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Öğe Hemophilia Requiring Surgical Attention: A Report of two Cases(Wiley-Blackwell, 2017) Soker, M.; Uzel, H. V.; Soker, S.; Aktar, F.[Abstract Not Available]Öğe THE IMMUNOHISTOCHEMICAL AND ULTRASTRUCTURAL EVALUATION OF PERICYTES IN HUMAN FULL TERM PLACENTAS OF GESTASYONAL DIABETES MELLITUS(Carbone Editore, 2013) Deveci, E.; Soker, S.; Turgut, A.; Aktas, A.; Ayaz, E.; Sak, S.; Seker, U.Pericytes, vessel wall plays a stabilizing role in the regulation of blood flow in the microcirculation. The purpose of this study is based on non-diabetic pregnancies complicated by gestational diabetes pregnancies to investigate the morphological structure of pericyte cells. In this study, as a control group human placental tissues from normotensive pregnancies was collected from diabetic wome at 28-35 weeks of gestation. Pericytes with smooth alpha-actin positive cells, endothelial cells, and painted like a belt was surrounded. Pericytes, capillary plexus and endothelial cells of large vessels in the mesenchyme around the middle shows desmin positive reaction. Placental micro vessels examined by transmission electron microscopy showed many pericytes. Placentas of gestational diabetes group, heterochromatin nucleus hypertrophy, dilatation of endoplasmic reticulum, mitochondria cristae in length, shortening was observed thickening of the filamentary structure. The contractile function of the barrier formed by endothelial cells, pericytes and can increase the contractions were consideredÖğe INTRACRANIAL HAEMORRHAGE IN FACTOR XIII DEFICIENCY: REPORT OF THREE CASES(Wiley, 2020) Soker, M.; Uzel, H.; Oncel, K.; Soker, S.; Celik, M.[Abstract Not Available]Öğe Perioperative management and outcome of urgent appendectomy in a patient with severe hemophilia(Wiley-Blackwell, 2015) Soker, M.; Zeytun, H.; Soker, S.; Sahin, C.[Abstract Not Available]Öğe Successful Management of Intracranial Bleeding in a Patient With Factor X Deficiency by a Prothrombin Complex Concentrates(Wiley-Blackwell, 2016) Soker, M.; Uzel, H. V.; Soker, S.; Ceviz, A.; Yilmaz, A.[Abstract Not Available]Öğe Successful management of ovarian cyst rupture in a patient with factor V deficiency: a case presentation(Wiley, 2018) Soker, M.; Uzel, V. H.; Oncel, K.; Soker, S.[Abstract Not Available]Öğe Successful use of recombinant activated factor VII (rFVIIa) perioperative management and outcome of urgent appendectomy in a patient with congenital factor VII deficiency(Wiley, 2019) Soker, M.; Uzel, H.; Oncel, K.; Basuguy, E.; Soker, S.[Abstract Not Available]Öğe Ultrastructural Changes in the Kidney Cortex of Rats Treated with Lead Acetate(Soc Chilena Anatomia, 2011) Deveci, E.; Soker, S.; Baran, O.; Tunik, S.; Ayaz, E.; Deveci, S.The purpose of this study was to investigate the ultrastructural effects of lead on the kidney cortex of rats. Wistar Albino rats (180-200g body weight) were divided into a controlled and lead acetate-exposed group. Rats received lead acetate at 500 ppm in their drinking water for 60 days. Both groups were fed with the same standard food, but lead acetate was added to the drinking water. During the experimental period, blood samples were taken from the abdominal aorta of the anesthetised animals. At the end of exposure, body weight and blood lead levels were measured. The kidney tissue samples were prepared and analyzed by light and transmission electron microscopy. Cortical renal tubules show various degenerative changes with focal tubular necrosis invaded by inflammatory cells. The ultrastructural alterations found in lead acetate-treated rats were a diminution in the amount of filtration slits, increased fusion of foot processes in epithelial cells of the glomeruli, increase of lysosomal structures and pinocytic vesicles as well as large mitochondria in proximal tubule cells.
