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Öğe Apolipoprotein E genotype in patients with cerebrovascular diseases and its effect on the disease outcome(Wiley-Blackwell, 2010) Tamam, Y.; Tasdemir, N.; Toprak, R.; Tamam, B.; Iltumur, K.[Abstract Not Available]Öğe Association of apolipoprotein E genotype and cerebrovascular disease risk factors in a Turkish population(Elsevier Science Bv, 2009) Tasdemir, N.; Tamam, Y.; Toprak, R.; Tamam, B.; Tasdemir, M. S.[Abstract Not Available]Öğe Association of apolipoprotein E genotypes with prognosis in multiple sclerosis(Verduci Publisher, 2011) Tamam, Y.; Tasdemir, N.; Yalman, M.; Tamam, B.Background: Although the association between apolipoprotein E (APOE) genetic polymorphisms and multiple sclerosis (MS), has been debated, the presence of the epsilon 4 allele has been associated with an aggressive disease progression. Objectives: Present study aimed to investigate whether or not the APOE allele has an impact on disease progression in patients with MS. The study investigated the presence and clinical correlations of certain APOE genotypes in patients with MS. Materials and Methods: Fifty patients were enrolled in the study. APOE genotype was determined by polymerase chain reaction (PCR), the total apoE level was established using the nephelometric method. Expanded Disability Status Scale (EDSS) scores were also established. The progression index (PI) was calculated as the EDSS score/disease duration. Results: The most common APOE genotype in MS patients was epsilon 3/epsilon 3 (82.0%). Male patients with MS were significantly more likely to have epsilon 4, and at baseline, the disease duration was shorter, the EDSS scores were higher, the serum total ApoE levels were lower, and the PI was significantly higher. The MS onset age, clinical types, EDSS scores, and PI were not significantly correlated with epsilon 4 allele-positive. Visual onset and sensory onset are good prognostic factors. There were no patients with visual onset and few patients with sensory onset in the epsilon 4-positive group. Conclusions: The present study established male patients with MS had a higher APOE epsilon 4 frequency and disease severity, but were likely to have lower serum ApoE levels. An additional study is needed with a larger sample to include all genotypes.Öğe Burden of alzheimer type dementia on caregivers(Elsevier Science Bv, 2015) Tamam, Y.; Oncel, O.[Abstract Not Available]Öğe Comparision computerized tomography and brain SPECT in patients with acute ischemic stroke diagnosis(Springer, 2009) Kaya, H.; Altunci, G. Kaya; Tamam, Y.; Karahan, C. Can[Abstract Not Available]Öğe The efficiency of low level laser therapy in carpal tunnel syndrome(Wiley-Blackwell, 2012) Tamam, Y.; Tanrikulu, T.; Oncel, O.; Turgut, S.; Aruk, T.[Abstract Not Available]Öğe Evaluation of autonomic nervous system in acute stroke through the assessments of heart rate variability and catecholamine levels(Springer Heidelberg, 2014) Akil, E.; Akil, M. A.; Kaplan, I.; Bilik, M. Z.; Tamam, Y.[Abstract Not Available]Öğe Evaluation of autonomic nervous system in acute stroke through the assessments of heart rate variability and catecholamine levels(Wiley-Blackwell, 2014) Akil, E.; Akil, M. A.; Kaplan, I.; Bilik, M. Z.; Tamam, Y.[Abstract Not Available]Öğe Evaluation of Rivastigmine Therapy with Tc99m HMPAO Brain Perfusion SPECT and MMSE Scores in Alzheimer's Disease(Springer, 2005) Cerci, S. S.; Kaya, H.; Yildiz, M.; Tamam, Y.; Arslan, S.[Abstract Not Available]Öğe Evaluation of sexuality in stroke patients(Elsevier Science Bv, 2009) Tamam, Y.; Tamam, L.; Akil, E.; Yasan, A.; Tamam, B.[Abstract Not Available]Öğe Frequency of cognitive impairment in relapsing-remitting multiple sclerosis patients in Turkey and affecting factors(Sage Publications Ltd, 2017) Ozakbas, S.; Turkoglu, R.; Tamam, Y.; Terzi, M.; Taskapilioglu, O.; Yucesan, C.; Limoncu, H.[Abstract Not Available]Öğe Peripheral lidocaine injection (neural therapy) in the treatment of migraine in pregnancy(Elsevier Science Bv, 2017) Tamam, Y.; Tamam, C.; Goksel, A.; Tamam, B.; Nazlikul, H.