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Öğe Brucellosis in pregnancy(Royal Soc Medicine Press Ltd, 2011) Gulsun, Serda; Aslan, Selda; Satici, Omer; Gul, TalipThis study was undertaken in order to evaluate the effect of brucellosis in pregnancy. The serum agglutination test, Coombs and/or blood culture systems were used in the diagnosis of brucellosis. From July 2003 to September 2010, the clinical and delivery patterns of 40 healthy pregnant women were compared with 39 pregnant women who had brucellosis. There were no birth defects, anomalies or mortalities. We observed that brucellosis in pregnancy increases the incidence of preterm delivery (P = 0.01) and low birth weight (P = 0.001) from that seen in general deliveries. A cephtriaxone/rifampicin combination was found to be the most effective treatment in pregnant women infected with brucellosis (P = 0.004). Brucellosis in pregnancy has no effect on the incidence of congenital malformations or stillbirths. Preterm delivery and low birth weight can be seen as pregnancy outcomes in brucellosis. Appropriate antimicrobial therapy of brucellosis in pregnancy will reduce morbidity and prevent complications.Öğe Comparative Evaluation of Antimicrobial Efficacy and Fluoride Release of Seven Different Glass-Ionomer-Based Restorative Materials(Quintessence Publishing Co Inc, 2020) Sagmak, Savas; Bahsi, Emrullah; Ozcan, Nida; Satici, OmerPurpose: The aim of this study was to evaluate one high-viscosity glass-ionomer cement (EQUIA/GC), two resin-modified glass ionomers (Fuji II LC/GC, Photac Fil Quick Aplicap/3M Oral Care), two traditional glass ionomers (Ketac Molar Easymix/3M, Fuji II/GC), and two compomers (Freedom/SDI, Dyract XP/Dentsply Sirona) through a comparison of fluoride release and antimicrobial effects. Materials and Methods: A total of 210 samples were prepared, as 10 for each of the 7 materials for fluoride release and 20 for each material for the antimicrobial effect tests. To measure fluoride release, 5 ml distilled water and 5 ml TISAB II were added to the samples, which were then incubated at 37 degrees C. The fluoride levels of the material were measured using the selective ion electrode on days 1, 3, 7, 14 and 28. To compare the antimicrobial effects, 20 samples were divided in two groups and implanted in culture media containing Streptococcus mutans and Lactobacillus acidophylus. Measurements were taken on days 2, 4 and 6. The diameter of the inhibition zone was recorded in millimetre (mm). Results: All the materials released fluoride and the difference between them was determined to be statistically significant (p < 0.01). The antimicrobial effect values of the materials against S. mutans and L. acidophylus were evaluated and statistically significant difference was determined between the materials on all the measurement days. Conclusions: All the materials were observed to release fluoride. With the exception of the compomers, all the other materials showed an antimicrobial effect against S. mutans and L. acidophylus.Öğe Do ozone and boric acid affect microleakage in class V composite restorations?(Taylor & Francis Inc, 2019) Cangul, Suzan; Yildirim, Zehra Susgun; Bahsi, Emrullah; Sagmak, Savas; Satici, OmerThe aim of this in vitro study was to evaluate the effects of chlorhexidine gluconate (2%), sodium hypochloride (2.5%), ozone gas, and boric acid at different concentrations (1%, 3%, 5%, and 7%) on microleakage from composite restorations.In a total of 80 extracted human canine teeth, a class V cavity was opened on the buccal surface and the samples were separated into eight groups. In the control group, no procedure was applied for cavity disinfection, then composite restoration (Z250, 3M) was made using single-stage, self-etch adhesive (Single Bond 3M). In the other groups, seven different disinfectants were used, then the cavity was restored. The teeth were split into two in the buccolingual direction, parallel to the long axes. Stain penetration was examined under stereomicroscope and scored. Examination with SEM was made on one sample from each group, selected at random. Statistical evaluations were made using Dunnett C Post Hoc Comparison and Kruskal-Wallis H tests.In the occlusal region evaluation, the groups with the lowest level of leakage were the 3% and 5% boric acid groups, and the highest levels of microleakage were determined in the chlorhexidine group and the 1% boric acid group. In the gingival region, the lowest level of microleakage was in the 5% boric acid group and the highest levels were determined in the 1% and 7% boric acid groups.Boric acid disinfectants used at suitable concentrations were not seen to create a risk in respect of microleakage.