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Öğe Effect of chemotherapeutic agents on distraction osteogenesis - An experimental investigation in rabbits(Springer-Verlag, 2001) Subasi, M; Kapukaya, A; Kesemenli, C; Balci, TA; Buyukbayram, H; Ozates, MLimb-salvage operations such as vascularised or non-vascularised osseous grafts and allograft and callus distraction methods have replaced amputations because of the increase in the life expectancy of patients with malignant tumours. In this study we aimed to evaluate the effects of chemotherapeutic agents on distraction osteogenesis. For this purpose, 23 rabbits randomly divided into two groups were included in the study. The experimental group and the control group consisted of 12 rabbits and I I rabbits, respectively. The experimental group were administered chemotherapeutic agents with the protocol identified in the osteogenic sarcoma regimen. All the subjects were corticotomised in the metaphyseal-diaphyseal region, and both groups underwent distraction with a circular ring fixator. X-ray films, bone scintigraphy and histopathological examination were pet-formed three times during the study. No difference between the two groups was observed in radiological, scintigraphical and histopathological studies carried out before the distraction period and following the end of the distraction period. In this study, it was shown that the use of antineoplastic drugs has no significant negative effect on distraction osteogenesis applied for reconstruction in rabbits. We think that it can be an alternative treatment method in humans as well.Öğe Lumbar epidural brucellar abscess causing nerve root compression(Stockton Press, 1999) Ozates, M; Özkan, Ü; Bükte, Y; Ceviz, A; Sari, I; Simsek, MObjectives: To evaluate the usefulness of MR sequences for the differential diagnosis of spinal brucellar abscesses which mimic lumbar disc herniation. Methods: We analyzed six patients with brucellar abscesses. who had symptoms mimicking lumbar disc herniation. The study group consisted of three women. and three men who were 15 - 67 (mean = 37) years old. Patients were imaged in the axial and sagittal planes with a I.0-T MR scanner using a spine coil. Results: The level of abscesses were accurate in 100% (six of six)of patients with MR imaging. MRI examinations revealed an extradural soft tissue mass which were iso- to hypointense compared to spinal cord on T1WI and hyperintense on T2-weighted images. By contrast study, diffuse homogeneous or slightly heterogeneous enhancements were seen. Conclusion: Lumbar extradural brucellar abscess can have lumbar disc disease symptoms. MRI may non-invasively and rapidly reveal the presence of spinal abscess and degree of extension to the spinal canal. Extradural brucellar abscess should be included in the differential diagnosis of radicular symptoms caused by disc herniation.Öğe Normal configuration of the anterior commissure of the glottis on magnetic resonance imaging(Springer Verlag, 2000) Cüreoglu, S; Osma, Ü; Ozates, MThe purpose of this study was to evaluate the normal width of the anterior commissure of the glottis by measuring its dimensions in patients who had no laryngeal disease on magnetic resonance imaging (MRI), but had unrelated cervical pathology. In all, 27 patients were studied. Axial images through the arytenoid commissure at the level of the vocalis muscle and/or vocal process of the arytenoid cartilage were magnified on MRI. The anteroposterior width of the anterior commissure was measured by using an electronic ruler having 1-mm marks. The average width of the anterior commissure was 1.59 +/- 0.6 mm, varying from a minimum width of 1 mm to a maximum width of 3 mm. The width was less than or equal to 2 mm in 25 patients (92.5%). Our results showed that all of the patients studied had measurable mucosal thicknesses at the level of anterior commissure greater than or equal to 1.0 mm.Öğe A pericardial hydatid cyst extending to the left lobe of the liver: the diagnostic value of MRI(Springer-Verlag, 2000) Ozates, M; Sari, I[Abstract Not Available]