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    Öğe
    Efficacy of topical cyclosporin A 0.05% in conjunctival impression cytology specimens and clinical findings of severe vernal keratoconjunctivitis in children
    (Springer Tokyo, 2008) Keklikci, Ugur; Soker, Sevda I.; Sakalar, Yildirim B.; Unlu, Kaan; Ozekinci, Selver; Tunik, Selcuk
    To evaluate the efficacy of topical cyclosporin A 0.05% in managing the symptoms of severe vernal keratoconjunctivitis (VKC). Fifty-four children with severe VKC were included in this study. All 54 patients were treated with topical cyclosporin A (CsA) 0.05% for 3 months. Ocular signs and symptoms were scored in all patients at entry and after 3 months. Conjunctival impression cytology specimens were examined on the day of enrollment and at the end of the treatment period. The mean scores for severity of signs and symptoms significantly decreased after 3 months compared with those at entry (P < 0.001). The density of inflammatory cells in the conjunctival impression cytology specimens decreased significantly. No side effects of the treatment with CsA 0.05% eyedrops were observed. Topical CsA 0.05% eyedrops were found to be safe and effective in the treatment of patients with VKC. Consistent with these results, topical CsA may efficiently reduce conjunctival inflammation in severe VKC.
  • [ X ]
    Öğe
    Evaluation of Perforating Eye Injuries by Using Cluster Analysis
    (Amer Soc Contemporary Medicine Surgery & Ophthalmology, 2008) Keklikci, Ugur; Celik, Yusuf; Cakmak, Sevin Soker; Sakalar, Yildirim B.; Unlu, M. Kaan
    We evaluated the epidemiology, visual outcome, and clinical characteristics of serious eye injuries and identified preventable risk factors. We concluded that many accidents and their resulting injuries were preventable by education, greater intensive care and workplace safety. Perforating ocular injuries in rural environment are still a big therapeutic, social and economic problem.