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Öğe Apolipoprotein E genotype in patients with cerebrovascular diseases and its effect on the disease outcome(Wiley-Blackwell, 2010) Tamam, Y.; Tasdemir, N.; Toprak, R.; Tamam, B.; Iltumur, K.[Abstract Not Available]Öğe Association of apolipoprotein E genotype and cerebrovascular disease risk factors in a Turkish population(Elsevier Science Bv, 2009) Tasdemir, N.; Tamam, Y.; Toprak, R.; Tamam, B.; Tasdemir, M. S.[Abstract Not Available]Öğe Association of apolipoprotein E genotypes with prognosis in multiple sclerosis(Verduci Publisher, 2011) Tamam, Y.; Tasdemir, N.; Yalman, M.; Tamam, B.Background: Although the association between apolipoprotein E (APOE) genetic polymorphisms and multiple sclerosis (MS), has been debated, the presence of the epsilon 4 allele has been associated with an aggressive disease progression. Objectives: Present study aimed to investigate whether or not the APOE allele has an impact on disease progression in patients with MS. The study investigated the presence and clinical correlations of certain APOE genotypes in patients with MS. Materials and Methods: Fifty patients were enrolled in the study. APOE genotype was determined by polymerase chain reaction (PCR), the total apoE level was established using the nephelometric method. Expanded Disability Status Scale (EDSS) scores were also established. The progression index (PI) was calculated as the EDSS score/disease duration. Results: The most common APOE genotype in MS patients was epsilon 3/epsilon 3 (82.0%). Male patients with MS were significantly more likely to have epsilon 4, and at baseline, the disease duration was shorter, the EDSS scores were higher, the serum total ApoE levels were lower, and the PI was significantly higher. The MS onset age, clinical types, EDSS scores, and PI were not significantly correlated with epsilon 4 allele-positive. Visual onset and sensory onset are good prognostic factors. There were no patients with visual onset and few patients with sensory onset in the epsilon 4-positive group. Conclusions: The present study established male patients with MS had a higher APOE epsilon 4 frequency and disease severity, but were likely to have lower serum ApoE levels. An additional study is needed with a larger sample to include all genotypes.Öğe Evaluation of sexuality in stroke patients(Elsevier Science Bv, 2009) Tamam, Y.; Tamam, L.; Akil, E.; Yasan, A.; Tamam, B.[Abstract Not Available]Öğe Peripheral lidocaine injection (neural therapy) in the treatment of migraine in pregnancy(Elsevier Science Bv, 2017) Tamam, Y.; Tamam, C.; Goksel, A.; Tamam, B.; Nazlikul, H.[Abstract Not Available]Öğe Peripheral neuropathy after burn injury(Verduci Publisher, 2013) Tamam, Y.; Tamam, C.; Tamam, B.; Ustundag, M.; Orak, M.; Tasdemir, N.OBJECTIVES: Peripheral neuropathy is a well-documented disabling sequela of major burn injury. These lesions are associated with both thermal and electrical injuries that may be frequently undiagnosed or overlooked in clinical settings. The purpose of this study was to evaluate the prevalence of burn-related neuropathy in our database and to investigate the clinical correlates for both mononeuropathy and generalized peripheral polyneuropathy. PATIENTS AND METHODS: Out of 648 burn patients, admitted to our clinic forty-seven burn patients with the diagnosis of peripheral neuropathy were evaluated retrospectively. The demographic and clinical data collected were gender, age, degree, site and percent surface area of burn, type of burn, and the results of electrodiagnostic examination, including electromyography and nerve conduction assessments and associated pathology if existed. RESULTS: Peripheral neuropathy is the most frequent disabling neuromuscular complication of burn, that may be undiagnosed or overlooked. In current study, peripheral neuropathy associated with burn all of our patients were identified by electrodiagnostic study. After treatment in Burn Unit, clinical and electrodiagnostic studies were applied. Motor and sensory distal latencies were prolonged and sensory nerve action potentials reduced in amplitude. CONCLUSIONS: The findings of our study have shown that polyneuropathies and axonal neuropathy were more frequent than mononeuropathy and demyelination.Öğe Post-stroke sexual functioning in first stroke patients(Wiley, 2008) Tamam, Y.; Tamam, L.; Akil, E.; Yasan, A.; Tamam, B.Background and purpose: Although physical problems after stroke have been well studied, there is little information on one of the crucial aspects of the quality of life of those patients, namely sexual functioning and satisfaction. The aim of this study was to assess the impact of stroke on sexual functioning in a stable cohort of Turkish stroke patients with mild or no disability and to assess the relationship between post-stroke sexuality and a number of socio-demographic, clinical and laboratory variables. Methods: The sexual functioning of 103 Turkish stroke patients with no disability or mild disability was assessed in two consecutive interviews along with clinical and sociodemographic features. NIH stroke, Glasgow coma, Barthel, and Rankin scales were also applied to assess neurologic status and disability. Results: Most of the patients were male (61%) and illiterate (70%). There was a significant difference between the baseline and post-stroke frequency of sexual activity of the patients. The differences between baseline and post-stroke vaginal lubrication, orgasms and satisfaction were all statistically significant. This latter difference was significant for both genders. Frequency of coitus both prior to and after the stroke was significantly different between males and females. Erection and ejaculation of the males was significantly affected by the stroke, and lubrication and orgasm was affected in the females. Interestingly, fear of recurrent stroke did not differ between genders. Discussion and Conclusion: Our study has shown that Turkish stroke survivors have sexual health needs during the rehabilitation process, though this has not been addressed previously. Sexual health needs seem to be affected by cultural factors and biases.Öğe Prevalence of dementia one year after stroke(Elsevier Science Bv, 2015) Tamam, B.; Tamam, Y.[Abstract Not Available]Öğe Significance of inflammation markers in stroke(Wiley, 2015) Tamam, Y.; Akil, E.; Tamam, B.[Abstract Not Available]