[Abstract Not Available]Öğe Peripheral neuropathy after burn injury(Verduci Publisher, 2013) Tamam, Y.; Tamam, C.; Tamam, B.; Ustundag, M.; Orak, M.; Tasdemir, N.OBJECTIVES: Peripheral neuropathy is a well-documented disabling sequela of major burn injury. These lesions are associated with both thermal and electrical injuries that may be frequently undiagnosed or overlooked in clinical settings. The purpose of this study was to evaluate the prevalence of burn-related neuropathy in our database and to investigate the clinical correlates for both mononeuropathy and generalized peripheral polyneuropathy. PATIENTS AND METHODS: Out of 648 burn patients, admitted to our clinic forty-seven burn patients with the diagnosis of peripheral neuropathy were evaluated retrospectively. The demographic and clinical data collected were gender, age, degree, site and percent surface area of burn, type of burn, and the results of electrodiagnostic examination, including electromyography and nerve conduction assessments and associated pathology if existed. RESULTS: Peripheral neuropathy is the most frequent disabling neuromuscular complication of burn, that may be undiagnosed or overlooked. In current study, peripheral neuropathy associated with burn all of our patients were identified by electrodiagnostic study. After treatment in Burn Unit, clinical and electrodiagnostic studies were applied. Motor and sensory distal latencies were prolonged and sensory nerve action potentials reduced in amplitude. CONCLUSIONS: The findings of our study have shown that polyneuropathies and axonal neuropathy were more frequent than mononeuropathy and demyelination.Öğe Post-stroke sexual functioning in first stroke patients(Wiley, 2008) Tamam, Y.; Tamam, L.; Akil, E.; Yasan, A.; Tamam, B.Background and purpose: Although physical problems after stroke have been well studied, there is little information on one of the crucial aspects of the quality of life of those patients, namely sexual functioning and satisfaction. The aim of this study was to assess the impact of stroke on sexual functioning in a stable cohort of Turkish stroke patients with mild or no disability and to assess the relationship between post-stroke sexuality and a number of socio-demographic, clinical and laboratory variables. Methods: The sexual functioning of 103 Turkish stroke patients with no disability or mild disability was assessed in two consecutive interviews along with clinical and sociodemographic features. NIH stroke, Glasgow coma, Barthel, and Rankin scales were also applied to assess neurologic status and disability. Results: Most of the patients were male (61%) and illiterate (70%). There was a significant difference between the baseline and post-stroke frequency of sexual activity of the patients. The differences between baseline and post-stroke vaginal lubrication, orgasms and satisfaction were all statistically significant. This latter difference was significant for both genders. Frequency of coitus both prior to and after the stroke was significantly different between males and females. Erection and ejaculation of the males was significantly affected by the stroke, and lubrication and orgasm was affected in the females. Interestingly, fear of recurrent stroke did not differ between genders. Discussion and Conclusion: Our study has shown that Turkish stroke survivors have sexual health needs during the rehabilitation process, though this has not been addressed previously. Sexual health needs seem to be affected by cultural factors and biases.Öğe Prevalence of dementia one year after stroke(Elsevier Science Bv, 2015) Tamam, B.; Tamam, Y.[Abstract Not Available]Öğe Prognostic value of adipokines in multiple sclerosis(Wiley, 2017) Tuzun, E.; Duzel, B.; Turkoglu, R.; Tamam, Y.[Abstract Not Available]Öğe Relationship between nitric oxide, asymmetric dimethylarginine levels and diabetic neuropathy(Springer Heidelberg, 2013) Tamam, Y.; Uzar, E.; Evliyaoglu, O.; Tay, A.; Kilinc, F.; Cevik, M.