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Öğe Diabetik anne çocuklarında kalp yapısı ve fonksiyonlarının ekokardiyografik değerlendirilmesi(2018) Soran, MustafaDicle Üniversitesi Tıp Fakültesi Çocuk Sağlığı ve Hastalıkları Anabilim Dalı Yenidoğan Servisine Mart 94 ve Eylül 96 tarihleri arasında yatırılan ve annesinde diabet tespit edilen 26 yenidoğanın 7'si (%26.9) kız, 19'u (%73.1) erkek idi. Yenidoğanların 17'si (%65.4) LGA, 10'u (%34.5) AGA'lı idi. Annelerin White sınıflamasına göre, 9'u (%34.6) gestasyonel, 7'si (%26.9) A grubu, 8'i (%30.8) B grubu ve 2'si (%7.7) G grubu diabetli ve 9'u insülin kullanıyordu. Çalışmamızda elde ettiğimiz ortalama ekokardiyografi değerleri; Sistolik fonksiyonların göstergesi olan ejeksiyon fraksiyonu ve fraksiyonel kısalma yüzdesi (p>0.05), diabetik anne çocuklarında değişmemiş olarak bulundu. Diastolik fonksiyonların göstergesi olan E peak ve A peak değişmemiş (p>0.05), E/A oranı düşük tespit edildi (p<0.05). Sol ventrikül end-diastolik volümü (p>0.05) ve strok volüm (p>0.05) değişmemiş olarak bulundu. Sonuç olarak, diabetik anne çocuklarında diabetin süresi, şiddeti ve kontrolüyle ilişkili olarak artan asimetrik septal hipertrofi ve sol ventrikül kas kitlesi tespit edilir. Kalbin sistolik ve diastolik fonksiyonları, kalp yetersizliği ve hipertrofik subaortik stenoz yoksa etkilenmemektedir.Öğe The effect of alternate-day low dose prednisolone on bone age in children with steroid dependent nephrotic syndrome(Kluwer Academic Publishers, 1997) Bircan, Zelâl; Soran, Mustafa; Yıldırım, İdris; Doğan, Sait Murat; Şahin, A.; Bilici, Aslan; Danacı, M.; 0000-0001-8840-4365Radius, ulna, short bones (RUS), carpal (CARP) bone age (BA), tibial corticodiaphyseal (C/D) ratio and trabecular aspect were assessed in 19 children with steroid dependent nephrotic syndrome and 15 age matched healthy children. Both RUS and CARP BA were significantly lower than in the controls. Trabecular aspect and tibial C/D ratio did not show any statistical significance. There was a positive correlation between HSDS and RUS BA delay (r =0.476, p<0.05); CARP BA delay and RUS BA delay (r=0.563, p<0.01) and RUSBA and CARP BA (r=0.891, p<0.001). In conclusion, RUS and CARP BA are both retarded and positively correlated in steroid dependent nephrotic children.Öğe The effect of metabolic acidosis on serum apolipoprotein A I and apolipoprotein B levels in children with chronic renal failure(1997) Bircan, Zelâl; Kaplan, Abdurrahman; Soran, Mustafa; Söker, Murat; Kervancıoǧlu, Mehmet; Şahin, A.; Kılınç, MetinIn this report serum apolipoprotein A I (Apo A I) and apolipoprotein B (Apo B) levels were determined in children with chronic renal disease (CRD) during metabolic acidosis, after the correction of metabolic acidosis and in healthy children to look for the effect of metabolic acidosis on Apo A I and B levels. It was found that Apo A I levels were significantly decreased during metabolic acidosis (p < 0.05) but Apo A I/Apo B ratios were not affected before and after the correction of acidosis in the CRD group (p > 0.05) although it was significanlty different from those in the controls (p < 0.01).Öğe Factors Affecting the Number of Shock Wave Lithotripsy Session in Children with Renal Stones: Are age and Radiolucency the Predictors of Success?(Aves, 2017) Kocaoglu, Canan; Soran, Mustafa; Kocaoglu, Celebi; Onen, AbdurrahmanObjective: We aimed to investigate the effectiveness of shock wave Lithotripsy (SWL) and factors affecting seance number while treating children with renal stones. Materials and Methods: A total of 50 children (53 renal units) who underwent SWL for renal stones between 2012 and 2014 were investigated retrospectively. The demographics of patients, the number, size, side, location, and radiolucency of stones in kidneys, placement of JJ stents, shock number, energy, seance number, stone- free rate, and complications were noted. Results: Patients involved 25 girls and 25 boys with a median age of 4.0 years ranging from eight months to 16 years (21 <= 3y). Stones were located in the renal pelvis and calyxes in 20 and 33 patients, respectively. Of the renal stones, 33 were single and 20 were multiple. The mean stone size was 11.02 +/- 5.4 mm. Success rates were 45.3, 75.5, and 92.5% after seances 1, 2, and 3, respectively. Per seance, the mean SWL shock waves and energy were 1219 +/- 262 and 12.6 +/- 0.9 kV. A significant relationship was found between the need for a third seance and patient age (<= 3 years and > 3), radiolucent and radiopague, <= 10 mm and > 10 mm or single and multiple stone (p< 0.05). However, no significant relationship was found between success rate and age; sex; number, size, location, and side of stones; and radiolucent stones. Conclusions: Age, radiolucency, stone size, and number of stones were significant predictors of SWL success in children. We observed that stone- free status is achieved more quickly, even within the first or second SWL seances by significantly decreasing the need for the third seance in group age <= 3 years, radiolucent, <= 10 mm or single renal stones.Öğe Kronik böbrek yetmezlikli çocuklarda metabolik asidozun büyüme hormonu uyarı testlerine etkisi(Çocuk Nefroloji Derneği ve Hacettepe Üniversitesi Tıp Fakültesi, 1996) Yıldırım, İdris; Bircan, Zelal; Soran, Mustafa; Kervancıoğlu, Mehmet; Haspolat, Yusuf KenanGelişme geriliği kronik böbrek yetmezliğinin (KBY) önemli sorunlarındandır. Metabolik asidoz KBY'de gelişme geriliği yapan nedenlerden biridir. Metabolik asidozun, KBY'de büyüme hormonu salınımı üzerine etkilerini saptamaya yönelik sınırlı sayıda çalışma vardır. Metabolik asidozu saptanan dokuz KBY'li ve sekiz normal prepubertal çocuk üzerinde çalışıldı.
