05). Although higher rates of IVH, ROP, RDS, NEC, and BPD were found in Group 2, there was no statistically significant difference between the two groups (p> 0.05). Conclusions: Being transferred after birth has a negative effect on morbidity and mortality in premature infants. Thus, the best transport method is intrauterine transport except in state of an emergency, especially for infants with severe prematurity; these patients should be treated in centers with facilities of the highest level.Öğe Evaluation of Tracheostomy Patients in Our Pediatric Intensive Care Unit: A Single-Center Study(Springernature, 2024) Kolbasi, Baris; Senkal, Emine; Taskesen, MustafaObjectives: A tracheostomy is a surgical procedure that can be performed on critically ill patients of all ages in intensive care units as indicated, and its use has been increasing in recent years. The most common indications are prolonged mechanical ventilation and upper airway obstruction. This study aimed to examine the indications for tracheostomy, assess the outcomes of patients who underwent the procedure, and identify the factors affecting these outcomes. Material and method: A retrospective analysis of patients who underwent tracheostomy between 2013 and 2019 at Dicle University Faculty of Medicine Hospital Paediatric Intensive Care Unit (PICU). The patients' age, gender, distribution by age, primary diagnosis at admission to the intensive care unit, indication for tracheostomy, presence of additional disease, type of respiratory support before and after tracheostomy, development of complications (perioperative/postoperative), decannulation status, mortality, and discharge status were recorded. Results: A total of 61 patients were enrolled into the study. The average age of the patients was 81.72 months (SD = 17.5), with the youngest being eight months old and the oldest being 203 months old. Of the 61 patients included in the study, 32 (52%) were male and 29 (48%) were female. The majority of patients (32 patients) were in the preschool age group (25-84 months). The primary diagnosis of 27 patients (44.3%) who underwent tracheostomy was neuromuscular diseases, and the most common indication for tracheostomy was prolonged intubation (24 patients, 39.3%). Concomitant chronic diseases were present in 54 patients (88.5%). Patients received mechanical ventilation support for an average of 47.34 days before tracheostomy. Early tracheostomy (0-21 days after initiation of mechanical ventilation) was performed on 14 patients, and late tracheostomy (21 days and later) was performed on 47 patients. Complications developed in nine patients (14.8%) in the perioperative period and in 19 patients (31.1%) in the postoperative period, while no complications developed in 39 patients (63.9%). Six patients (9.8%) were decannulated. Furthermore, 28 patients (45.9%) died. No tracheostomy-related mortality was documented. Conclusion: Despite most patients being of preschool age, having prolonged intubation prior to tracheostomy, and having accompanying chronic illnesses, tracheostomy remains a frequently used procedure in paediatric intensive care units due to its low complication rates, making it an essential intervention that facilitates discharge from paediatric intensive care.Öğe An Important Cause of Hyperbilirubinemia in a Newborn: Adrenal Hematoma(Galenos Yayincilik, 2015) Katar, Selahattin; Taskesen, Mustafa; Ozturkmen, Hatice AkayAim: In the present study, our aim was to investigate demographical, clinical characteristics and outcomes of management in seven patients with hyperbilirubinemia and adrenal hemorrhage detected in abdominal ultrasonography admitted with the complaint of icterus. Materials and Methods: In this retrospective study, we reviewed the medical records of seven patients with adrenal al hematoma diagnosed with abdominal ultrasonography. Physical examination findings, blood group types, direct Coombs test, total blood count, biochemical parameter, T4, TSH, G-6PD, CRP, total urine examination, PT, aPTT, treatment and duration of follow-up and abdominal ultrasonography findings were evaluated. Results: The presenting complaint was icterus. Two patients were females and five were males. All of the patients were born via vaginal delivery. One patient was born at home, six were born in hospital. On admission, physical examination findings revealed icterus in all cases, and there was abdominal mass in four of them. In the etiology of hyperbilirubinemia, blood group incompatibility (ABO, Rh or subgroup), hemolysis was not detected. All cases were diagnosed with adrenal hemorrhage. Adrenal hemorrhage was rightsided in 6 newborns, bilateral in 1. Adrenal insufficiency was not observed. Exchange transfusion was performed to 3 patients, and phototherapy was administered to 5. Resolution of adrenal hemorrhage was observed in ultrasonographic follow-up. Conclusion: In cases of hyperbilirubinemia of unknown etiology, adrenal hemorrhage must be kept in mind. Adrenal hematoma should also be considered in the differential diagnosis of hyperbilirubinemia. We recommend abdominal ultrasonography for further evaluation.