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    Analysis of Ovarian Pathology in Children: Ten-years Experience
    (2023) Arslan, Serkan; Basuguy, Erol; Aydoğdu, Bahattin; Otcu, Serap Mutlu Özçelik; Salık, Fikret; Okur, Mehmet Hanifi
    Objective: In this study, we aimed to analyze whether laparoscopy is a feasible and safe surgical option for ovarian pathologies in children. Method: Our study included 43 patients who were followed up and treated for ovarian pathology in our clinic between January 1, 2012, and January 1, 2022. The clinical information and data for the patients were reviewed retrospectively. The patients were divided into 2 groups: Laparoscopy and the laparotomy group. Demographic data of the patients, complaints at presentation, localization of the mass, laboratory hormone levels and surgical findings, histopathological diagnoses, treatment methods, and treatment results were evaluated. Results: In the study, 43 female patients with a mean age of 9.6 years (1 month-15 years) were evaluated. It was the most common on the right side (58%). The most common symptom was abdominal pain (70%). Thirteen (30%) patients had acute abdomen findings. For surgical intervention, laparoscopy was performed in 22 (51%) patients and laparotomy was performed in 19 (44%) patients. Unilateral oophorectomy or salpingo-oophorectomy was performed in 28 (65%) of the patients as surgical treatment. Twenty-three (53%) of the ovarian pathologies were neoplastic, and 20 (47%) patients were non-neoplastic. Pathological diagnoses of ovarian pathologies 19 (44%) patients had ovarian torsion and 14 (33%) patients had teratoma. The operation time was shorter in the laparoscopy group (p<0.05). Tumor size was smaller in the laparoscopy group and larger in the conventional laparotomy surgery group (p<0.05). There was no significant difference between the laparoscopy group and the laparotomy surgery group in terms of age, tumor size, malignancy status, the presence of neoplastic mass, laterality, and tumor markers (p>0.05). While 42 of 43 patients survived, one patient with immature teratoma died from tumor-associated metastasis. Conclusion: Although the majority of ovarian pathologies are benign, since malignant masses may occur, surgery should be performed as early as possible. In lesions that are thought to be benign, ovarian- sparing surgery should be performed as much as possible. Laparoscopy is a feasible and safe surgical option for ovarian pathologies even, in malignant patients.
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    Öğe
    SPERM PARAMETERS' PREDICTIVE VALUE IN INTRAUTERINE INSEMINATION SUCCESS: A SINGLE-CENTER EXPERIENCE
    (Bilal GÜMÜŞ, 2023) Afşin, Muhamet; Nursal, Ayşe Feyda; Otcu, Serap Mutlu Özçelik; Yavuz, Dilek; Ege, Serhat
    Although intrauterine insemination is a widely used assisted reproductive technique there is no consensus on sperm parameters that affect the probability of pregnancy. Therefore, the purpose of this study was to determine whether semen parameters affect intrauterine insemination success. A total of 403 couples (345 negative pregnancies, and 58 positive pregnancy) that underwent 549 intrauterine insemination treatment cycles for heterogenous indications were included in the study. Clomiphen citrate, letrazole and/or gonadotropins were used for ovarian stimulation in women in this study. The spermiogram tests of the spouse of receiving IUI tretment were examined. Clinical pregnancy occurred in 58 of 549 intrauterine insemination (10.56%). Unexplained infertility, polycystic ovary syndrome, and cervical-tubal factors were higher in positive pregnancy group compared to negative pregnancy group while male factor was more prevalant in negative pregnancy group comparison to positive pregnancy group (p=0.03). There was no statistical difference between women with positive and negative pregnancy in terms of age (? 35 and > 35), body mass index, infertility type, infertility time, endometrial thickness on HCG day, stimulation protocol, cycle numbers, number of insemination, estradiol, prolactin, LH, FSH, and TSH levels (p>0.05). The sperm characteristics in males [ejaculate volum, sperm concentration, total sperm count, motility, immotility, and total progressive motile sperm count] did not significantly differed between positive and negative pregnancy groups (p>0.05). Briefly, the present study found that the conception probability of intrauterine insemination did not correlate with the spermiogram parameters.