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Öğe ARACHNOID GRANULATIONS: FREQUENCY AND DISTRIBUTION IN MULTI-DETECTOR ROW CT OF DURAL SINUSES(Taylor & Francis Ltd, 2009) Bayrak, A. H.; Akay, H. O.; Ozmen, C. A.; Senturk, S.Arachnoid granulations ore normal variants that protrude into the cerebral venous sinus lumen and produce focal defects in cerebral venography, contrast enhanced CT and MRI. It should be differentiated from other lesions within the dural sinus lumen that produce focal defects. In the present study, we investigated the frequency and positional distribution of arachnoid granulations with multi-defector row CT Simple post processing procedures on thin slice multi-detector row CT were performed. We found arachnoid granulations in nearly half of our participants. We observed that presence of arachnoid granulations showed no tendency in two sexes. No relationship between age and multiplicity, and an inverse relationship between age and the variants size existed. We concluded that as imaging technology continues to develop, the frequency with which normal variants are identified will also increase. Arachnoid granulations are a normal variant that all radiologists should be aware of and which should not be mistaken for pathological intra-sinus lesions. The relationship between characteristics of the variant (presence, number, size) and of the human subjects (gender, age) should be reviewed with larger samples.Öğe EXPRESSION OF E-CADHERIN, COX-2, P53 AND BCL-2 IN PROSTATE CARCINOMAS: CORRELATION WITH TUMOR DIFFERENTIATION AND METASTATIC POTENTIAL(Taylor & Francis Ltd, 2010) Ozekinci, S.; Uzunlar, A. K.; Senturk, S.; Gedik, Abdullah; Buyukbayram, H.; Mizrak, B.Prognostic factors of prostate cancer such as PSA stage Gleason grade and surgical margins have limitations they are inable to indicate metastatic potential The aim of this study was to investigate expression of e-cadherin cox-2 p53 and bcl-2 in prostate carcinomas and to search association with tumor differentiation and metastatic potential Eighty-seven prostate cancer specimens were retreived from tissue blocks embedded in parafin and expression patterns of e-cadherin cox-2 p53 and bcl-2 were investigated by immunoperoxidase method Gleason scoring system was used for tumor grading and expression patterns of these antibodies were compared among different tumor grades Seven cases (8%) had well-differentiated 39(45%) had moderately differentiated and 41 (47%) had poorly differentiated tumors Metastases were present in 31 patients (35%) There was a statistically significant association between tumor differentiation and expression of e-cadherin or bcl-2 (p < 0 01) however no association was found between tumor differentiation and expression of cox-2 or p53 (p > 0 01) There was no association between expressions of e-cadherin cox-2 p53 or bcl-2 and metastasis E-cadherin expression is less frequent in poorly differentiated tumors whereas bcl-2 expression is more frequent However there is no relation with metastatic potential and expression of these markers Expression of cox-2 and p53 is neither related to the degree of differentiation nor to the metastatic potentialÖğe Ultrasound as a diagnostic tool to differentiate acute from chronic renal failure(Dustri-Verlag Dr Karl Feistle, 2010) Ozmen, C. A.; Akin, D.; Bilek, S. U.; Bayrak, A. H.; Senturk, S.; Nazaroglu, H.Aim Renal ultrasound (US) is the most appropriate method for imaging renal failure; however, considerable overlap in renal size and renal echogenicity exists between normally and abnormally functioning kidneys We compared the sonographic features of kidneys in patients with renal failure to investigate the potential role of renal US to distinguish acute from chronic renal failure and assessed the diagnostic role of body surface area-corrected renal length compared to measured renal length Materials and methods We included 127 consecutive patients with serum creatinine levels higher than 3 mg/dl and 33 healthy volunteers The subjects with acute renal failure (ARF) and chronic renal failure (CRF) were compared for renal length, parenchymal thickness, parenchymal echogenicity, distinctness of the corticomedullary junction, and the presence of stones and cysts Results: No significant differences in age, serum albumin, creatinine, weight, height, or gender distribution were found between patients with ARF and those with CRF, except in serum hemoglobin. The flat and left kidney parenchymal thickness and renal length were significantly greater in ARF patients than in those with CRF (p < 0 0001). The mean parenchymal thickness and renal length were similar in ARF patients and the control group Grade I hyperechogenicity was the most common finding during sonography Conclusions Renal length, parenchymal thickness, and echogenicity differed significantly between patients with acute and chronic renal failure A renal US examination is still the most appropriate method for imaging renal failure and should be combined with other tests to distinguish acute from chronic renal failureÖğe Variations of the celiac trunk and hepatic arteries: a study with 64-detector computed tomographic angiography(Verduci Publisher, 2013) Gumus, H.; Bukte, Y.; Ozdemir, E.; Senturk, S.; Tekbas, G.; Onder, H.; Ekici, F.OBJECTIVES: The aim of the present study was to evaluate variations in celiac trunk and hepatic artery with multi-detector computed tomography (MDCT). PATIENTS AND METHODS: Totally 820 patients who underwent angiography of the abdominal aorta were evaluated. Anatomical findings were grouped according to the Michels classification. RESULTS: Several variations and/or anomalies were noted in 33.2% of the patients (n=272). The most common abnormality was Michels type III (10.1%), followed by type V (7.3%), type II (4.7%) and others. Type X was not observed in our series. We have noted additional, previously unclassified variations in 12 cases (1.5%). CONCLUSIONS: Preoperative knowledge of variant anatomy may assist in the selection of treatment options and surgical planning, which in turn facilitates surgical dissection and helps avoiding iatrogenic injury. MDCT angiography allows detailed visualization of the vascular anatomy.
