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    Öğe
    Comparison of sexual abuse survivors from two different geographical regions of Turkey in terms of the sociodemographic and abuse-related characteristics
    (Yerkure Tanitim ve Yayincilik, 2014) Simsek S.; Uysal C.; Bez Y.; Gencoglan S.
    Objective: The aim of this study is to compare the sociodemographic and abuse-related data of the children who have presented to the Antalya and Diyarbakir University hospitals due to sexual abuse. Method: The patient files of 172 children between the ages of 4-17 presented to the Akdeniz University, Department of Child and Adolescent Psychiatric Health and Diseases (CAPHD) Clinic within the year 2010, and of 167 children between the ages of 4-17 presented to the Dicle University CAPHD Clinic during the year 2012 were scanned and the sociodemographic and abuse-related data of the patients were recorded. Results: In the Diyarbakir group, the total years of education of the child, the total years of education of the mother, and the total years of education of the father were significantly lower, while the mean number of the siblings was significantly higher. The number of the male abuse survivors in the Diyarbakir group was significantly higher. The family structure where the parents are alive and living together was significantly more frequent in the Diyarbakir group. No difference in terms of the occurrence of penetration and relationship with the abuser was observed between the groups. Conclusion: Within the framework of this study, the characteristics of the survivors of abuse between two socioculturally, economically and ethnically different regions of Turkey (the Mediterranean region and the south-east Anatolian region) have been investigated. This study has demonstrated that some of the sociodemographic and abuse-related characteristics of sexual abuse in Turkey differs between these regions. We are of the opinion that efforts to prevent sexual abuse should be restructured in the light of these results. For instance, prevention of child labour, increasing the literacy rate of the individuals and promoting family planning efforts in south-east Anatolia should be the primary focus of these efforts.
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    Öğe
    Ethyl pyruvate prevents ischemia reperfusion injury in isolated perfused rat heart
    (2013) Akkoc H.; Tunik S.; Kelle I.; Gurkan A.; Erdogmus Z.; Simsek S.; Erdinc M.
    The aim of the present study was to investigate the protective effect of ethyl pyruvate (EP) against ischemia reperfusion (I/R) injury in isolated rat heart. Male Sprague-Dawley rats were divided into three groups (n = 8); Group 1: Control group, Group 2: I/R, Group 3: I/R+EP. Ischemia was produced for 30 min by blocking the perfusion with Krebs Henseleit solution and it was followed by reperfusion for 60 min. In group 3, EP (2 mmol/L) was added into Krebs Henseleit solution after stabilization period. EP did not change the number of ?-smooth muscle actin positive vessels and expression of Bcl-2 and desmin. Treatment with EP significantly reduced I/R induced extension in infarct size (p < 0.001) and release of lactate dehidrogenase (p < 0.001) and creatine phosphokinase (p < 0.05). Myocardial I/R injury significantly increased oxidative stress index and malondialdehyde, total oxidant status levels and significantly decreased paraoxonase actvity and total antioxidant status (p < 0.05). On the other hand, alterations in these biochemical indices due to I/R injury were attenuated by EP treatment (p < 0.01). These results show that ethyl pyruvate prevents ischemia reperfusion injury in isolated perfused rat heart.
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    Öğe
    A middle aged woman with mosaic turner syndrome: A case report
    (2011) Simsek S.; Yalinkaya A.; Oral D.; Turkyilmaz A.; Tekes S.; Budak T.
    Turner syndrome is a disorder of females is characterized by the absence of all or part of a normal second sex chromosome. Turner syndrome occurs in 1 in 4000 live-born girls and approximately 5 to 10 percent of them have mosaic isochromosome 45,X/46,X,i(Xq). Turner syndrome is associated with reduced adult height and with gonadal dysgenesis, leading to insufficient circulating levels of female sex steroids and to infertility. Osteoporosis and high risk of fractures are features in adults with Turner syndrome. In this study, we present a delayed case of Turner syndrome with primary amenorrhea, short stature, osteoporosis and high risk of fractures. This case has ignored due to social and economic conditions, therefore we think that the patient can be considered for publication.