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    Clinical, Haematological and Biochemical Findings in Sheep Naturally Infected with Dermatophilus congolensis
    (Natl Information Documentation Centre, 2022) Simsek, Aynur; Kochan, Akin; Alp, Simten Yesilmen
    Dermatophilus congolensis infection in sheep is manifested as matted tufting, entanglement, hardening and loss of wool, and thickening and itching of the skin, altogether which eventually results in economic losses. We investigated the clinical, hematological and biochemical findings in sheep naturally infected with Dermatophilus congolensis. For this purpose, 35 infected Akkaraman sheep (aged: 3-4 years, belonging to a flock of 200 animals) were referred to Prof Dr. Servet SEKIN Polyclinic of the Dicle University, Veterinary Faculty with various skin problems were included. The infected sheep presented with crusted skin lesions, matted wool tufts, alopecia, and pruritus. Their biochemical serum analyses revealed increased serum alkaline phosphatase, alanine aminotransferase, lactate dehydrogenase, blood urea nitrogen, total protein, albumin and calcium levels, and decreased creatinine, sodium and potassium levels in comparison with the control animals. The infected animals were treated with parenteral amoxicillin/clavulanic acid (Synulox (R)-Zoetis; 8.75 mg/kg body weight, i.m., once daily for 5 days) and local povidone-iodine (Batimer (R)-Esmira) administration, and observed for response to the treatment regimen. We found that Dermatophilus congolensis infection causes skin and wool damage in sheep, along with alteration in the serum biochemical parameters.
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    Detection of Theileria annulata and T. buffeli in Cattle by Multiplex PCR in Diyarbakir Area
    (Kafkas Univ, Veteriner Fakultesi Dergisi, 2012) Deniz, Ahmet; Oncel, Taraneh; Icen, Hasan; Simsek, Aynur
    The aim of this study was to detect Theileria annulata and T. buffeli in healthy cattle by multiplex PCR method in Diyarbakir area of Turkey. For this purpose a total of 100 blood samples were collected within the tubes coated with EDTA from cattle in Diyarbakir area. At the same time, peripheral blood smears were also prepared from each animal for microscopic examination. Additionally, the cattle were also examined for tick infestation. Tick infestation was not observed on the examined cattle. In microscopic examination of the blood smears, 5 of the 100 cattle were detected as positive for Theileria spp. In molecular analyses of the blood samples, T. annulata was detected in 23 cattle by multiplex PCR. In one cattle, T. annulata + T. buffeli was also determined via multiplex PCR. Results indicated that, T. annulata is commonly observed in cattle in Diyarbakir.
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    Diaphragmatic hernia in a sheep - a case report
    (Univ Zagreb Vet Faculty, 2018) Simsek, Aynur; Yaman, Turan; Icen, Hasan; Kochan, Akin
    A two-year-old sheep was referred to the clinics of the Department of Internal Medicine of Dicle University, Faculty of Veterinary Medicine, with signs of anorexia, abdominal tympany and constipation. The clinical examination of the animal revealed the presence of respiratory failure associated with weaker lung sounds on the right side of the body when compared to the left side. There were no ruminal movements, and when the rumen was probed with a stomach tube, no ruminal content was obtained. The animal was euthanized upon the request of the owner, and a necropsy was performed. At necropsy, it was observed that the left hepatic lobe had protruded into the thoracic cavity through a defect in the diaphragm, and that a diaphragmatic hernia had developed.
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    Serum mineral levels and haematobiochemical parameters in buffalo calves with allotriophagy (pica syndrome)
    (Polish Soc Veterinary Sciences Editorial Office, 2023) Kochan, Akin; Simsek, Aynur; Arica, Enes
    Pica is defined as a depraved or abnormal appetite characterized by licking and eating non-nutritive substances. The aim of this study was to report changes in the serum mineral levels and haematobiochemical parameters of buffalo calves with pica. The study included 30 buffalo calves exhibiting pica behaviour, such as licking stall walls or eating wool and non-food items (pica group), and 6 buffalo calves without the signs of pica behaviour (control group). The age of both groups ranged between 1 and 6 months. In the pica group, the haematological analysis revealed a decrease in red blood cells (P < 0.001) and red cell distribution width (P < 0.05) as well as an increase in the mean corpuscular volume and mean corpuscular haemoglobin (P < 0.001), whereas the biochemical parameters were characterized by an increase in aspartate aminotransferase (P < 0.01), alanine aminotransferase (P < 0.001) and lactate dehydrogenase (P < 0.05) levels and a decrease in creatinine and glucose (P < 0.01) levels. Furthermore, the pica group showed a significant decrease in serum manganese, iron, zinc, selenium (P < 0.001) and copper (P < 0.01) concentrations. In conclusion, it was determined that deficiencies in the levels of serum iron, copper, zinc, manganese and selenium play an important role in the aetiology of pica in buffalo calves.
