Yazar "Ozhan, Hakan" seçeneğine göre listele

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    Epidemiology of atrial fibrillation in Turkey: preliminary results of the multicenter AFTER study Reply
    (Turkish Soc Cardiology, 2013) Ertas, Faruk; Kaya, Hasan; Ozhan, Hakan
    [Abstract Not Available]
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    Normal range of mean platelet volume in healthy subjects: Insight from a large epidemiologic study
    (Pergamon-Elsevier Science Ltd, 2011) Demirin, Hilmi; Ozhan, Hakan; Ucgun, Taner; Celer, Ahmet; Bulur, Sule; Cil, Habip; Gunes, Cemalettin
    Aim: Mean platelet volume (MPV) in the healthy population has not been studied before. Therefore, the aim of the study was to measure MPV in normal subjects in a large cohort of Turkish adults. Methods: A total of 2298 subjects with a mean age of 50 (age range 18 to 92) were interviewed. Subjects who had smoking habit, diabetes, hypertension, coronary artery disease, dyslipidemia, chronic obstructive pulmonary disease, cancer, chronic use of any drugs including antiplatelets, heavy drinkers, metabolic syndrome, ejection fraction < 55%, creatinine > 1.4 in men and > 1.1 in women, abnormal liver function tests and an abnormal TSH were excluded in a in a stepwise manner. Complete blood counts were done on the same day within 6 hours by a CELL-DYN 3700 SL analyzer (Abbott Diagnostics). Results: Three hundred twenty-six participants (204 females (63%) and 122 males (37%) with a mean age of 41 +/- 16) constituted the final healthy cohort. Mean MPV of the cohort was 8.9 +/- 1.4 fL. There was no significant difference among age groups regarding MPV. Conclusion: Ninety-five percent of the individuals had a MPV between 7.2 and 11.7 fL. A patient having a MPV beyond this range should be evaluated carefully especially for occlusive arterial diseases. (C) 2011 Elsevier Ltd. All rights reserved.
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    PREDICTORS OF SUBCLINICAL ATHEROSCLEROSIS IN PREMENOPAUSAL WOMEN
    (Carbone Editore, 2014) Aydin, Mesut; Alemdar, Recai; Cil, Habib; Besir, Fahri Halit; Ozhan, Hakan; Aydin, Yusuf; Bulur, Serkan
    Aims: We aimed to investigate the predictors of Carotid intima media thickness (CIMT) in premenopausal women. Background: CIMT was shown to be a strong coronary artery disease predictor in both pre- and postmenopausal women. Materials and methods: The study was conducted on 2298 participants. The final cohort included 783 pre-menopausal women (with a mean age of 39 +/- 11). Carotid intima media thickness was measured in all of the participants. Results: Mean CIMT of premenopausal women was 0.51 +/- 0.14 mm. Age- adjusted correlates of CIMT was SBP (r = 0.138; p=<0.001), DBP (r=0.095; p=-0.012) and LDL/HDL (r =0.077; p=0.041) ratio. Linear regression analysis was done in order to find independent covariates of carotid intima media thickness in two different models. Only age and systolic blood pressure were independently associated with CIMT. Logistic regression analysis revealed that only age was an independent predictor of subclinical atherosclerosis. Hypertension had the highest Odds ratio with borderline significance. Conclusion: The age and systolic blood pressure were independently associated with CIMT in premenopausal healthy Turkish women. Hypertension might be the best target for a modifiable risk factor for CIMT and future cardiovascular risk in this population.