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    Öğe
    Cleidocranialdysplasia. Amolecularandclinicalreview
    (2018) Fortunato, Leonzio; Yavuz, İzzet; Plotino, Gianluca; Avendano, Andrea; Callea, Michele; Grande, Nicola Maria; Rizal, Mochamad Fahlevi
    Cleidocranial dysplasia (CCD) is a rare autosomal dominant disorder characterized by skeletal and dental abnormalities primarily, short stature, aplasia or hypoplasia of clavicles, open fontanelles and supernumerary teeth. Heterozygous mutations of the runt-related transcription factor 2 (RUNX2) gene have been found in approximately 60-70% of cases,leaving a large number of cases with no defined genetic cause which ledus to delve into molecular mechanisms underlying CCD and thus to detect potential target genes to be explored in these patients. In this review,we also highlight very broadly the phenotypic characteristics of previously reported patients with CCD.
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    Öğe
    Micro-shear bond strength of different calcium silicate materials to bulk-fill composite
    (PeerJ Inc., 2023) Falakaloğlu, Seda; Özata, Merve Yeniçeri; Plotino, Gianluca
    Introduction: This study aimed to compare the micro-shear bond strength (µSBS) performances of two resin-based calcium silicate-based cement (CSC) (TheraCal PT and TheraCal LC), Biodentine, and two modified-MTA CSC materials (NeoMTA 2 and BioMTA+) to bulk-fill restorative material. Materials and Methods: Fifty 3D printed cylindrical resin blocks with a central hole were used (2 mm in depth and 4 mm in diameter). CSCs were placed in the holes (per each group n = 10) and incubated for 24 h. Cylindrical polyethylene molds (2 mm in height and diameter) were used to place the bulk-fill restorative materials on the CSCs and polymerize for 20 s. Then, all specimens were incubated for 24 h at 37 °C at a humidity of 100%. Specimen’s µSBSs were determined with a universal testing machine. Data were analyzed with one-way ANOVA (Welch) and Tamhane test. Results: Statistically higher µSBS was found for TheraCal PT (29.91 ± 6.13 MPa) (p < 0.05) respect to all the other materials tested. TheraCal LC (20.23 ± 6.32 MPa) (p > 0.05) reported higher µSBS than NeoMTA 2 (11.49 ± 5.78 MPa) and BioMTA+ (6.45 ± 1.89 MPa) (p < 0.05). There was no statistical difference among TheraCal LC, NeoMTA 2 and Biodentine (15.23 ± 7.37 MPa) and between NeoMTA 2 and BioMTA+ (p > 0.05). Conclusion: Choosing TheraCal PT as the pulp capping material may increase the adhesion and µSBS to the bulk-fill composite superstructure and sealing ability.
  • Küçük Resim
    Öğe
    The micro-shear bond strength of new endodontic tricalcium silicate-based putty: An in vitro study
    (John Wiley and Sons Inc, 2023) Özata, Merve Yeniçeri; Falakaloğlu, Seda; Plotino, Gianluca; Adıgüzel, Özkan
    This study aimed to compare in vitro micro-shear bond strength (μSBS) of three different endodontic tricalcium silicate-based materials in contact with a bulk-fill resin-based composite. Thirty cylindrical resin blocks with a hole in the centre (2 mm in depth and 4 mm in diameter) were manufactured with a 3D printer and divided into three groups (n = 10), depending on the calcium silicate cement used: light curing TheraCal LC (Bisco, Schaumburg, IL, USA), liquid–powder NeoMTA 2 (NuSmile Avalon Biomed, Bradenton, FL, USA) and putty NeoPutty (NuSmile, Houston, TX, USA). Each sample was stored for 24 h at 37°C and 100% humidity. Then, after adhesive placement, the restorative material Filtek bulk-fill (3 M ESPE, St. Paul, MN, USA) was placed over the capping material using cylindrical plastic capsules (2 mm height and 2 mm) and polymerised for 20 s. Specimens were then tested in a universal testing machine for the compression load resulting in the μSBS. The data were compared with the one-way ANOVA (Welch) and the Tamhane test. The mean value was significantly higher in the TheraCal LC group than in the other two groups (p < 0.05). There was no significant difference between NeoMTA 2 and NeoPutty groups (p > 0.05). The majority of failure modes for all groups were cohesive within biomaterial. Using TheraCal LC in the pulp capping procedure can result in higher bond strength values to the tested bulk-fill resin-based composite than NeoMTA 2 and NeoPutty.