Öğe Epidemiology of Cases with Rabies-Suspected Animal Contact and the Evaluation of Post Exposure Prophylaxis(Ortadogu Ad Pres & Publ Co, 2012) Gulacti, Umut; Ustun, Cemal; Gurger, Mehtap; Sahan, Mustafa; Satici, OmerObjective: This study aims to evaluate the epidemiology of cases with rabies-suspected animal contact (RSAC) and the appropriateness of rabies post-exposure prophylaxis (RPEP). Material and Methods: This retrospective study was carried out at the emergency departments of two general hospitals between January 2010 and August 2011. The management charts of cases with RSAC who were admitted to the emergency room were reviewed. Statistical analysis of data was done using SPSS for Windows (version 16.0). Results: Of 616 study cases, 464 (75.3%) were male and 152 (24.7%) were female. Cases in the subgroup aged 6-15 years had the highest risk for RSAC. Four hundred and thirty one (70%) cases lived in an urban area, and most cases had presented in the spring (36.9%) and summer (31.3%). Dogs were the most common animal (66.9%) causing RSAC with statistical significance (p=0.001). Bite was the most common way of contact with 454(73.7%) cases reaching statistical significance (p=0.001). Of 616 animals responsible for RSAC, 336 (54.6%) had no owner, while the others (280, 45.4%) had owners. RPEP was considered inappropriate in 529 (85.9%) cases according to the Rabies Prevention and Control Guidelines of the Ministry of Health, with statistical significance (p=0.001). The most frequent inappropriate procedure was the lack of rabies immunoglobulin administration in 303 (57.3%) cases. Conclusion: RSAC is an important public health problem in our region. There are some problems in the application of Rabies Prevention and Control Guidelines of the Ministry of Health and this guideline should be updated. Routine training of healthcare workers may be an effective solution against rabies.Öğe Factors Affecting the Postsurgical Length of Hospital Stay in Patients with Breast Cancer(Aves, 2015) Gumus, Metehan; Satici, Omer; Ulger, Burak Veli; Oguz, Abdullah; Taskesen, Fatih; Girgin, SadullahObjective: Breast cancer is the most common malignancy and the most common cause of mortality in women worldwide. In addition to the increasing incidence of breast cancer, the length of hospital stay (LOS) after breast cancer surgery has been decreasing. Because LOS is key in determining hospital usage, the decrease in the use of hospital facilities may have implications on healthcare planning. The purpose of this study was to evaluate the factors affecting postoperative LOS in patients with breast cancer. Materials and Methods: Seventy-six in patients with breast cancer, who had been treated between July 2013 and December 2014 in the General Surgery Clinic of Dicle University, were included in the study. The demographic characteristics of the patients, treatment methods, histopathological features of the tumor, concomitant diseases, whether they underwent neoadjuvant chemotherapy or not, and the length of drain remaining time were retrospectively recorded. Results: There was a correlation between drain remaining time, totally removed lymph node, the number of metastatic lymph node, and LOS. LOS of patients treated with neoadjuvant chemotherapy was longer. The patients who underwent breast-conserving surgery had a shorter LOS. Linear regression analysis revealed that the drain remaining time and the number of metastatic lymph nodes were independent risk factors for LOS. Conclusion: Consideration should be given to cancer screening to diagnose the patients before lymph node metastasis occurs. In addition, drains should be avoided unless required and, if used, they should be removed as early as possible for shortening LOS.Öğe The levels of copper, zinc and magnesium in type II diabetic patients complicated with foot infections(Springer India, 2013) Bozkurt, Fatma; Tekin, Recep; Gulsun, Serda; Satici, Omer; Deveci, Ozcan; Hosoglu, SalihChanges in levels of trace elements and magnesium (Mg) may contribute to progression of diabetes mellitus (DM) and development of the complications. The aim of this study was to measure the levels of Copper (Cu), Zinc ( Zn), Mg and Cu/Zn ratios in diabetic foot infected patients (DFI) compared to controlled diabetic patients and healthy controls. 50 patients complicated with DFI, 50 controlled diabetic patients without any complications and 100 age and sex matched healthy subjects were enrolled in the study. Fasting plasma glucose, HbA1c, Cu, Zn and Mg were measured. One-Way ANOVA test was used to compare three different groups. Correlations between different variables were analysed using Pearson's correlation coefficients(r). The mean values of Cu and Zn were higher in patients with DFI and DM compared to controls (P < 0.001). Cu/Zn ratios were higher in DM compared to DFI and control groups (P < 0.001). Serum Mg levels were lower in all diabetic patients. Elevation of Cu in DFI and DM groups was positively correlated with Cu/Zn ratios and elevation of Zn is negatively correlated. Our findings indicate an association between increased Zn concentrations and DFI.