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    Öğe
    Predictive value of lymphocyte to monocyte ratio for cardiac syndrome X
    (Verduci Publisher, 2022) Akil, M. A.; Oylumlu, M.; Demir, M.; Ozbek, M.; Polat, N.; Acet, H.; Bilik, M. Z.
    OBJECTIVE: Cardiac syndrome X (CSX) is typically described with ischemia in stress tests in addition to angina-like chest pain and without stenosis in coronary angiography. We aimed at determining the relationship between LMR and CSX. PATIENTS AND METHODS: We retrospectively collected patients with CSX between January 2016 and December 2019. Patients with typical angina-like chest pain, normal 12-lead electro-cardiography at rest, a positive response to the exercise test (> 0.1 mV ST-segment depression at 80 ms after the J point in two or more contiguous leads) or ischemia on myocardial perfusion scintigraphy and normal coronary angiography were included in the study as CSX patients. RESULTS: This study consisted of 116 patients with CSX and 153 control groups. The mean age of the patients with CSX was 52.7 +/- 9.7 years, and the mean age of the control group was 53.7 +/- 10.6 years (p= 0.416). The patients with CSX were more likely to have higher monocyte counts and LMR. According to the Pearson correlation test, the CRP value negatively correlated with the LMR. In multivariate logistic regression analysis, LMR remained a significant predictor of CSX. In ROC analysis, LMR <4.1 had 64% sensitivity and 50% specificity (ROC area under curve: 0.587, 95% CI: 0.519-0.655, p=0.015) in accurately predicting a CSX diagnosis. CONCLUSIONS: We showed that lower LMR levels were associated with the presence of CSX.
  • [ X ]
    Öğe
    Prognostic importance of nutritional assessment in patients with acute ischemic stroke undergoing endovascular thrombectomy
    (Verduci Publisher, 2023) Ozbek, M.; Akil, M. A.; Demir, M.; Arik, B.; Demir, F.; Akil, E.
    - OBJECTIVE: The prevalence of malnutrition in patients with acute isch-emic stroke (AIS) can range from 8% to 34%. It has been shown that prognostic nutritional in-dex (PNI) and control nutritional status (CO -NUT) scores can provide an opportunity to make prognostic predictions in some disease groups. Previous studies have shown a close relationship between malnutrition scores and stroke prognosis. We evaluated the effect of nutritional scores on in-hospital and long-term mortality in AIS patients undergoing endovas-cular therapy (EVT).PATIENTS AND METHODS: 219 patients who underwent EVT for the AIS were included in this retrospective design and cross-sectional study. The primary endpoint of the study was accepted as all-cause death including in-hospital death, 1-year death, and 3-years death. RESULTS: A total of 57 patients died in the hospital. In-hospital mortality rate was higher in the high CONUT group [36 (49.3%), 10 (13.7%), 11 (15.1%), p<0.001]. A total of 78 patients died within one year, and 1-year mortality was higher in the high CONUT group [43 (58.9%), 21 (28.8), 14 (19.2), p<0.001]. At the end of the 3-year fol-low-up, 90 patients had died, and the 3-year mortality rate was significantly higher in groups with a high CONUT score than in those with a low CONUT score (p<0.001).CONCLUSIONS: A higher CONUT score, cal-culated easily by simple scoring with parame-ters studied from peripheral blood before the EVT procedure, is an independent predictor of in-hospital, 1-year, and 3-years all-cause mor-tality.