Öğe Incidence and Risk Factors for Retinopathy in Premature Infants with Very Low Birth Weight, in the South-East Region, Turkey(Galenos Yayincilik, 2014) Katar, Selahattin; Taskesen, Mustafa; Ekmekciler, Belgin; Saka, GurayIntroduction: Retinopathy of prematurity (ROP) is the most common cause of childhood blindness. The risk of ROP is increased in premature infants with very low birth weights, as the most common risk factors for ROP are low birth weight and early periods of gestation. The aim of this study was to evaluate the risk factors and the incidence of ROP among premature infants weighing under 1500 g upon delivery. Materials and Methods: Between August 2010 and December 2012, 84 patients followed up in the neonatal intensive care unit who were under 32 weeks old at birth and under 1500 g at birth were included in this study. Patients were separated into two groups: those with retinopathy and those without. Then the risk factors were compared between groups. Results: Mean gestational age and birth weight of the patients in group 1 and group 2 were 27.86 +/- 2.0 weeks, 1,146.66 +/- 278.58 g and 29.08 +/- 1.96 weeks, 1,289.36 +/- 74.77 g, respectively. Retinopathy was detected in 44% of the patients and of them 7.1% were treated for severe retinopathy. We determined that early periods of gestation (p=0.007), low birth weight (p=0.007), being transported (p=0.01), intraventricular hemorrhage (p=0.04), prolonged ventilation (p=0.006), prolonged oxygen administration (p=0.01), and blood transfusion (p=0.01) were statistically significant risk factors in patients with retinopathy. Conclusions: ROP has been recognized as one of the most important causes of childhood blindness in the world. However blindness is preventable if patients are diagnosed early and treated properly. Thus, it is important to determine the risk factors for ROP.Öğe Naloxone use in a newborn with apnea due to tetrahydrozoline intoxication(Wiley-Blackwell, 2010) Katar, Selahattin; Taskesen, Mustafa; Okur, Nilufer[Abstract Not Available]Öğe Neurological presentations of nutritional vitamin B12 deficiency in 42 breastfed infants in Southeast Turkey(Tubitak Scientific & Technological Research Council Turkey, 2011) Taskesen, Mustafa; Yaramis, Ahmet; Katar, Selahattin; Gozu, Ayfer; Pirinccioglu, Ayfer Gozu; Soker, MuratAim: Nutritional vitamin B12 deficiency is common in developing and underdeveloped countries and has a wide variety of neurological presentations. The aim of this study was to evaluate the neurological characteristics and laboratory results of infants with vitamin B12 deficiency. Materials and methods: A total of 42 infants were included in this study. All patients were evaluated for clinical, physical, and neurological abnormalities, and an attempt was made to obtain short-term neurologic follow-up. Results: Of 42 patients, 24 (57%) were boys and 18 (43%) were girls. The average age at diagnosis was 13.04 +/- 5.68 months. Most of these infants were breastfed only and born from mothers with inadequate animal-derived protein consumption. Hypotonia (100%), anorexia (92.8%), neurodevelopmental (85.7%), and social (80.9%) retardation were the most present symptoms in all infants. Conclusion: Severe neurological and hematological findings may be found in children with vitamin B12 deficiency. Early diagnosis and treatment is crucial in cases of hematological complications and neurologic impairment. Neurologic impairment may be irreversible if the diagnosis is delayed beyond 12 months. We think that dietary management, such as nutritional support with vitamin B12 for the mothers during pregnancy and complementary food for infants, may prevent the neurological deficits and neurodevelopmental retardation.Öğe Novel Alu retrotransposon insertion leading to Alstrom syndrome(Springer, 2012) Taskesen, Mustafa; Collin, Gayle B.; Evsikov, Alexei V.; Guzel, Aysegul; Ozgul, R. Koksal; Marshall, Jan D.; Naggert, Juergen K.Alstrom syndrome is a clinically complex disorder characterized by childhood retinal degeneration leading to blindness, sensorineural hearing loss, obesity, type 2 diabetes mellitus, cardiomyopathy, systemic fibrosis, and pulmonary, hepatic, and renal failure. Alstrom syndrome is caused by recessively inherited mutations in the ALMS1 gene, which codes for a putative ciliary protein. Alstrom syndrome is characterized by extensive allelic heterogeneity, however, founder effects have been observed in some populations. To date, more than 100 causative ALMS1 mutations