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    Multiple Circumferential Urethrocutaneous Fistulae as a Rare Complication of Circumcision and Review of Literature
    (Elsevier Science Inc, 2011) Sancaktutar, Ahmet Ali; Pembegul, Necmettin; Bozkurt, Yasar; Kolcu, Bayram; Tepeler, Abdulkadir
    Circumcision remains the most common surgical procedure performed in boys worldwide. Although circumcision can be associated with numerous major and minor complications, urethrocutaneous fistula is extremely rare and serious. An 18-years-old boy presented with urine passage from 4 fistula orifices. He had been circumcised by nonmedical personnel when he was 2 years old. During the surgery, after degloving the penis, it was observed that the fistulae tracts werecombining. There were only 2 fistulae orifices on the urethra. The fistulae were repaired with simple closure. This is the second case reported in the literature describing multiple urethrocutaneous fistulae. UROLOGY 77: 728-729, 2011. (C) 2011 Elsevier Inc.
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    The Protective Effect of Ellagic Acid Against Renal Ischemia-Reperfusion Injury in Male Rats
    (Kafkas Univ, Veteriner Fakultesi Dergisi, 2012) Bozkurt, Yasar; Firat, Ugur; Atar, Murat; Sancaktutar, Ahmet Ali; Pembegul, Necmettin; Soylemez, Haluk; Yuksel, Hatice
    The aim of this study was to evaluate the possible protective effect of ellagic acid (EA) on rats following renal ischemia reperfusion (I/R) injury. Twenty-four Wistar rats were divided into three groups. Sham group underwent laparotomy then waited for 45 min without ischemia. I/R group were subjected to left renal ischemia for 45 minutes followed by 60 min of reperfusion. I/R+EA group were subjected to the same renal ischemia/reperfusion as the I/R group, were also given 85 mg/kg EA perorally 30 min prior to the ischemia. Malondialdehyde (MDA), total antioxidant capacity (TAC), total oxidant status (TOS), and oxidative stress index (OSI) were determined on the blood samples and kidney tissues. Histopathological analyses were conducted on the kidney tissues. I/R damage significantly increased serum MDA levels in the I/R group when compared with Sham group. Serum TAC level was significantly lower in I/R group than I/R+EA group. A significantly increase on OSI levels and decrease on TAC levels was found in the kidneys in I/R group. In I/R + EA group, EA reversed the negative effects of I/R injury. EA pretreatment was effective in decreasing tubular necrosis score. In conclusion; EA pretreatment ameliorated the oxidative damage and histopathological changes occurring following renal I/R injury.