Yazar "Olmez G." seçeneğine göre listele
Listeleniyor 1 - 5 / 5
Sayfa Başına Sonuç
Sıralama seçenekleri
Öğe Clinical investigation: thyroid function test abnormalities in cardiac arrest associated with acute coronary syndrome.(2005) Iltumur K.; Olmez G.; Ariturk Z.; Taskesen T.; Toprak N.INTRODUCTION: It is known that thyroid homeostasis is altered during the acute phase of cardiac arrest. However, it is not clear under what conditions, how and for how long these alterations occur. In the present study we examined thyroid function tests (TFTs) in the acute phase of cardiac arrest caused by acute coronary syndrome (ACS) and at the end of the first 2 months after the event. METHOD: Fifty patients with cardiac arrest induced by ACS and 31 patients with acute myocardial infarction (AMI) who did not require cardioversion or cardiopulmonary resuscitation were enrolled in the study, as were 40 healthy volunteers. The patients were divided into three groups based on duration of cardiac arrest (<5 min, 5-10 min and >10 min). Blood samples were collected for thyroid-stimulating hormone (TSH), tri-iodothyronine (T3), free T3, thyroxine (T4), free T4, troponin-I and creatine kinase-MB measurements. The blood samples for TFTs were taken at 72 hours and at 2 months after the acute event in the cardiac arrest and AMI groups, but only once in the control group. RESULTS: The T3 and free T3 levels at 72 hours in the cardiac arrest group were significantly lower than in both the AMI and control groups (P < 0.0001). On the other hand, there were no significant differences between T4, free T4 and TSH levels between the three groups (P > 0.05). At the 2-month evaluation, a dramatic improvement was observed in T3 and free T3 levels in the cardiac arrest group (P < 0.0001). In those patients whose cardiac arrest duration was in excess of 10 min, levels of T3, free T3, T4 and TSH were significantly lower than those in patients whose cardiac arrest duration was under 5 min (P < 0.001, P < 0.001, P < 0.005 and P < 0.05, respectively). CONCLUSION: TFTs are significantly altered in cardiac arrest induced by ACS. Changes in TFTs are even more pronounced in patients with longer periods of resuscitation. The changes in the surviving patients were characterized by euthyroid sick syndrome, and this improved by 2 months in those patients who did not progress into a vegetative state.Öğe Comparison of continious epidural infusion and patient-controlled epidural analgesia in labour(1999) Turhanoglu S.; Ozyilmaz M.A.; Olmez G.; Tok D.; Bayhan N.This study was performed with 42 pregnant women, planned to have vaginal delivery. The patients were allocated randomly to one of the two groups. After inserting epidural catheter, 0.5 % bupivacaine 4 ml and fentanly 2 ml were diluted to 15 ml with 0.9 % saline and administered to all patients with the epidural catheter when VAS scores were greater than 4. Bupivacaine 0.125 % concentration prepared with 0.9 % saline for PCA pump and 30 min after the first close, PCA pump was activated. To group I (n=21), 12 ml/h-1 bupivacaine was administered as continuous epidural infusion (CEI) and the patients in group II (n=21) were allowed to self-administer 3 ml of bupivacaine with a lockout interval of 10 min. VAS scores in group II were significantly lower then group I (p<0.05) and total bupivacaine consumption was also higher in group I (p<0.05). We concluded that PCEA could be used in labour analgesia as an alternative method.Öğe Comparison of general and spinal anaesthesia in pregnant women with pregnancy induced hypertension(1999) Turhanoglu S.; Tok D.; Ozyilmaz M.A.; Bayhan N.; Olmez G.; Kaya S.; Yayla M.The technique of anaesthesia may become important when caeseraen section will be necessary instead of vaginal delivery in pregnant women with pregnancy induced hypertension. In our study, we compared general versus spinal anaesthesia in hypertensive pregnant women who had the same clinical conditions. Sixty pregnant women had taken to the study and allocated randomly into two groups. In the first group (n=30) general anaesthesia, and in second group (n=30) spinal anaesthesia were administered to the patients. Heart rate (HR), systolic arterial pressure (SAP) and diastolic arterial pressure (DAP) in the periods of pre, per (1., 3., 5. minutes and every 5 minute for thirty minutes) and postoperative (1., 30. and 60. minutes), APGAR scores at 1. and 5. minutes, uterine incision-cordon clamping time (Ui-Cc) and the time of first analgesic requirement in the postoperative period were recorded. The values of HR, SAP and DAP were significantly lower in the group of spinal anaesthesia (p<0.05). APGAR scores at the first minute were found significantly better in the group of spinal anaesthesia than the group of general anaesthesia (p<0.05). The times of first analgesic requirements were significantly shorter in the group of general anaesthesia (p<0.05). We concluded that spinal anaesthesia may be performed in preeclamptic women undergoing caeserean section with safe if the anaesthesiologist takes the necessary measures.Öğe The effects of magnesium sulphate and alfentanil combination on haemodynamic control in general anaesthesia(1999) Turhanoglu S.; Ozyilmaz M.A.; Cinar F.S.; Tok D.; Olmez G.; Bayhan N.Sixty ASA class I or II patients were included to the study in which the effects of magnesium sulphate and alfentanil combination on the haemodynamic response to tracheal intubation and intraoperative haemodynamic control had been investigated. The patients were randomly allocated into three groups. At the induction of anaesthesia, the patients of group I (n=20) were received isotonic sodium chloride IV bolus and infusion, and 10 ?g/kg alfentanil, group II (n=20) were received IV magnesium sulphate 20 mg/kg bolus and 10 mg/kg/h infusion, and group III (n=20) were received IV magnesium sulphate 20 mg/kg bolus with 10 mg/kg/h infusion and 10 ?g/kg alfentanil. Anaesthesia induction and maintenance were performed respectively with thiopentone 5 mg/kg, isoflurane (% 1-1,5) in 50 % nitrous oxide and 50 % oxygen in all groups. Magnesium and alfentanil combination produced better control of arterial pressure and heart rate than magnesium and alfentanil alone (p<0.05). Furthermore, the consumption of alfentanil during the surgery were found significantly higher in group I than groups II and III (p<0.05). In conclusion we considered that the doses of magnesium sulphate and alfentanil combination in this study were adequate to attenuate the haemodynamic response to tracheal intubation and produce better control of arterial pressure and heart rate.Öğe The effects of prophylactic ondansetron administration time on postoperative nausea and vomiting at laparoscopic gynecologic procedures(1999) Turhanoglu S.; Ozyilmaz M.A.; Tok D.; Olmez G.; Bayhan N.The effects of ondansetron on postoperative nausea and vomiting (PONV) were investigated in laparoscopic gynecologic procedures and 120 patients were included to the study. Ondansetron 4 mg was administered via intravenous route to group I (n=30) immediately before induction, to group II (n=30) fifteen minutes before ending of surgery and also to group III (n=30) one hour before anaesthesia induction via oral route. Any drugs weren't given for preventing PONV to group IV (n=30) and was accepted as a control group. The patients were followed postoperatively in three periods as 0-2, 2-6 and 6-24 hours to assess PONV. Metoclopramide 10 mg was administered IV to the patients if necessary. Incidence of nausea were significantly lower in the patients of group I at the second and third periods (p<0.05). The incidence of vomiting were seen significantly low in the patients of groups I and II during the first period and vomiting were not present in the first group during the second and third periods (p<0.05). We concluded that the incidence of PONV could be decreased by using IV ondansetron 4 mg immediately before anesthesia induction or at the end of surgery in laparoscopic gynecologic procedures.