have been identified, mostly frameshift and non-sense alterations resulting in termination signals in ALMS1. Here, we report a complex Turkish kindred in which sequence analysis uncovered an insertion of a novel 333 basepair Alu Ya5 SINE retrotransposon in the ALMS1 coding sequence, a previously unrecognized mechanism underlying the mutations causing Alstrom syndrome. It is extraordinarily rare to encounter the insertion of an Alu retrotransposon in the coding sequence of a gene. The high frequency of the mutant ALMS1 allele in this isolated population suggests that this recent retrotransposition event spreads quickly, and may be used as a model to study the population dynamics of deleterious alleles in isolated communities.Öğe A rare cause of hyperbilirubinemia in a newborn: bilateral adrenal hematoma(Turkish J Pediatrics, 2008) Katar, Selahattin; Oeztuerkmen-Akay, Hatice; Devecioglu, Celal; Taskesen, MustafaHyperbilirubinemia is an important health problem in newborns. The most common causes are Rh and ABO incompatibility, hemolytic anemias, enzyme deficiencies, sepsis, hypothyroidism, pyloric stenosis and breast-milk jaundice. Adrenal hemorrhage is a rare cause of hyperbilirubinemia in the neonate. We present a six-day-old newborn with hyperbilirubinemia and suprarenal hematoma who was born at home without assistance of healthcare personnel. Adrenal hematoma should also be considered in the differential diagnosis of hyperbilirubinemia, particularly in newborns that experienced a difficult delivery.Öğe A RARE CAUSE OF POISONING IN CHILDHOOD: YELLOW PHOSPHORUS(Elsevier Science Inc, 2012) Taskesen, Mustafa; Adiguzel, SalihBackground: Yellow phosphorus poisoning is rare, but when it occurs, it may result in pathological changes in almost all organs of the body, especially the liver, heart, kidney, spleen, and brain, and it has a significant mortality rate. Objectives: This report presents two cases of poisoning by yellow phosphorus in children. Yellow phosphorus ingestion rarely has been reported among the pediatric population. Case Report: This report presents two cases of yellow phosphorus poisoning in children. The patients were admitted with upper abdominal pain, vomiting, lethargy, and respiratory distress. Laboratory testing revealed hepatotoxicity and coagulation disorder. Yellow phosphorus poisoning was treated with conservative therapy in both patients, and one patient died. Conclusion: Yellow phosphorus poisoning is a rare clinical entity and should be considered a dangerous toxic ingestion in children. (C) 2012 Elsevier Inc.Öğe A rare cause of severe periorbital edema and dermonecrotic ulcer of the eyelid in a child: Brown recluse spider bite(Turkish J Pediatrics, 2011) Taskesen, Mustafa; Akdeniz, Sedat; Tas, Taskin; Keklikci, Ugur; Tas, Mehmet AliSpider bites are a worldwide problem. Brown recluse spider bites can lead to severe local or systemic clinical effects, such as edema, necrotic ulcer, rashes, fever, chills, nausea, vomiting, malaise, arthralgia, myalgia, hemolysis, leukocytosis, disseminated intravascular coagulation, renal failure, and death. Eyelid bites from brown recluse spiders are rare. We report a child with severe facial edema and a dermonecrotic ulcer on the eyelid. Upon laboratory examination, leukocytosis with a significant left shift was detected. The patient was treated with antibiotics, systemic corticosteroid and conservative therapy that included saline compresses and ocular lubrication. No surgical excision was required. Vision was not impaired. A dermonecrotic ulcer is a severe complication of brown recluse spider bites. Since the diagnosis is difficult, clinical and epidemiological findings and a detailed history are important for an accurate diagnosis.Öğe A retrospective investigation of clinical and laboratory findings in children with acute rheumatic fever, reactivation and compliance with prophylaxis(Turkish Soc Cardiology, 2012) Pirinccioglu, Ayfer Gozu; Alyan, Omer; Kangin, Murat; Taskesen, Mustafa; Fidan, Mucahit; Mermutoglu, Nihat; Sen, VelatObjectives: We aimed to retrospectively investigate the patients with acute rheumatic fever (ARF) by evaluating their clinic and laboratory properties, echocardiographic findings as well as the reactivation and the compliance to penicillin prophylaxis. Study design: The study involved 255 patients (143 boys, 112 girls; mean age 10.1 +/- 2.7 years) with ARF. Their sex, age, clinic and laboratory properties, echocardiographic findings, the reactivation and the compliance to penicillin prophylaxis were recorded. Results: Patients spent 13.3 +/- 4.3 days in the hospital, and 94 had a history of ARE. Arthritis was found in 233 patients, carditis in 166. Sydenham's chorea in 14, subcutaneous nodule in 2, and arthritis-carditis in 151 patients. Erythema marjinatum was not found in any patient. Arthralgia (n=15) and fever (n=246) were found in patients. Throat culture was positive in 94 patients and anti-streptolysin-O titers were high in 124 patients. Mitral involvement was found in 205 patients while the combination of mitral and aortic valve involvement were observed in 118 patients. Conclusion: ARF still continues to be a major public health problem in our country. A bad prognosis may be prevented by early diagnosis and treatment. The importance of appropriate prophylaxis should also be emphasized.