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    Viral and Bacterial Pathogen Isolated and Identified from Pneumonic Calves in Region of Diyarbakir and its Treatment with Tulathromycin
    (Medwell Online, 2009) Icen, Hasan; Sekin, Servet; Simsek, Aynur; Yesilmen, Simten; Isik, Nurettin
    We tested the field efficacy of a new antibiotic tulathromycin in the treatment of naturally occuring bovine respiratory disease beef calves with rectal temperatures greater than 39.5 degrees C and signs compatible bovine respiratory disease were entered into the trial. This study was performed on 30 mixed breed beef calves with bronchopneumonia, 8-10 months old. Bacteriological and serological examinations were performed in nasal swabs and blood samples collected from beef calves. Klebsiella pneumoniae, Mannheimia haemolytica, Coagulase (+) Staphylococcus sp., Streptococcus sp. were isolated from bacteriological examinations of bronchoalveolar lavage. Serum samples were tested serologically for antibodies to infectious bovine rhinotracheitis, Parainfluenza-3, Bovine adenovirus and Bovine viral diarrhea viruses. All samples were positive for antibodies to infectious bovine rhinotracheitis, Parainfluenza-3, Bovine adenovirus and Bovine viral diarrhea viruses. Calves were assigned to receive tulathromycin (2.5 mg kg(-1) bodyweight, subcutaneously). Clinical measures of efficacy included mortality, rectal temperatures, pulsation, respiratory rate, assesment of treatment succes or failure and number of relapses. Four calves relapses and needed second enjection. No significant adverse reactions were noticed with tulathromycin. After the treatment, all the calves were cured. Results indicate that Tulathromycin administration was found to be effective in the treatment of bovine respiratoy diseases (especially, in bacterial infections) of beef calves in region of Diyarbakir.
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    Viral and Bacterial Pathogen Isolated and Identified from Pneumonic Calves in Region of Diyarbakir and its Treatment with Tulathromycin
    (Medwell Online, 2009) Icen, Hasan; Sekin, Servet; Yesilmen, Simten; Isik, Nurettin; Simsek, Aynur
    We tested the field efficacy of a new antibiotic tulathromycin in the treatment of naturally occuring bovine respiratory disease beef calves with rectal temperatures >39.5 degrees C and signs compatible bovine respiratory disease were entered into the trial. This study was performed on 30 mixed-breed beef calves with bronchopneumonia, 8-10 months old. Bacteriological and serological examinations were performed in nasal swabs and blood samples collected from beef calves. Klebsiella pneumoniae, Mannheimia haemolytica, Coagulase (+) Staphylococcus and Streptococcus sp. were isolated from bacteriological examinations of bronchoalveolar lavage. Serum samples were tested serologically for antibodies to Infectious bovine rhinotracheitis, Parainfluenza-3, Bovine adenovirus and Bovine viral diarrhea viruses. All samples were positive for antibodies to Infectious bovine rhinotracheitis, Parainfluenza-3, Bovine adenovirus and Bovine viral diarrhea viruses. Calves were assigned to receive tulathromycin (2.5 mg kg(-1) bodyweight, subcutaneously). Clinical measures of efficacy included mortality, rectal temperatures, pulsation, respiratory rate, assesment of treatment succes or failure and number of relapses. Four calves relapses and needed second enjection. No significant adverse reactions were noticed with tulathromycin. After the treatment, all the calves were cured. Results indicate that tulathromycin administration was found to be effective in the treatment of bovine respiratoy diseases (especially in bacterial infections) of beef calves in region of Diyarbakir.