Yazar "Tas, A." seçeneğine göre listele

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    Fluid resuscitation in the treatment of uncontrolled hemorrhagic shock
    (Springer Wien, 2008) Yagmur, Y.; Ozturk, H.; Orak, M.; Tas, A.; Guneli, E.
    Background: We evaluated the effect of continuous fluid resuscitation on the hemodynamic response and survival following massive splenic injury (MSI) in rats. Methods: Uncontrolled hemorrhagic shock was produced in 70 rats by sharp transaction. The animals were randomized into 7 groups: group 1 (n = 10), sham-operated; group 2 (n = 10), MSI was untreated and splenectomy was performed after 45 min; group 3 (n = 10), MSI treated after 15 min with 7.5 ml/kg/h of 7.5% NaCl (HTS-7.5) and splenectomy after 45 min; group 4 (n = 10), MSI treated with 35 mL/kg/h Ringers lactate (RL) solution (RL-35) and splenectomy; group 5 (n = 10), MSI treated with 70 mL/kg/h RL (RL-70) and splenectomy, group 6 (n=10), NISI treated with 35mL/kg/h of 0.9% NaCl (NaCl-35) and splenectomy; and group 7 (n=10), MSI treated with 70mL/kg/h of 0.9% NaCl (NaCl-70) and splenectomy. Results: Small and high volume ringer lactate (RL-35, RL-70) infusion increased MAP, pulse rate, and hematocrit level compared to untreated group (p<0.001); however, best response was inquired by RL-35. TBL with RL-35 (22% of blood volume) was less than RL-70 and other groups (p<0.01). High rate of early mortality (33.4% at 30min) with HTS infusion was noticed. TBL was moderately increased in NaCl-70 (32% of blood volume) compared to NaCl-35 (30% of blood volume). Survival time was better with RL-35 and RL-70 at 60 min and 120min, respectively, compared to other groups (p < 0.05). Conclusions: In conclusion, continuous infusion of HTS, RL-70, NaCl-35 and NaCl-70 following massive splenic injury in uncontrolled hemorrhagic shock resulted in a significant increase in intra-abdominal bleeding compared to lower dose RL-35 and greatest survival time was noticed with RL-35 and RL-70 at 60 and 120 min, respectively.
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    Öğe
    Post-COVID syndrome and pain perception in outpatients with COVID-19
    (Verduci Publisher, 2023) Tas, A.; Baloglu, M.
    OBJECTIVE: This study aimed to investigate the prevalence of pain symptoms in outpatients with COVID-19 and to analyze the relationship between pain-related, psychological, and cognitive variables in patients with ongoing pain complaints after COVID-19.PATIENTS AND METHODS: 79 people participated in the research. The focus was on completed demographics (such as age, height, and weight), pain-related (duration and intensity of pain), Modified Medical Research Coun- cil (MMRC) Dyspnea Score, and visual analogue scale (VAS) variables.RESULTS: Significant changes were found in some of the post-COVID symptoms after 3 months. From the 3rd month, the VAS pain scale score, EQ5D-3L quality of life score, and VAS score obtained from EQ-5D-3L quality of life scale, sitting scores decreased compared to the first measurements. Muscle strength, moderate activity, walking, and total scores increased from the third month.CONCLUSIONS: We suggest physical pain and inactivity symptoms in patients with COVID regressed in the 3rd month.
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    Öğe
    Treatment and outcomes of patients with metastatic spinal cord compression: a double-center study
    (Verduci Publisher, 2023) Aycan, A.; Eren, B.; Tas, A.; Celik, S.; Guzey, F. Karagoz; Kuyumcu, F.; Akyol, M. E.
    OBJECTIVE: Spinal metastases may only affect the bone tissue and result in spi-nal instability or may additionally result in epi-dural compression, leading to neurological defi-cits. Surgery has emerged as a popular method in treating metastatic epidural spinal cord com-pression (MESCC) due to the advances in surgical techniques and instrumentation. In this study, we evaluated patients with MESCC regarding neuro-logical status, pain status, and survival rates, and presented our experience managing MESCC.PATIENTS AND METHODS: Clinical and ra-diographic records of 53 patients diagnosed with MESCC between January 2011 and March 2017 were retrospectively evaluated. The study included patients with a pathological diagnosis of primary cancer, those who complained of spi-nal metastasis, and those who had indications of MESCC on Magnetic Resonance Imaging (MRI). Bone structure and spinal stability were evaluat-ed using assessed Computed Tomography (CT), and metastatic spread was considered using as-sessed Positron Emission Tomography (PET) in suitable cases. For each patient, the presence of a tumor compressing the spinal cord, age, gen-der, preoperative, and postoperative American Spinal Injury Association scores (ASIA), Toku-hashi prognostic score (TPS), affected spinal segment, pathological diagnosis, preoperative, and postoperative Visual Analog Scale (VAS), the status of spinal stability, follow-up period, and complications were evaluated.RESULTS: Forty-five patients (82.2% of them were women) underwent surgery with a mean age of 58.29 & PLUSMN; 15.14 years. The most frequent type of primary tumor was multiple myeloma (33.9%), followed by lung (24.6%), gastric (7.5%), and prostate (5.7%). The most common site of metastasis was the thoracic region (43.4%), fol-lowed by lumbar (24.5%), multiple (24.5%), and cervical (5.7%). The analysis indicated that a sig-nificant difference was found between the sur-vival rates of the TPS categories.CONCLUSIONS: Common symptoms of MES-CC include spinal pain and neurological defi-cit below the level of the injury. Prompt surgi-cal treatment followed by oncological treatment leads to significant neurological recovery, more prolonged survival, pain relief, and improved quality of life in patients with a short survival time. Oncological treatments, including radio-therapy (RT), should be recommended after sur-gical treatment.