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Öğe Peripheral neuropathy after burn injury.(2013) Tamam Y.; Tamam C.; Tamam B.; Ustundag M.; Orak M.; Tasdemir N.Peripheral neuropathy is a well-documented disabling sequela of major burn injury. These lesions are associated with both thermal and electrical injuries that may be frequently undiagnosed or overlooked in clinical settings. The purpose of this study was to evaluate the prevalence of burn-related neuropathy in our database and to investigate the clinical correlates for both mononeuropathy and generalized peripheral polyneuropathy. Out of 648 burn patients, admitted to our clinic forty-seven burn patients with the diagnosis of peripheral neuropathy were evaluated retrospectively. The demographic and clinical data collected were gender, age, degree, site and percent surface area of burn, type of burn, and the results of electrodiagnostic examination, including electromyography and nerve conduction assessments and associated pathology if existed. Peripheral neuropathy is the most frequent disabling neuromuscular complication of burn, that may be undiagnosed or overlooked. In current study, peripheral neuropathy associated with burn all of our patients were identified by electrodiagnostic study. After treatment in Burn Unit, clinical and electrodiagnostic studies were applied. Motor and sensory distal latencies were prolonged and sensory nerve action potentials reduced in amplitude. The findings of our study have shown that polyneuropathies and axonal neuropathy were more frequent than mononeuropathy and demyelination.Öğe Plasma D-Dimer levels in acute ischemic stroke: Association with mortality, stroke type and prognosis(2010) Üstündağ M.; Orak M.; Güloglu C.; Tamam Y.; Sayhan M.B.• Objective: The purpose of this study is to examine the correlation between mortality, stroke sub-types, neurological disability and D-Dimer values measured before a specific treatment is given to patients in the emergency department. • Material and Method: In the first 24 hours after stroke symptoms started and before anticoagulant treatment started, the serum D-Dimer levels of every patient were examined. The stroke sub-type of every patient was determined according to TOAST criteria and clinical classification was made according to the Oxfordshire Community Stroke Project (OCSP). The Rankin scale was used to determine the neurological disability of the surviving patients. • Results: Ninety one patients were included in the study. There was a significant difference between the D-Dimer levels of patients who died and who survived (4.50+2.80 and 1.39+1.36 ng/ml respectively, p=0.003). According to the TOAST criteria, average D-dimer levels of cardioembolic and atherothrombotic stroke patients were higher than the control group. (4.35±3.03/ 3.11±1.69 and 0.43±0.26 respectively, p=0.000). According to OCSP classification, average D-dimer levels of patients with total anterior circulation infract (TOCI) and partial anterior circulation infract (PACI) were higher than the control group. (3.67±2.14, 4±3.03 and 0.43±0.26, respectively, p=0.000). The evaluation of surviving stroke patients in terms of neurological disability revealed that average D-dimer levels of patients with serious neurological disability Rankin score=3-5) were higher than patients with slight neurological disability (Rankin score=0 and Rankin score=1-2), (2.85±1.69; 0.79±0.56; 0.81±0.44 respectively, p=0.000). • Conclusion: We reached the conclusion that D-dimer levels in the acute period can be a leading factor for clinicians in predicting the direct results of cerebral infarct and deciding the type of treatment.Öğe The relationship between musekna index and stroke severity in patients with acute ischemic stroke(Ondokuz Mayis Universitesi, 2020) Ozturk U.; Ozturk O.; Tamam Y.Acute stroke is an important cause of morbidity and mortality. Prediction tools are especially helpful in this situation in guiding for medical treatment decision. It is found that prognostic index is predictor of mortality and heart failure in patients with ischemic heart failure implanted with an ICD, the prognostic index (PI) being built according to the formula: 120 - age + mean 24 h systolic blood pressure - (creatinine * 10). However, a mean 24 h systolic blood pressure calculation is not clinically easy. Therefore, we propose a new modified prognostic index (Musekna Index). Musekna Index (MI) was calculated as “120 - age + mean arterial pressure - (creatinine * 10)”. In this study, we aimed to investigate the relationship between MI and stroke severity in patients with acute ischemic stroke. This cross-sectional study included 162 patients (males, 64; females, 98; 67 ± 15 years) with acute ischemic stroke. Patients were divided into two groups based on the calculated National Institutes of Health Stroke Scale (NIHSS) score (Group 1, NIHSS score < 16; Group 2, NIHSS score ? 16). Demographic, clinical, and laboratory data for all patients were collected. Musekna Index (Modified Prognostic Index) was calculated as “120 - age + mean arterial pressure - (creatinine * 10)”. MI index was calculated admission to the neurology care unit. Echocardiographic examinations were performed using the parasternal longitudinal axis and apical 4-chamber windows in accordance with the recommendations of the American Echocardiography Committee. There were no significant differences among the demographic parameters of patients. MI was significantly higher in Group 1 patients than in Group 2 patients (139±15.6 vs 132±13.7, p=0.028). Our results suggest that MI is associated with stroke severity on admission in patients with acute ischemic stroke. © 2020 OMU