[Abstract Not Available]Öğe The role of serum ferritin, pro-brain natriuretic peptide and homocysteine levels in determining ischaemic stroke subtype, severity and mortality(Medcom Ltd, 2010) Ustundag, M.; Orak, M.; Guloglu, C.; Ozturk, E.; Tamam, Y.; Kale, E.Background: In ischaemic stroke, there are many biochemical and immunological reactions secondary to a reduced cerebral blood flow. The purpose of this Study is to investigate the correlation between stroke subtype, stroke severity, mortality, and serum ferritin, pro-brain natriuretic peptide (pro-BNP), homocysteine values before a specific treatment is given to stroke patients in the emergency department. Methods: Consecutive acute ischaemic stroke patients admitted between December 2007 and April 2008 were enrolled into the study. Serum ferritin, pro-BNP and homocysteine levels were Studied before specific treatment was carried Out. Stroke subtypes were determined according to the Trial of Org 10172 in Acute Stroke Treatment (TOAST) and Oxfordshire Community Stroke Project (OCSP) criteria. The severity of stroke was determined by the National Institutes of Health Stroke Scale (NIHSS). Fifteen healthy individuals who matched the Study group in terms of sex and age were chosen as control. Results: Ninety-two patients were included in the study. There was a significant difference in the serum ferritin, pro-BNP and homocysteine levels between patients who died and those who survived (p=0.013, p<0.001 and p=0.003 respectively). Serum ferritin, pro-BNP and homocysteine levels were higher in all stroke subtypes than in the control group. Comparing among stroke subtypes, only serum pro-BNP levels were higher in the cardioembolic stroke group than in the atherothrombotic stroke and lacunar stroke groups (p=0.003 and p<0.001 respectively); and only serum pro-BNP levels were higher in the total anterior circulation infarct group than in the posterior circulation infarct and lacunar infarct groups (p=0.010 and p=0.017 respectively). Pro-BNP levels were significantly higher in patients with NIHSS score >15 than NIHSS=8-15 and NIHSS=1-7 (p=0.016 and p<0.001 respectively). Conclusion: Ferritin, pro-BNP and homocysteine levels were raised in acute ischaemic stroke patients. However, only serum pro-BNP level is clinically useful in predicting stroke subtype, severity and mortality that could provide an insight to the choice of treatment. (Hong Xong j.emerg.med. 2010;17:13-21)Öğe The Role of Serum Osteoprotegerin and S-100 Protein Levels in Patients with Acute Ischaemic Stroke: Determination of Stroke Subtype, Severity and Mortality(Field House Publishing Llp, 2011) Ustundag, M.; Orak, M.; Guloglu, C.; Tamam, Y.; Sayhan, M. B.; Kale, E.This study investigated correlations between mortality, stroke subtype and stroke severity with serum osteoprotegerin (OPG) and S-100 protein levels prior to the treatment of patients admitted to the emergency department and diagnosed with ischaemic stroke. Pretreatment serum samples were collected from patients (n = 90) to determine OPG and S-100 protein levels. Age- and sex-matched healthy individuals (n = 16) served as controls. Compared with controls, OPG and S-100 protein levels were significantly higher in the cardioembolic and atherothrombotic stroke groups. Within the stroke group, OPG levels were significantly higher in the cardioembolic and atherothrombotic stroke groups compared with the transient ischaemic attack (TIA) group. S-100 protein levels were significantly higher in the atherothrombotic stroke group than in the lacunar stroke and TIA groups, and in the cardioembolic stroke group compared with the lacunar stroke group. Serum OPG and S-100 protein levels were significantly higher in patients who died compared with survivors. In predicting stroke subtype and severity, although both OPG and S-100 protein levels were indicators, S-100 protein was more valuable for mortality prediction.Öğe SENSITIVITY AND SPECIFICITY OF TERMINAL LATENCY INDEX AND RESIDUAL LATENCY IN THE DIAGNOSIS OF CARPAL TUNNEL SYNDROME(Wiley-Blackwell, 2011) Uzar, E.; Tamam, Y.; Acar, A.; Yucel, Y.; Palanci, Y.; Cansever, S.; Cevik, M. U.[Abstract Not Available]