Öğe Role and Clinical Significance of Plasma N-Terminal Brain Natriuretic Peptide Measurement in Children with Brain Edema(Georg Thieme Verlag Kg, 2016) Taskesen, Mustafa; Celik, Hasan; Yaramis, Ahmet; Tas, Mehmet A.Objective Brain natriuretic peptide (BNP) is a potent natriuretic and vasodilator factor. BNP plasma concentrations were found to be elevated in patients with brain edema. The purpose of the present study is to evaluate the relationship between plasma NT-proBNP concentration and the presence of brain edema in patients with intracranial pathology. Materials and Methods The plasma NT-proBNP levels of 50 patients and 25 healthy subjects were measured. The NT-proBNP levels of the patient group were measured during admission and after 7 days of treatment. Results NT-proBNP plasma concentrations were found to be significantly higher in the patient group with brain edema than in the control group (p < 0.005). There were no significant differences in the NT-proBNP plasma concentrations between patients with intracranial pathology without brain edema and the control group (p > 0.005). NT-proBNP plasma concentrations were found to be significantly higher in patients with brain edema as compared with patients without brain edema before treatment (p < 0.005). Conclusion These results suggest that excessive secretion of plasma NT-proBNP is related to brain edema. Plasma NT-proBNP levels may serve as a marker to guide the early-diagnostic and therapeutic management in children with brain edema. Further studies are required to evaluate the role of BNP in brain edema pathophysiology.Öğe Typhoid fever complicated by multiple organ involvement in a child(Dicle Üniversitesi Tıp Fakültesi, 2008) Taskesen, Mustafa; Katar, Selahattin; Ecer, Sultan; Kervancıoglu, Mehmet; Sevinc, ŞeyhmusA 12-year old girl was admitted to our clinic because of fever, headache, diarrhea and weakness for 10 days. Dyspne, tachycardia, hypotension, fever and letargy were determined in physical examination. The levels of urea, creatinine, aspartate aminotransferase, alanine aminotransferase were found to be increased. In echocardiography, myocardial dysfunction and low systolic functions were detected. Blood culture was positive for S.typhi. We report multiple organ involvement in a patient with typhoid fever and review the literature.Öğe Underwater Drainage of Pneumothorax by Angiocath Versus Thorax Tube in Newborn Patients(Galenos Yayincilik, 2019) Katar, Selahattin; Taskesen, Mustafayyy INTRODUCTION: Pneumothorax is a major cause of respiratory distress and associated with increased mortality and morbidity in newborn patients. The aim of this article was to emphasize the usability of underwater seal drainage with branule, which is a simple and non-aggressive method, in the treatment of newborn patients with pneumothorax. METHODS: The medical records of patients who were hospitalized in the neonatal intensive care unit with a diagnosis of pneumothorax between August 2010 and November 2015 were investigated retrospectively. RESULTS: A total of 1017 patients were hospitalized in our neonatal intensive care unit between August 2010 and November 2015. Of them, 1.6% (n:17) had pneumothorax. The mean body weight was 2314.7 +/- 1023.4 g (730-3600 g) and gestational age was 34.0 +/- 5.4 weeks (24-40 weeks). Two patients had bilateral pneumothorax, one patient had left-sided pneumothorax, and 14 patients had right-sided pneumothorax. In three patients, pneumothorax spontaneously resolved without any procedure. Four patients underwent tube thoracostomy, and 10 patients were treated by underwater seal drainage with branule. In one of the patients who underwent tube thoracostomy, reintervention was performed because of the tube dislocation. The primary disease which caused pneumotorax was diagnosed as respiratory distress syndrome in nine patients, asphyxia-meconium aspiration in five patients, and transient tachypnea of the newborn in three patients. Two patients died. DISCUSSION and CONCLUSION: In newborn patients with pneumothorax, underwater drainage with branule may be used by physicians experienced in neonatal care as a quick and easy procedure when a pediatric surgeon is not available to perform the relatively more difficult and agressive option of thorax tube insertion.