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    Massive Pulmonary Embolism with Mobile Right Atrial Thrombus in a Pregnant Patient Using Valproic Acid
    (Aves, 2012) Soydinc, Hatice Ender; Yuce, Murat; Sari, Emine; Yavuz, Sema; Sari, Ibrahim; Davutoglu, Vedat; Yigiter, Remzi
    Pulmonary embolism is a life threatening condition. Pregnancy is among the risk factors of pulmonary embolism. There is reluctance about using thrombolytics s during pregnancy due to potential teratogenic effects. Valproic acid is one of the most commonly used antiepileptic agents, hovewer, its use during pregnancy is controversial because of the teratogenic potential. Among adverse effects of valproic acid use, elevated liver enzymes, thrombocytopenia have been reported. Moreover, product literature warns that pregnant women using valproic acid should be monitored for low fibrinogen and platelets and the potential for bleeding. The present case report describes successful treatment of a massive pulmonary embolism with tissue plasminogen activator (t-PA), caused by a mobile right atrial thrombus in a 30-year-old first trimester pregnant women using valproic acid. This has not been reported previously. During follow-ups, she was free of any signs or symptoms and gave birth to a baby by spontaneous vaginal delivery. The baby was completely healthy without any problem or deformity.
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    Staphylococcus Hominis Native Tricuspid Valve Endocarditis Following Spontaneous Abortus
    (Emergency Medicine Physicians Assoc Turkey, 2012) Soydinc, Hatice Ender; Yuce, Murat; Sari, Emine; Sari, Ibrahim; Yildirim, Cuma; Davutoglu, Vedat; Ercan, Suleyman
    The patient had a spontaneous abortion in the fifth week of her pregnancy and had nonspecific treatment due to fever and chills that had started 3 days after the spontaneous abortion. She was diagnosed and treated as endocarditis as there was vegetation on the tricuspid valve on transthoracic echocardiography, and blood culture revealed Stphylococcus Hominis. The patient completely recovered from endocarditis after antibiotic treatment and had another pregnancy ending with normal birth without any complication. Stphylococcus Hominis is a coagulase negative microorganism that normaly exists in skin flora, causing endocarditis more commonly in immunesup-pressed subjects, patients with prosthetic valves and acessory devices. Here in this case report, we present a 31 year-old woman who had the complication of native tricuspid valve endocarditis after spontaneous abortus in her fifth week of pregnancy. To our knowledge, the present case is the first to be reported as a native valve endocarditis caused by Stphylococcus Hominis associated with pregnancy or abortus.