Öğe Prognostic Value of Preoperative CEA and CA 19-9 Levels in Patients with Colorectal Cancer(H G E Update Medical Publishing S A, 2011) Basbug, Murat; Arikanoglu, Zulfu; Bulbuller, Nurullah; Cetinkaya, Ziya; Aygen, Erhan; Akbulut, Sami; Satici, OmerAims: This study evaluated the prognostic value of the preoperative CEA and CA 19-9 levels on the survival time and TNM staging in patients with colorectal cancer. Methodology: We retrospectively analyzed 172 patients who underwent potentially curative resection of colorectal cancer (TNM I-III) between 2002 and 2007. Clinical data were obtained from medical charts, including age, gender, tumor location, TNM stage, mortality, follow-up duration, and preoperative CEA and CA 19-9 levels. A CEA >= 5ng/mL was defined as abnormal (CEA+), while the cutoff for the CA19-9 was set at 37U/mL (CA19-9+). Patients were categorized into Groups I-IV according to the preoperative serum CEA and CA 19-9 levels [CEA/CA 19-9: (-/-), (+/-), (-/+), and (+/+)]. Results: Follow-up was longest for Group I (p<0.001). Mortality rates were higher in Groups V' (p<0.001) and II (p<0.008). On comparing patients according to CEA levels, survival was longer in the CEA-negative group (p=0.0001). On comparison according to CA 19-9 levels, survival was greater in the CA 19-9-negative group (p=0.0001). While CEA (p<0.016) and CA 19-9 (p<0.001) were independent prognostic factors according to the logistic regression analysis, TNM (p=0.002), CEA (p<0.001), and CA 19-9 (p<0.001) were prognostic factors in the ROC curve analysis. Conclusions: Colorectal cancer patients with elevated levels of both CEA and CA 19-9 have a significantly poorer prognosis than those with normal levels of these tumor markers.Öğe Radical vs conservative surgery for hydatid liver cysts: Experience from single center(Baishideng Publishing Group Inc, 2010) Akbulut, Sami; Senol, Ayhan; Sezgin, Arsenal; Cakabay, Bahri; Dursun, Mehmet; Satici, OmerAIM: To compare the efficacy and safety of radical and conservative surgical interventions for liver hydatid disease. METHODS: The study comprised 59 patients in two groups who had undergone radical and conservative surgical procedures for liver hydatid disease in our department between 2004 and 2009. Preoperative diagnostic tools, medical treatments, demographic and clinical characteristics, postoperative follow-up, and recurrence were compared in both groups. RESULTS: This non-randomized retrospective study included 59 patients who had undergone liver hydatid disease surgery. The radical technique was used in 18 patients (mean age: 42.1 +/- 13.5 years, seven male, 11 female), and the conservative technique was used in 41 patients (mean age: 43.5 +/- 13.9 years, 17 male, 24 female). The follow-up period ranged from 3 to 58 mo. Although operative time was significantly shorter in the conservative group (P < 0.001), recurrence was significantly reduced in the radical group (P = 0.045). No statistically significant differences were found in terms of hospitalization duration, cyst count and size, location, postoperative complications, scolicidal solution usage, or follow-up duration between the two groups. CONCLUSION: The more effective method for preventing postoperative recurrence is radical surgery. Endoscopic retrograde cholangiopancreatography for bile leakage in the early postoperative period may decrease the requirement for repeat surgery. (C) 2010 Baishideng. All rights reserved.Öğe RADIOLOGICAL DAMAGE IN RHEUMATOID ARTHRITIS: RELATIONSHIP BETWEEN THE DURATION OF MORNING STIFFNESS, DEPRESSIVE SYMPTOMS, AND DISEASE DURATION(Carbone Editore, 2015) Celepkolu, Tahsin; Sariyildiz, Mustafa Akif; Yazmalar, Levent; Bucaktepe, P. Gamze Erten; Cetincakmak, Mehmet Guli; Satici, OmerAims: The aim of this study was to evaluate radiological damage and disease-related variables in patients with rheumatoid arthritis (RA). Material and methods: Ninety patients diagnosed with RA were enrolled in this cross-sectional and descriptive study. All of the patients were assessed using the Rheumatoid Arthritis Quality of Life and Health Assessment Questionnaire scales and the Beck Depression Inventory. The Disease Activity Score 28 scale was used to assess disease activity, and antibodies against mutated citrullinated vimentin (Anti MCV) were identified with an Enzyme-Linked Immuno Sorbent Assay. Radiological damage was calculated with the modified Larsen method. Results: According to the suggested Cut-off point for the Larsen score (scores >= 28), 35.5% (n=32) of the patients with RA had an erosive score. The patients with erosive RA had significantly higher Anti MCV, disease duration and Beck depression scores than did the non-erosive RA group. Multivariate regression analyses indicated that the Beck depression score, disease duration and duration of morning stiffness were independently associated with the radiological score. Conclusion: Radiological damage in RA patients is a result of multifactorial origins and is associated with disease-related variables such as disease duration, duration of morning stiffness, Anti- Cyclic citrullinated peptide levels and depressive symptoms.