Yazar "Selvi, Yavuz" seçeneğine göre listele

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    Aripiprozole-induced diplopia: A case report
    (2013) Kaya, Mehmet Cemal; Aydın, Yıldız; Atlı, Abdullah; Selvi, Yavuz
    Diplopi çift görme olarak tanımlanan ve yaşam kalitesinibozan bir durumdur. Akut diplopi bazı genel tıbbiilaçlar ve psikotrop ilaç kullanımında görülmektedir.Aripiprazol D2 ve 5-HT1A reseptörlerine parsiyel agonistve 5-HT2A reseptörlerine antagonist aktivite gösterenatipik antipsikotik ajandır. Bu yazıda şizofreniformbozukluk tanısıyla takip edilen 24 yaşındaki birhastada, oral aripiprazol kullanımını takiben ortayaçıkan, diplopi olgusu bildirilmektedir. Klinisyenleraripiprazol tedavisiyle diplopi ortaya çıkabileceğiniakılda tutmalıdırlar.
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    Öğe
    Aripiprozole-Induced Diplopia: A Case Report
    (Kure Iletisim Grubu A S, 2013) Atli, Abdullah; Selvi, Yavuz; Yildiz, Aydin; Kaya, Mehmet Cemal
    Diplopia is a condition that involves seeing double and impairs quality of life. Acute diplopia can be seen with some general medical drugs and psychotropic drugs. Aripiprazole is a new atypical antipsychotic agent; it has partial agonist activity at D2 and 5-HT1A receptors and antagonist activity at 5-HT2A receptors. This paper reports development of diplopia, a rare adverse effect of psychotropic drugs, in a 24 year old patient with schizophreniform disorder following use of oral aripiprazole. Clinicians should keep in mind that diplopia may occur with aripiprazole treatment.
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    Mood and metabolic consequences of sleep deprivation as a potential endophenotype' in bipolar disorder
    (Elsevier, 2013) Aydin, Adem; Selvi, Yavuz; Besiroglu, Lutfullah; Boysan, Murat; Atli, Abdullah; Ozdemir, Osman; Kilic, Sultan
    It has been commonly recognized that circadian rhythm and sleep/wake cycle are causally involved in bipolar disorder. There has been a paucity of systematic research considering the relations between sleep and mood states in bipolar disorder. The current study examines the possible influences of sleep deprivation on mood states and endocrine functions among first-degree relatives of patients with bipolar disorder and healthy controls. Blood samples were taken at two time points in the consecutive mornings at predeprivation and postdeprivation periods. Participants simultaneously completed the Profiles of Mood States at two time points after giving blood samples. Plasma T3 and TSH levels increased after total sleep deprivation in both groups. Sleep deprivation induced TSH levels were reversely associated with depression-dejection among healthy controls. A paradoxical effect was defected for only the first-degree relatives of the patients that changes in plasma cortisol levels negatively linked to depression-dejection and anger-hostility scores after total sleep deprivation. Plasma DHEA levels became correlated with vigor-activity scores after sleep deprivation among first-degree relatives of bipolar patients. On the contrary, significant associations of depression-dejection, anger-hostility, and confusion-bewilderment with the baseline plasma DHEA levels became statistically trivial in the postdeprivation period. Findings suggested that first-degree relatives of patients with bipolar disorder had completely distinct characteristics with respect to sleep deprivation induced responses in terms of associations between endocrine Functions and mood states as compared to individuals whose relatives had no psychiatric problems. Considering the relationships between endocrine functions and mood states among relatives of the patients, it appears like sleep deprivation changes the receptor sensitivity which probably plays a pivotal role on mood outcomes among the first-degree relatives of patients with bipolar disorder. (C) 2013 Elsevier B.V. All rights reserved.