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  • [ X ]
    Öğe
    Female suicides in Diyarbakir, Turkey
    (Wiley, 2004) Goren, S; Subasi, M; Tirasci, Y; Ozen, S
    The aim of this study was to investigate the methods used and demographic data of women suicides by examining postmortem investigation and autopsy reports from the Branch of the Council of Forensic Medicine in Diyarbakir Province, Turkey, between 1996 and 2001. Fifty-eight percent (174/302) of suicides were females and 42% (128/302) were males. The suicide rates were similarly higher for females than for males (2.6 and 1.8 per 10,000 population, respectively). Over half of female suicides (56.3%) occurred in those under 20 years of age. The most common suicide method for women was hanging (32.2%), and for men was firearms (51.7%), but for women younger than 20 years the most frequent method was firearms. Among the female suicides, five (2.8%) were known to have attempted suicide at least once in the past. Twenty-nine women (16.7%) were documented to have any psychiatric illness. None of the women had a history of drug or alcohol abuse. A suicide note was found in only six cases (3.4%). The predominant suicide motive was family problems (in 32% or 56/174). The higher rate of suicide in females than in males, and the absolute female predominance in suicides in Diyarbakir, Turkey, are in contrast to most of the medical literature and statistical information about suicide rates by country, in which suicide rates are usually higher among males.
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    Öğe
    Frequency of PTSD in a group of search and rescue workers two months after 2003 Bingol (Turkey) earthquake
    (Lippincott Williams & Wilkins, 2004) Ozen, S; Sir, A
    This study aimed to determine the frequency of posttraumatic stress disorder (PTSD) in a group of search and rescue workers 2 months after the May 2003 Bingol earthquake. Forty-four of 55 workers were interviewed. The Personal Information Form, the Clinician Administered Posttraumatic Stress Disorder Scale, the State Anxiety Inventory, the Trait Anxiety Inventory, the Beck Depression Inventory, the Quality of Life Enjoyment and Satisfaction Questionnaire, and the Endicott Work Productivity Scale were used. PTSD was diagnosed in 25% of the subjects. In subjects with PTSD, all scale scores were significantly higher. A positive correlation was determined between Clinician Administered Posttraumatic Stress Disorder Scale score and State Anxiety Inventory, Trait Anxiety Inventory, Beck Depression Inventory, Endicott Work Productivity Scale scores (r = 0.712, p = .000; r = 0.429, p = .004; r = 381, p = .011; r = 0.720, p = .000, respectively). The high scores of all scales showed that PTSD may also have comorbidity with other psychiatric disorders. Rescue workers who give first-level service in disasters should receive psychiatric support in specific time frames.
  • [ X ]
    Öğe
    Increased oxidative stress and altered activities of erythrocyte free radical scavenging enzymes in autism
    (Springer Heidelberg, 2004) Zoroglu, SS; Armutcu, F; Ozen, S; Gurel, A; Sivasli, E; Yetkin, O; Meram, I
    There is great evidence in recent years that oxygen free radicals play an important role in the pathophysiology of many neuropsychiatric disorders. The present study was performed to assess the changes in red blood cells thiobarbituric acid-reactive substances (TBARS) levels, and superoxide dismutase (SOD), catalase (CAT), adenosine deaminase (ADA) and xanthine oxidase (XO) activities in patients with autism (n = 27) compared to age- and sex-matched normal controls (n = 26). In the autistic group, increased TBARS levels (p < 0.001) and XO (p < 0.001) and SOD (p < 0.001) activity, decreased CAT (p < 0.001) activity and unchanged ADA activity were detected. It is proposed that antioxidant status may be changed in autism and this new situation may induce lipid peroxidation. These findings indicated a possible role of increased oxidative stress and altered enzymatic antioxidants, both of which may be relevant to the pathophysiology of autism.
  • [ X ]
    Öğe
    Interferon-alpha-induced mood disorder with manic features
    (Elsevier Science Inc, 2001) Altindag, A; Ozbulut, O; Ozen, S; Ucmak, H
    [Abstract Not Available]
  • [ X ]
    Öğe
    Juvenile delinquency in a developing country: A province example in Turkey
    (Pergamon-Elsevier Science Ltd, 2005) Ozen, S; Ece, A; Oto, R; Tirasci, Y; Goren, S
    The aim of this study was to determine offence behavior, socio-demographic characteristics and some features of the juvenile offenders' families in a selected region, and compare with developed countries. A total of 165 juvenile offenders were included. Information was obtained by individually interviewing all children. Of a total of 165 juveniles, 162 (98%) were boys. The most frequently committed crimes were theft (52%) and wounding (20%). Of these juveniles, 33% were 14 years old when they committed offence, 21% had a history of an offence behavior, 14.5% had an offender sibling, 36% had smoking habits, 21% had a history of running away from home, and 28% had a history of internal migration. Mild psychiatric disorders were detected in 9 (5.4%) and 51% of them were not student at the time of offence behavior. Most of the families were crowded and had rather low economical and educational levels. Some features such as low income and low family educational levels, insufficient parental control, crowded family, migration, repetition of offences, and cigarette smoking were found to be risk factors for offensive behavior. These risk factors can be taken into consideration for the prevention of future crimes. (c) 2005 Elsevier Inc. All rights reserved.