Öğe The reproductive biology of Carasobarbus luteus and Capoeta trutta in the Tigris River, Turkey(Soc Francaise D Ichtyologie, 2016) Bilici, Serbest; Unlu, Erhan; Cicek, Tarik; Satici, OmerThis study was carried out to determine the reproductive characteristics of two species of Cyprinidae, Longspine scraper, Capoeta trutta (Heckel, 1843) and Mesopotamian himri, Carasobarbus luteus (Heckel, 1843) in the Tigris River of Turkish part. A total of 307 C. luteus (138 females and 169 males) and 394 C. trutta (269 females and 125 males) specimens were analyzed. The sex ratio for C. luteus and C. trutta was 1:1.22 females (44.95%) to males (55.05%) and 1:0.47 females (68.27%) to males (31.73%), respectively. The reproduction period was between May and July for both species. The water temperature at this period was between 21.4 degrees C and 31 degrees C. Results indicated that the age at first maturity in C. luteus was three years for both males and females, and in C. trutta, three years for females and two years for males. The mean estimated fecundity was 5843 +/- 3554 for C. luteus and 5285 +/- 3105 for C. trutta. Maximal egg diameter for C. luteus and C. trutta were 1.61 +/- 0.45 mm and 0.91 +/- 0.41 mm, respectively.Öğe The role of trace elements in wagner classified diabetic patients(Academic Journals, 2011) Bozkurt, Fatma; Gulsun, Serda; Ustun, Cemal; Geyik, M. Faruk; Tegin, Ibrahim; Satici, OmerWagner's classification is the most widely used grading system in diabetic foot infections. The aim of this study was to evaluate the role of the trace elements in diabetic foot infected patients graded with Wagner's classification. This prospective study was carried out on 50 diabetic patients with variable severity of foot infections and 50 age and sex matched healthy subjects in Dicle University, Turkey, between October 2006 and November 2008. Diabetic foot infections were graded according to Wagner classification and deep tissue cultures were performed from all diabetic foot infected patients. The atomic absorption spectrophotometer was used in the measurement of trace elements in the serum. serum zinc and copper levels were significantly elevated in patients with Wagner 3 and 4 compared to Wagner 2 and 1 graded patients and healthy controls. Also Wagner 1 and 2 graded patients had higher serum zinc levels compared to healthy controls (p < 0.001). This study confirms that trace elements may be used as a leading sign to determine the severity of infections in diabetic foot wounds and may be used to predict outcome of diabetic foot infections.Öğe Serum neuron-specific enolase as a predictor of short-term outcome and its correlation with Glasgow Coma Scale in traumatic brain injury(Springer, 2008) Guzel, Aslan; Er, Uygur; Tatli, Mehmet; Aluclu, Ufuk; Ozkan, Umit; Duzenli, Yucel; Satici, OmerElevated serum neuron-specific enolase levels are correlated with brain cell damage. Low scores according to Glasgow Coma Scale are also considered as serious poor prognostic factor. The aims of the study were to investigate whether there is a correlation between the two measurements in patients with traumatic brain injury and whether serum neuron-specific enolase levels have potential as a screening test to predict outcome. A total of 169 consecutive patients with traumatic brain injury admitted to our clinic between 2002 and 2005 are included in this study. Those patients, who had any major health problem before trauma, were excluded from the study. However, patients with isolated head injury were included in the study. Serial serum neuron-specific enolase concentrations taken at the first 2, 24, and 48 h after traumatic brain injury were analyzed. A computed tomography was performed on each patient on admission. Their Glasgow Coma Scale scores were recorded serially. The relationship between Glasgow Coma Scale scores and the serum neuron-specific enolase levels were assessed by statistical methods. There was a significant negative correlation between the serum neuron-specific enolase levels and Glasgow Coma Scale scores. The levels of neuron-specific enolase were significantly higher in the patients who died in 30 days after trauma and whose scores were lower than or equal to 8 points in Glasgow Coma Scale. Although there are several serious limitations of the use of neuron-specific enolase as a biomarker in traumatic brain injury (i.e., hypoperfusion, extracranial trauma, bleeding, liver, or kidney damage also increase the level of neuron-specific enolase), its concentrations may be useful as a practical and helpful screening test to identify neurotrauma patients who are at increased risk and may provide supplementary estimation with radiological and clinical findings.