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Öğe A case of zosteriform lichen planus developing after extracorporeal shockwave lithotripsy(2012) Turan E.; Akay A.; Yesilova Y.; Türkçü G.Lichen planus is a relatively common papulosquamous skin disease of unknown etiology. It is characterized by flat-topped, shiny pinkish-purple papules and plaques on the skin or mucous membranes. The zosteriform type is a rare variant of lichen planus with dermatomal or zonal distribution. A 29-year-old female patient was admitted to our clinic with a 2-month history of a pruritic eruption on the dermatomes on the left between T6-T10. Based on clinical and histological findings, the patient was diagnosed with zosteriform lichen planus. The patient had undergone extracorporeal shock wave lithotripsy (ESWL) for left kidney stones two weeks before the appearance of the lesions. There was no history of skin diseases with dermatomal distribution including herpes zoster in the lesion area. This condition was considered as an isomorphic response following ESWL. © 2012 Dermatology Online Journal.Öğe Clinical and histopathological features of patients with cicatricial marginal alopecia(Turkiye Klinikleri, 2014) Akkurt Z.M.; Uçmak D.; Do?ruk Kaçar S.; Alabalik U.; Karabulut P.; Türkçü G.; Arica M.Objective: The aim of this study was to investigate the clinical and histopathologic characteristics of patients presenting with band-shaped alopecia of the temporal and frontal areas who had no history of traction. Material and Methods: Patients with cicatricial marginal retrospective study were included in this retrospective study. Severity of disease was classified as mild, moderate and severe according to the density of hair and size of lesions. Classification of the alopecia was made as follows: "bitemporal" in patients with involvement of only the temporal areas, "band-like" in patients with involvement of both temporal areas and the frontal area, and "other" in patients which did not fit the previous classifications. Dermoscopic findings were noted. Previous biopsy samples were restained with Masson Trichrome, CD3, CD1a, CD20 and CD68 and re-evaluated. Results: A total of 20 patients were included in the study. The mean age of the patients was 27,68 (15-41) years and the mean disease duration was 2,33 years. The most frequently reported symptoms were moderate-to-severe pruritus and mild pain. The disease was mild in nine, moderate in seven and severe in four patients (45,0%, 35,0% and 20,0%, respectively). The frontal and temporal hairline was intact and had in all patients. Eight patients had a bitemporal, eight had a band-like pattern of disease, whereas the rest were of other patterns. No signs of inflammation, including erythema, pustules, were observed on the lesions. On dermoscopy, decreased hair density, decreased number of follicles and hair shafts with reduced diameters were seen in all patients. Histopathologic findings of the 14 patients who had consented to biopsy were all similar. Decrease in number of hair follicles, perifollicular fibrosis and retention of sebaceous glands were notable findings. Inflammatory cells were very scarce. Conclusion: Cicatricial marginal alopecia is a type of alopecia seen in females which can seriously affect the cosmetic well-being of patients. An intact hairline and lack of inflammation are characteristic properties of the disease. Copyright © 2014 by Türkiye KlinikleriÖğe Generalized pustular psoriasis in two children: Acitretin therapy: Case report(Turkiye Klinikleri, 2014) Uçmak D.; Akkurt Z.M.; Türkçü G.; Acar G.; Akdeniz S.; Arica M.Von Zumbusch type pustular psoriasis is rarely seen in pediatric patients. Attacks of pustular psoriasis are characterized by fever that lasts several days, followed by sudden onset of pustules. The pustules are disseminated over the trunk and extremities, including the nail beds palms, and soles. Acitretin, alone, or combined with oral corticosteroids, is the first-line treatment method. Methotrexate or cyclosporine may also be used. Acitretin is a second generation aromatic retinoid. It takes effect by regulating keratinocyte proliferation and differentiation. A two-yearold girl and a three-year-old boy, presented with widespread pustules on an erythematous background, accompanied by fever and leukocytosis. Skin and blood cultures were negative. A diagnosis of Von Zumbusch type pustular psoriasis was made. We present two pediatric cases of generalized pustular psoriasis responding to acitretin rapidly and effectively. Copyright © 2014 by Türkiye Klinikleri.Öğe Herpes simplex superinfection with hailey-hailey disease: Case report(Turkiye Klinikleri, 2013) Uçmak D.; Harman M.; Akkurt Z.M.; Türkçü G.; Acar G.Hailey-Hailey disease (familial benign pemphigus) is an autosomal dominant acant-holytic dermatosis. The disease shows painful erosions and vesicles situated on an erythematous background especially in the intertriginous area. Herpes simplex infection associated with Hai-ley-Hailey disease differs from eczema herpeticum in that it is more localized. A 55-year-old female presented with vesicular lesions on the edge of wide inguinal erosions. A Tzanck smear revealed single hypertrophic nucleated acantholytic round cells with basophilic cytoplasm and one or two marked nucleoli at the periphery of the nucleus, adjacent to the nuclear membrane. Herpes simplex superinfection of Hailey Hailey disease is very rare and may not come to mind in diagnosis. A Tzanck smear, which is faster and easier than other tests for diagnosis, should be undertaken when there is clinical suspicion of herpes infection and antiviral treatment should be administered without delay. Copyright © 2013 by Türkiye Klinikleri.