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    Öğe
    Long-term urologic, orthopedic, and psychological outcome of posterior urethral rupture in children
    (Elsevier Science Inc, 2005) Onen, A; Subasi, M; Arslan, H; Ozen, S; Basuguy, E
    Objectives. To evaluate the long-term urologic, orthopedic, and psychological outcome of children after posterior urethral rupture (PUR) due to pelvic trauma. Methods. We retrospectively reviewed the records of 49 children with PUR from 1986 to 2000. The long-term urologic results were determined by voiding function, continence, and erectile function. The orthopedic results were determined by pelvic radiography and a questionnaire. Psychiatric diagnoses were made using the Diagnostic and Statistical Manual of Mental Disorders, 4th edition (DSM-IV), criteria and the Structured Clinical Interview for DSM-IV Axis I Disorders. Results. The mean follow-up was 12 years (range 4 to 17). The average age was 8 years at the time of the trauma and 20 years at the last follow-up. Urethral continuity was achieved in 97.9% of the children. Of the 49 patients, 19 had at least one urologic complication, 18 had orthopedic pathologic findings, and 21 had psychiatric diagnoses. The number of urologic procedures required (more than three), presence of long-term complications, and total number of hospitalizations (more than three) secondary to the injury significantly affected the development of a psychological disorder. Conclusions. The results of our study have shown that posttraumatic PUR in children is associated with a significant rate of long-term complications. Nonoperative treatment of pediatric pelvic fractures associated with PUR has been quite successful. Repeated operations, the presence of long-term urologic complications, and frequent and long hospital stays result in serious attendant psychological problems. Therefore, careful and prolonged follow-up of posttraumatic urethral injury with a multidisciplinary approach is necessary to provide better outcomes and a better quality of physical and social life for these children.
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    No evidence for an association between the T102C and 1438 G/A polymorphisms of the serotonin 2A receptor gene in attention deficit/hyperactivity disorder in a Turkish population
    (Karger, 2003) Zoroglu, SS; Erdal, ME; Erdal, N; Ozen, S; Alasehirli, B; Sivasli, E
    Disturbances in the serotonergic neurotransmission system have been implicated in the etiology of attenion deficit/hyperactivity disorder (ADHD). As the importance of genetic factors is well established, genes encoding for proteins of the serotonergic pathway are important candidates to unravel the underlying genetic contribution. We previously demonstrated that the polymorphisms of the serotonin transporter gene promoter and regions of variable number of tandem repeats were involved in the pathogenesis of ADHD. The purpose of this study was to examine the relationship between ADHD and two polymorphisms (T102C and 1438 G/A) in the 5-HT2A gene in a sample of Turkish children. Using the PCR technique, these polymorphisms were assessed in 70 patients with ADHD and in 100 healthy controls. There was no significant difference between the frequencies of the T, C, G and A alleles of both groups. No association was found between the studied polymorphisms of the 5-HT2A gene and ADHD in this sample consisting of Turkish children. Overall, our results suggest that the investigated 5-HT2A polymorphisms are not major susceptibility factors in the etiology of ADHD. Copyright (C) 2003 S. Karger AG, Basel.
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    Öğe
    One-year follow-up study of posttraumatic stress disorder among earthquake survivors in Turkey
    (W B Saunders Co, 2005) Altindag, A; Ozen, S; Sir, A
    Earthquakes and their consequences present a major global public health problem. In 1998, a major earthquake struck Southern Turkey. The aims of this study were to describe longitudinally the severity and the course of posttraumatic stress disorder (PTSD) and depression among earthquake survivors in Turkey and to explore risk factors associated with psychiatric disorders. The sample of this study consists of 105 consecutive subjects who used our psychiatric service, via either outpatient clinic or home visit. PTSD was assessed by the Clinician-Administered PTSD Scale for Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition. The severity of depression was assessed using Beck Depression Inventory. The rates of earthquake-related Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition PTSD were 42% within 1 month and 23% within 13 months. The diagnosis of PTSD was significantly related to the presence of injury and to less social support in the initial assessment. In the follow-up assessment, although the mean total Clinician-Administered PTSD Scale severity score improved significantly, the mean Beck Depression Inventory score did not change significantly. The decrease in posttraumatic stress symptoms 13 months after the earthquake may be related to relatively good living conditions and adequate social and health services. Early mental health intervention may serve to prevent the chronicity of posttraumatic stress reactions among earthquake victims. (c) 2005 Elsevier Inc. All rights reserved.
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    Öğe
    Suicide in children and adolescents at a province in Turkey
    (Lippincott Williams & Wilkins, 2003) Goren, S; Gurkan, F; Tirasci, Y; Ozen, S
    Despite the well-documented increases in the rate of completed suicide among children, accurate knowledge of the characteristics of these suicides. is limited. We examined all suicides by children and adolescents in Diyarbakir during 1999 and 2001. All of the cases were analyzed regarding the age, sex, method and location of suicide, time of year, and predictive factors. There were 56 children aged I I through 19 years. Adolescents between 15 and 19 years of age constituted the overwhelming number (87%) of all the childhood suicides. Female children and adolescents predominated among the suicide victims (71%). The most frequent means of suicide were firearms (43%), hanging (28%), and jumping (16%), respectively. The majority of suicides occurred at the decedent's home (88%). Reasons identified were mainly psychiatric disorders, followed by troubles within the family. A prior suicide attempt or a note that was left by the decedent and elucidated the reason for the suicide was rare. There was no seasonal difference in rates of suicides.

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