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Öğe Association Between Neutrophil to Lymphocyte Ratio and Severity of Coronary Artery Disease(Sage Publications Inc, 2014) Kaya, Hasan; Ertas, Faruk; Soydinc, Mehmet Serdar[Abstract Not Available]Öğe Atrial Fibrillation in Turkey: Epidemiologic Registry (AFTER) study design(Turkish Soc Cardiology, 2013) Ertas, Faruk; Kaya, Hasan; Yuksel, Murat; Soydinc, Mehmet Serdar; Alan, Sait; Ulgen, Mehmet SiddikObjective: Atrial fibrillation (AF) is an important health problem in Turkey. However, no prospective, multicenter, large trial reflecting national data has been published so far. Therefore, the aim of this study was to follow, analyze and evaluate patients with AF in a large multicenter nation-wide trial. Methods: Two thousand three hundred consecutive patients with AF in their electrocardiogram, reflecting all the population of seven geographical regions of Turkey will be included in the study. The patients will be followed up for two years and death, transient ischemic attack, stroke, systemic thromboembolism, major bleeding, hospitalization will be recorded as the primary end-point. Results: Will be available at the end of the study; preliminary results will be due December 2012. Conclusion: General risk profile of patients with AF, frequency of anticoagulation, frequency of effective treatment and risks of bleeding will be evaluated according to the current guidelines. Major adverse events and their independent predictors will be determined.Öğe Diurnal Blood Pressure Pattern in Patients with Ischemic and Dilated Cardiomyopathy(Elsevier Science Inc, 2013) Tastan, Ercan; Ugurlu, Hasan Murat; Mercen, Mehmet Han; Kaya, Ilyas; Bilik, Mehmet Zihni; Soydinc, Mehmet Serdar[Abstract Not Available]Öğe Low serum free triiodothyronine levels are associated with the presence and severity of coronary artery disease in the euthyroid patients: an observational study(Aves Yayincilik, 2012) Ertas, Faruk; Kaya, Hasan; Soydinc, Mehmet SerdarObjective: The aim of this study is to investigate the relationship between serum thyroid hormone levels that are within the normal range and the presence and severity of coronary artery disease (CAD) in patients referred for coronary angiography. Methods: In this observational study, we enrolled 119 consecutive patients (77 men, mean age 60.7 +/- 13.8 years) who underwent coronary angiography. Blood samples were tested for thyroid stimulating hormone (TSH), free triiodothyronine (FT3) and free thyroxine (FT4) concentrations. Additionally, risk factors, clinical characteristics and angiographic results were obtained. The patients were separated into two groups according to the Gensini score as those with mild or severe atherosclerosis. Statistical analysis was performed using the Chi-square, Mann-Whitney U, correlation and logistic regression tests, and ROC analysis. Results: FT3 levels were significantly lower in subjects with CAD (4.0 +/- 0.7 vs. 4.6 +/- 0.6 pmol/L; p<0.001). Moreover, lower FT3 levels were found in patients with severe atherosclerosis (3.9 +/- 0.7 vs. 4.5 +/- 0.6 pmol/L; p<0.001). Logistic regression analysis demonstrated that the lower FT3 levels were associated with the presence (OR =0.266, 95% CI: 0.097-0.731, p=0.01) and severity (OR=0.238, 95% CI: 0.083-0.685, p=0.008) of CAD. In the ROC analysis, a level of FT3 <= 4.2 pmol/L was found to predict the presence of CAD with 69% sensitivity and 71% specificity (AUC: 0.744, 95% CI: 0.653-0.834, p<0.001); and the severity of CAD with 75% sensitivity and 67% specificity (AUC: 0.733, 95% CI: 0.642-0.824, p<0.001). Conclusions: FT3 levels within the normal range were inversely correlated with the presence and severity of CAD. Moreover, lower FT3 concentrations were correlated with the Gensini score and independently predicted the presence and severity of CAD. Thus, the FT3 levels may be used as the indicator of increased risk for CAD. (Anadolu Kardiyol Derg 2012; 12: 591-6)Öğe Percutaneous Closure of Patent Ductus Arteriosus: Experience of a Tertiary Referral Center(Elsevier Science Inc, 2013) Kaya, Hasan; Ertas, Faruk; Polat, Nihat; Yildiz, Abdulkadir; Akil, Mehmet Ata; Soydinc, Mehmet Serdar; Alan, Sait[Abstract Not Available]
