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Öğe Could platelet indices be a predictive marker for pulmonary embolism in patients with deep venous thrombosis(Cardiology Academic Press, 2014) Sevuk U.; Bahadir M.V.; Altindag R.; Ay N.; Ay D.; Demirtas E.; Ayaz F.There is a need to develop simple and reliable noninvasive tests that can accurately identify patients with pulmonary embolism (PE) even in small hospitals or clinics. Aim of this study was to investigate the value of mean platelet volume (MPV) and platelet distribution width (PDW) for predicting occurrence of PE in patients with deep venous thrombosis (DVT). Group 1 consisted of 50 patients with acute DVT and group 2 consisted of 50 patients with acute DVT who developed PE during follow-up. MPV and PDW levels at the time of PE diagnosis were higher in group 2 than group 1(p<0.001 and p=0.026, respectively). ROC analysis revealed that a 5.2% increase in admission PDW during follow-up provided 70% sensitivity and 82% specificity (AUC, 0.80) and a 6.6% increase in admission MPV during follow-up provided 74% sensitivity and 83% specificity ( AUC, 0.84) for prediction of PE occurrence in patients with DVT. PDW and MPV levels at the time of PE diagnosis were independent risk factors for the occurrence of PE in patients with DVT. MPV and PDW can be used to predict occurrence of PE in DVT patients.Öğe Normal thyroid function and its relationship with carotid artery stenosis in patients with coronary artery disease(Cardiology Academic Press, 2014) Sevuk U.; Erdolu B.; Kubat E.; Altindag R.; Baysal E.; Yaylak B.; Bahadir M.V.This study was carried out to determine the relationship between normal ranges of thyroid function and internal carotid artery stenosis (ICS) in patients with coronary artery disease (CAD). 100 euthyroid patients with concomitant ICS and CAD (group 1) were analyzed retrospectively. Comparison was made with 100 euthyroid patients with CAD who were free of any carotid artery lesions (group 2). Normal ranges of FT4 were classified into 3 groups: low-normal, mid-normal, and high-normal thyroid groups. Mean FT4 level in group 1 was significantly higher than group 2 (p=0.02). Percentage of patients in high-normal FT4 group was significantly higher in group 1 than in group 2 (p< 0.001). According to the categories of FT4, the percentage of patients with ICS in the high- normal FT4 group (76.1%) was significantly higher than low-normal (39.4%) and mid-normal group (43%) (p=0.003 and p<0.001 respectively). Logistic regression analysis showed that high-normal FT4 group was independently associated with ICS (OR 4, 95% CI 1.84-8.77, p<0.001). Increased FT4 levels, even within the reference range was associated with a higher percentage of ICS in euthyroid patients with CAD, independent of classical risk factors for atherosclerosis.Öğe RE: Hemogram parameters for predicting pulmonary embolism in patients with deep venous thrombosis(Dove Medical Press Ltd., 2015) Sevuk U.; Bahadir M.V.; Altindag R.; Baysal E.; Yaylak B.; Ay N.; Ayaz F.[No abstract available]
