Yazar "Schachern, Patricia A." seçeneğine göre listele

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    Öğe
    Association between cupular deposits and otosclerosis
    (Amer Medical Assoc, 2006) Hayashi, Hideo; Cüreoǧlu, Sebahattin; Schachern, Patricia A.; Oktay, Mehmet Faruk; Fukushima, Hisaki; Sone, Michihiko; Paparella, Michael Mauro; 0000-0001-9220-7073; 0000-0001-7380-610X
    Objective: To evaluate whether otosclerosis is an underlying mechanism for the production of cupular deposits and to study the association between cupular deposits and dysequilibrium in otosclerosis. Design: Retrospective human temporal bone (TB) study. The incidence of cupular deposits in these 70 TBs was analyzed. Correlations between cupular deposits and vestibular symptoms, endosteal involvement of the otosclerotic focus, stapedial fixation, and clinical history of stapes surgery were evaluated. Setting: Otolaryngology laboratory in a tertiary academic medical center. Patients: The study material consisted of 35 human TBs with otosclerosis and 35 age-matched controls. Main Outcome Measures: Morphometric evaluations of the incidence of cupular deposits, endosteal involvement of the otosclerotic focus, and stapedial fixation were made by light microscopy. Clinical records were reviewed retrospectively for clinical history of stapes surgery and prevalence of vestibular symptoms. The incidence of cupular deposits was compared between the otosclerotic and control groups. Correlations between cupular deposits and vestibular symptoms, endosteal involvement of the otosclerotic focus, stapedial fixation, and clinical history of stapes surgery were evaluated in the subjects with otosclerosis. Results: The incidence of cupular deposits in TBs with otosclerosis was significantly higher than in those without whereas there was no correlation between the incidence of the deposits and dysequilibrium in cases of otosclerosis. An increase in deposits did not correlate with stapedial fixation, stapes surgery, or endosteal involvement. Conclusions: Our results suggest otosclerosis as an underlying mechanism for the production of cupular deposits; however, we did not find an association between these deposits and vestibular symptoms.
  • Küçük Resim
    Öğe
    Facial neuroma in the internal auditory canal
    (2000) Mutlu, Cemil; Djeric, Dragoslava R.; Tekin, Muhammet; Paparella, Michael Mauro; Schachern, Patricia A.
    Authors presented two cases of facial neuromas in the internal auditory canal, one without facial palsy and the other with facial palsy. In both cases neuromas were occult and undiagnosed. Although in the first case neuroma was greater than the other, facial palsy was not developed. The mechanism of the facial palsy due to neuromas could not be clearly clarified.
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    Öğe
    İnsan temporal kemik laboratuvarı prosedürleri:Genel bir bakış
    (2006) Oktay, Mehmet Faruk; Cüreoğlu, Sebahattin; Schachern, Patricia A.; Paparella, Micheal M.
    İnsan kulağındaki yapılar genellikle yaşam boyunca "erişilemez" özellikte olup, altta yatan hastalıklara ait patolojik değişikliklerin incelenebilmesi postmortem çalışmalarla mümkün olabilmektedir. İnsan temporal kemik (İTK) laboratuvarları bu açıdan eşsiz bir materyal kaynağı sunarlar. Bu laboratuvarlar, temporal kemik kesitlerindeki histolojik bulgularla hastanın ölmeden önceki kulak patolojisinin karşılaştırılmasına, hastalıklı olguları diğer olgularla karşılaştırmaya ve elde edilen bilgilerin diğer laboratuvarlarla paylaşılmasına olanak verir. Bu makalede insan temporal kemik laboratuvarlarının işlevinin tanıtılması amaçlandı ve yapılan histopatolojik işlemlerin ayrıntılı analiziyle birlikte bu laboratuvarlar hakkında genel bir bakış açısı sunuldu.