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Öğe ANGIOTENSIN-CONVERTING ENZYME AND ANGIOTENSIN II TYPE 1 RECEPTOR GENE POLYMORPHISMS IN CHILDREN WITH SUBACUTE SCLEROSING PANENCEPHALITIS(Wiley-Blackwell, 2015) Tasdemir, N.[Abstract Not Available]Öğe Apolipoprotein E genotype in patients with cerebrovascular diseases and its effect on the disease outcome(Wiley-Blackwell, 2010) Tamam, Y.; Tasdemir, N.; Toprak, R.; Tamam, B.; Iltumur, K.[Abstract Not Available]Öğe Association of apolipoprotein E genotype and cerebrovascular disease risk factors in a Turkish population(Elsevier Science Bv, 2009) Tasdemir, N.; Tamam, Y.; Toprak, R.; Tamam, B.; Tasdemir, M. S.[Abstract Not Available]Öğe Association of apolipoprotein E genotypes with prognosis in multiple sclerosis(Verduci Publisher, 2011) Tamam, Y.; Tasdemir, N.; Yalman, M.; Tamam, B.Background: Although the association between apolipoprotein E (APOE) genetic polymorphisms and multiple sclerosis (MS), has been debated, the presence of the epsilon 4 allele has been associated with an aggressive disease progression. Objectives: Present study aimed to investigate whether or not the APOE allele has an impact on disease progression in patients with MS. The study investigated the presence and clinical correlations of certain APOE genotypes in patients with MS. Materials and Methods: Fifty patients were enrolled in the study. APOE genotype was determined by polymerase chain reaction (PCR), the total apoE level was established using the nephelometric method. Expanded Disability Status Scale (EDSS) scores were also established. The progression index (PI) was calculated as the EDSS score/disease duration. Results: The most common APOE genotype in MS patients was epsilon 3/epsilon 3 (82.0%). Male patients with MS were significantly more likely to have epsilon 4, and at baseline, the disease duration was shorter, the EDSS scores were higher, the serum total ApoE levels were lower, and the PI was significantly higher. The MS onset age, clinical types, EDSS scores, and PI were not significantly correlated with epsilon 4 allele-positive. Visual onset and sensory onset are good prognostic factors. There were no patients with visual onset and few patients with sensory onset in the epsilon 4-positive group. Conclusions: The present study established male patients with MS had a higher APOE epsilon 4 frequency and disease severity, but were likely to have lower serum ApoE levels. An additional study is needed with a larger sample to include all genotypes.Öğe Childhood dermatomyositis. A case report: An atypical presentation(Blackwell Publishing, 2006) Tasdemir, N.; Tasdemir, M. S.; Akcicek, A.[Abstract Not Available]Öğe Congenital end-plate acetylcholinesterase deficiency and the effect of ephedrine on clinical findings, lung functions and nocturnal parameters(Pergamon-Elsevier Science Ltd, 2009) Kiyan, E.; Kara, B.; Oflazer, P. Serdaroglu; Parman, Y.; Tasdemir, N.; Deymeer, F.; Engel, A. G.[Abstract Not Available]Öğe IL17 and IL-23 levels have been determined patients who have RR- serum MS(Elsevier Science Bv, 2017) Tasdemir, N.[Abstract Not Available]Öğe The levels of serum cytokine in intrahemispheric haemorrhagic patients(Blackwell Publishing, 2006) Tasdemir, N.; Karaca, E. E.; Tasdemir, M. S.[Abstract Not Available]Öğe Multiple sclerosis: Relationships between cytokines, visual evoked potentials and disability(Blackwell Publishing, 2006) Tasdemir, N.; Karaca, E. E.; Ece, A.; Tasdemir, M. S.[Abstract Not Available]Öğe Orbital cellulitis of fatal course applying with headache complaint: A case report(Elsevier Science Bv, 2017) Tasdemir, N.[Abstract Not Available]Öğe Peripheral neuropathy after burn injury(Verduci Publisher, 2013) Tamam, Y.; Tamam, C.; Tamam, B.; Ustundag, M.; Orak, M.; Tasdemir, N.OBJECTIVES: Peripheral neuropathy is a well-documented disabling sequela of major burn injury. These lesions are associated with both thermal and electrical injuries that may be frequently undiagnosed or overlooked in clinical settings. The purpose of this study was to evaluate the prevalence of burn-related neuropathy in our database and to investigate the clinical correlates for both mononeuropathy and generalized peripheral polyneuropathy. PATIENTS AND METHODS: Out of 648 burn patients, admitted to our clinic forty-seven burn patients with the diagnosis of peripheral neuropathy were evaluated retrospectively. The demographic and clinical data collected were gender, age, degree, site and percent surface area of burn, type of burn, and the results of electrodiagnostic examination, including electromyography and nerve conduction assessments and associated pathology if existed. RESULTS: Peripheral neuropathy is the most frequent disabling neuromuscular complication of burn, that may be undiagnosed or overlooked. In current study, peripheral neuropathy associated with burn all of our patients were identified by electrodiagnostic study. After treatment in Burn Unit, clinical and electrodiagnostic studies were applied. Motor and sensory distal latencies were prolonged and sensory nerve action potentials reduced in amplitude. CONCLUSIONS: The findings of our study have shown that polyneuropathies and axonal neuropathy were more frequent than mononeuropathy and demyelination.Öğe Serum CHI3LI and CHI3L2 levels in detecting disease activity and prognosis in multiple sclerosis patients(Elsevier, 2019) Tasdemir, N.; Degirmenci, B.[Abstract Not Available]Öğe Serum IL-27, IL-23 and IL-35 Levels in Neuromyelitis Optica Spectrum Disorders with Aquaporin-4 and Multiple Sclerosis(Sage Publications Ltd, 2018) Idiman, Egemen; Kaya, D.; Hasankoyoglu, O.; Keskin, A. O.; Tasdemir, N.; Altun, Z.[Abstract Not Available]
